公开(公告)号：US20230144627A1

公开(公告)日：2023-05-11

申请号：US17967443

申请日：2022-10-17

Applicant: Janssen Biotech, Inc.

Inventor： Gilles Bignan ,  Peter Connolly ,  James Patrick Edwards ,  Stuart Emanuel ,  Sylvie Laquerre ,  Tianbao Lu ,  Mark Richter ,  Leonid Beigelman ,  Santhosh Kumar Thatikonda ,  Guangyi Wang ,  Minghong Zhong

IPC: C07H21/02 ,  A61K9/00 ,  A61P31/20 ,  A61P35/00 ,  A61K9/10 ,  A61P31/12 ,  A61K31/7076

CPC classification number: C07H21/02 ,  A61K9/0095 ,  A61P31/20 ,  A61P35/00 ,  A61K9/10 ,  A61P31/12 ,  A61K31/7076

Abstract: Disclosed are compounds, compositions and methods for treating viral infections, diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows:




wherein R1A, R1B, R1C, B1, R2A, and R2B are defined herein.

公开(公告)号：US11472830B2

公开(公告)日：2022-10-18

申请号：US15820592

申请日：2017-11-22

Applicant: Janssen Biotech, Inc.

Inventor： Gilles Bignan ,  Peter Connolly ,  James Patrick Edwards ,  Stuart Emanuel ,  Sylvie Laquerre ,  Tianbao Lu ,  Mark Richter ,  Leonid Beigelman ,  Santhosh Kumar Thatikonda ,  Guangyi Wang ,  Minghong Zhong

IPC: C07H21/02 ,  A61P31/12 ,  A61K31/7084 ,  A61K9/00 ,  A61P31/20 ,  A61P35/00 ,  A61K9/10 ,  A61K31/7076

Abstract: Disclosed are compounds, compositions and methods for treating viral infections, diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R1A, R1B, R1c, B1, R2A, and R2B are defined herein.

公开(公告)号：US20180162899A1

公开(公告)日：2018-06-14

申请号：US15820592

申请日：2017-11-22

Applicant: Janssen Biotech, Inc.

Inventor： Gilles Bignan ,  Peter Connolly ,  James Patrick Edwards ,  Stuart Emanuel ,  Sylvie Laquerre ,  Tianbao Lu ,  Mark Richter ,  Leonid Beigelman ,  Santhosh Kumar Thatikonda ,  Guangyi Wang ,  Minghong Zhong

IPC: C07H21/02 ,  A61K9/00 ,  A61K9/10 ,  A61P35/00 ,  A61P31/20

Abstract: Disclosed are compounds, compositions and methods for treating viral infections, diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R1A, R1B, R1c, B1, R2A, and R2B are defined herein.