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公开(公告)号：US20240279281A1
公开(公告)日：2024-08-22
申请号：US18412678
申请日：2024-01-15
发明人： Stephanie A. BARROS , Santhosh Francis Neelamkavil , Chengzao SUN , Boying Guo , Charles Hendrick , David Marcoux , Sandeep Somani , Tho Thieu , Jing Zhang , Danila Branca , Roberto Costante , Ashok Bhandari , Gregory Thomas Bourne , Brian Troy Frederick
摘要： The present disclosure relates to peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.
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公开(公告)号：US20240173309A1
公开(公告)日：2024-05-30
申请号：US18495457
申请日：2023-10-26
发明人： Santhosh NEELAMKAVIL , Chengzao SUN , Sandeep SOMANI , Stephanie A. BARROS , Raymond J. PATCH , Jing ZHANG , Douglas RIEXINGER , Charles HENDRICK , Elisabetta BIANCHI , Roberto COSTANTE , Federica ROSOLIA , Martina LOLLOBRIGIDA , Sonia DEL RIZZO , Danila BRANCA , Ashok BHANDARI , James DANIEL , Tran Trung TRAN , Brian FREDERICK
IPC分类号： A61K31/4439 , A61P37/02
CPC分类号： A61K31/4439 , A61P37/02
摘要： The present invention relates to novel lipidated peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof, corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders.
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3.发明公开公开(公告)号：US20240150405A1
公开(公告)日：2024-05-09
申请号：US18492612
申请日：2023-10-23
发明人： Chengzao SUN , Brian Troy FREDERICK , Sandeep SOMANI , Gregory Thomas BOURNE , Raymond PATCH , Ashok BHANDARI , Raffaele INGENITO , Roberto COSTANTE , Danila BRANCA , Elisabetta BIANCHI
IPC分类号： C07K7/64
摘要： The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases.
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