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公开(公告)号：US11492367B2
公开(公告)日：2022-11-08
申请号：US16478866
申请日：2018-01-26
Applicant: Janssen Biotech, Inc.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James Patrick Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Minghong Zhong , Gilles Bignan , Wim Schepens , Marcel Viellevoye , Johannes Wilhelmus John Fitzgerald Thuring
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.
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公开(公告)号：US11597746B2
公开(公告)日：2023-03-07
申请号：US17260886
申请日：2019-07-16
Applicant: JANSSEN BIOTECH, INC.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James P. Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Gilles Bignan , Wim Bert Griet Schepens , Marcel Viellevoye , Johannes Wilhelmus J. F. Thuring
IPC: C07H19/207 , C07H19/23 , A61P35/00
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.
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Patent Agency Ranking
公开(公告)号：US20180170909A1
公开(公告)日：2018-06-21
申请号：US15847999
申请日：2017-12-20
Applicant: Janssen Biotech, Inc.
Inventor： Tianbao Lu , Brett Douglas Allison , Joseph Kent Barbay , Peter J. Connolly , Maxwell David Cummings , Gaston Diels , James Patrick Edwards , Kevin D. Kreutter , Ulrike Philippar , Fang Shen , Johannes Wilhelmus John Fitzgerald Thuring , Tongfei Wu
IPC: C07D401/14 , C07D401/12 , A61P35/00 , A61P19/02 , A61P1/00 , A61P11/06 , A61P37/00
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.
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公开(公告)号：US20230287034A1
公开(公告)日：2023-09-14
申请号：US18177864
申请日：2023-03-03
Applicant: JANSSEN BIOTECH, INC.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James P. Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Gilles Bignan , Wim Bert Griet Schepens , Marcel Viellevoye , Johannes Wilhelmus J.F. Thuring
IPC: C07H19/207 , A61P35/00 , C07H19/23
CPC classification number: C07H19/207 , A61P35/00 , C07H19/23
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows:
wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.-
公开(公告)号：US20230146410A1
公开(公告)日：2023-05-11
申请号：US17982218
申请日：2022-11-07
Applicant: Janssen Biotech, Inc.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James Patrick Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Minghong Zhong , Gilles Bignan , Wim Schepens , Marcel Viellevoye , Johannes Wilhelmus John Fitzgerald Thuring
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows:
wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.-
公开(公告)号：US11021511B2
公开(公告)日：2021-06-01
申请号：US16478864
申请日：2018-01-26
Applicant: Janssen Biotech, Inc.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James Patrick Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Minghong Zhong , Gilles Bignan
IPC: A61K31/70 , A01N43/04 , C07H21/00 , A61P31/12 , A61P35/00 , A61K31/708 , A61K31/7084 , A61K31/7076
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R1A, R1B, R1C, R1D, B1, R2A, R2B, R2C, R2D, and R2E are defined herein and Formula (II) wherein R1H, R1K, R1J, and R2L are defined herein.
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公开(公告)号：US20210277046A1
公开(公告)日：2021-09-09
申请号：US17260886
申请日：2019-07-16
Applicant: JANSSEN BIOTECH, INC.
Inventor： Stuart Emanuel , Mark Richter , Peter J. Connolly , James P. Edwards , Guangyi Wang , Santhosh Kumar Thatikonda , Leonid Beigelman , Gilles Bignan , Wim Bert Griet Schepens , Marcel Viellevoye , Johannes Wilhelmus J.F. Thuring
IPC: C07H19/207 , A61P35/00 , C07H19/23
Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1′, X1, B1, R2, R2′, B2, X2, R3, Z-M-Y, and Y1-M1-Z1 are as defined herein.
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