公开(公告)号：US20230146410A1

公开(公告)日：2023-05-11

申请号：US17982218

申请日：2022-11-07

Applicant: Janssen Biotech, Inc.

Inventor： Stuart Emanuel ,  Mark Richter ,  Peter J. Connolly ,  James Patrick Edwards ,  Guangyi Wang ,  Santhosh Kumar Thatikonda ,  Leonid Beigelman ,  Minghong Zhong ,  Gilles Bignan ,  Wim Schepens ,  Marcel Viellevoye ,  Johannes Wilhelmus John Fitzgerald Thuring

IPC: C07H21/00 ,  A61P31/12 ,  A61P35/00

CPC classification number: C07H21/00 ,  A61P31/12 ,  A61P35/00

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows:




wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.

公开(公告)号：US11492367B2

公开(公告)日：2022-11-08

申请号：US16478866

申请日：2018-01-26

Applicant: Janssen Biotech, Inc.

Inventor： Stuart Emanuel ,  Mark Richter ,  Peter J. Connolly ,  James Patrick Edwards ,  Guangyi Wang ,  Santhosh Kumar Thatikonda ,  Leonid Beigelman ,  Minghong Zhong ,  Gilles Bignan ,  Wim Schepens ,  Marcel Viellevoye ,  Johannes Wilhelmus John Fitzgerald Thuring

IPC: C07H21/02 ,  A61K48/00 ,  C07H21/00 ,  A61P31/12 ,  A61P35/00

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.