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公开(公告)号：US20230340155A1
公开(公告)日：2023-10-26
申请号：US18331280
申请日：2023-06-08
Applicant: Janssen Biotech, Inc.
Inventor： Qiang Chen , Suzanne Cole , Karen Duffy , Yanxia Guo , Debra Gardner , Damon Hamel , Shannon Hitchcock , Ann Lacombe , Jinquan Luo , Ravi Malaviya , Yevgeniya Orlovsky , Pejman Soroosh , Melissa Swiecki , Deepti Wilkinson
CPC classification number: C07K16/40 , A61K39/3955 , A61P37/06 , C07K16/065 , C07K16/18 , C07K16/2818 , C12N15/00 , A61K2039/57
Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
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2.发明申请公开(公告)号：US20210040210A1
公开(公告)日：2021-02-11
申请号：US16937285
申请日：2020-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , John Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Degang Song , Raymond Brittingham , Sathyadevi Venkataramani , Sanjaya Singh , Yonghong Zhao , Fang Yi , Sherry Lynn La Porte
Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
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公开(公告)号：US10155809B2
公开(公告)日：2018-12-18
申请号：US15707317
申请日：2017-09-18
Applicant: Janssen Biotech, Inc.
Inventor： Ellen Chi , Judith Connor , Chichi Huang , Jarrat Jordan , Xiefan Lin-Schmidt , Jinquan Luo , Lu Lu , Christian Martinez , Galina Obmolova , Ronald Swanson
Abstract: Broadly neutralizing interferon-α and interferon-ω antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFNα and IFNω.
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公开(公告)号：US09932404B2
公开(公告)日：2018-04-03
申请号：US15345860
申请日：2016-11-08
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: A61K39/395 , C07K16/28 , C07H21/04 , C12N15/117 , C07K14/705 , C12N5/10 , C12N5/12 , C12N15/63 , A61K39/00
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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公开(公告)号：US20180079809A1
公开(公告)日：2018-03-22
申请号：US15830586
申请日：2017-12-04
Applicant: Janssen Biotech, Inc.
Inventor： Jill Giles-Komar , George Heavner , David Knight , Jinquan Luo , David Peritt , Bernard Scallon , David Shealy
IPC: C07K16/24 , C12Q1/68 , C07K14/54 , A61K31/56 , A61K38/27 , A61K39/395 , A61K45/06 , A61K51/00 , A61K31/137 , A61K39/00
CPC classification number: C07K16/244 , A61K31/137 , A61K31/56 , A61K38/27 , A61K39/3955 , A61K45/06 , A61K51/00 , A61K2039/505 , C07K14/54 , C07K14/5434 , C07K2317/14 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C12Q1/6876
Abstract: An anti-IL-12 antibody or fragment thereof that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody or fragment thereof, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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Patent Agency Ranking
公开(公告)号：US09714287B2
公开(公告)日：2017-07-25
申请号：US15337512
申请日：2016-10-28
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , C07K16/24 , A61K45/06 , A61K39/00
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：US20170066831A1
公开(公告)日：2017-03-09
申请号：US14939624
申请日：2015-11-12
Applicant: Janssen Biotech, Inc.
Inventor： Karen Duffy , Natalie Fursov , LeRoy Hall , Catherine Healy , Roberta Lamb , Jinquan Luo , Ravi Malaviya , Michael Naso , Michael Pratta , Mark Tornetta , John Wheeler , Sheng-Jiun Wu
IPC: C07K16/28
CPC classification number: C07K16/2866 , A61K38/012 , A61K39/3955 , A61K2039/505 , C07K16/44 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
Abstract translation: 本发明涉及ST2L拮抗剂，编码拮抗剂或其片段的多核苷酸，以及制备和使用上述物质的方法。
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公开(公告)号：US20160319014A1
公开(公告)日：2016-11-03
申请号：US15217099
申请日：2016-07-22
Applicant: Janssen Biotech, Inc.
Inventor： Jill Giles-Komar , George Heavner , David Knight , Jinquan Luo , David Peritt , Bernard Scallon , David Shealy
CPC classification number: C07K16/244 , A61K31/137 , A61K31/56 , A61K38/27 , A61K39/3955 , A61K45/06 , A61K51/00 , A61K2039/505 , C07K14/54 , C07K14/5434 , C07K2317/14 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C12Q1/6876
Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 结合IL-12蛋白的一部分对应于至少一个氨基酸残基的抗IL-12抗体，其选自残基15,17-21,23,40-43,45-47,54 -56和58-62的IL-12的p40亚基的氨基酸序列，包括编码至少一种抗IL-12抗体，载体，宿主细胞，转基因动物或植物的分离的核酸，以及制备方法 并且其使用在诊断和/或治疗组合物，方法和装置中具有应用。
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9.发明授权公开(公告)号：US09428579B2
公开(公告)日：2016-08-30
申请号：US14512757
申请日：2014-10-13
Applicant: Janssen Biotech, Inc.
Inventor： Jill Giles-Komar , George Heavner , David Knight , Jinquan Luo , David Peritt , Bernard Scallon , David Shealy
IPC: A61K39/395 , C07K16/24 , C07K14/54 , A61K31/137 , A61K31/56 , A61K38/27 , A61K45/06 , A61K51/00 , A61K39/00
CPC classification number: C07K16/244 , A61K31/137 , A61K31/56 , A61K38/27 , A61K39/3955 , A61K45/06 , A61K51/00 , A61K2039/505 , C07K14/54 , C07K14/5434 , C07K2317/14 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C12Q1/6876
Abstract: An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 结合IL-12蛋白的一部分对应于至少一个氨基酸残基的抗IL-12抗体，其选自残基15,17-21,23,40-43,45-47,54 -56和58-62的IL-12的p40亚基的氨基酸序列，包括编码至少一种抗IL-12抗体，载体，宿主细胞，转基因动物或植物的分离的核酸，以及制备方法 并且其使用在诊断和/或治疗组合物，方法和装置中具有应用。
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公开(公告)号：US09090694B2
公开(公告)日：2015-07-28
申请号：US13798204
申请日：2013-03-13
Applicant: Janssen Biotech, Inc.
Inventor： Karen Duffy , Natalie Fursov , LeRoy Hall , Catherine Healy , Roberta Lamb , Jinquan Luo , Ravi Malaviya , Michael Naso , Michael Pratta , Mark Tornetta , John Wheeler , Sheng-Jiun Wu
CPC classification number: C07K16/2866 , A61K38/012 , A61K39/3955 , A61K2039/505 , C07K16/44 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
Abstract translation: 本发明涉及ST2L拮抗剂，编码拮抗剂或其片段的多核苷酸，以及制备和使用上述物质的方法。
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