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公开(公告)号：US20210023082A1
公开(公告)日：2021-01-28
申请号：US17012286
申请日：2020-09-04
发明人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Werner Embrachts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jeromir Vlach
IPC分类号： A61K31/505 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , A61P31/12 , A61K31/513 , C07D401/10 , C07D403/10 , C07D239/48 , C07D487/04 , C07D495/04 , A61K31/506 , A61K31/5377
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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公开(公告)号：US20200061059A1
公开(公告)日：2020-02-27
申请号：US16530385
申请日：2019-08-02
发明人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Werner Embrechts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jaromir Vlach
IPC分类号： A61K31/513 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , C07D239/48 , C07D487/04 , C07D495/04 , A61K31/506 , A61K31/5377 , A61P31/12
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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公开(公告)号：US10420767B2
公开(公告)日：2019-09-24
申请号：US15867041
申请日：2018-01-10
发明人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Werner Embrechts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jaromir Vlach
IPC分类号： A61K31/505 , A61K31/5377 , A61K31/506 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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公开(公告)号：US10272085B2
公开(公告)日：2019-04-30
申请号：US15209637
申请日：2016-07-13
发明人： David McGowan , Pierre Jean-Marie Bernard Raboisson , Werner Embrechts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jaromir Vlach
IPC分类号： A61K31/505 , A61K31/5377 , A61K31/506 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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![Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases](/abs-image/US/2019/04/16/US10259814B2/abs.jpg.150x150.jpg)
5.发明授权公开(公告)号：US10259814B2
公开(公告)日：2019-04-16
申请号：US15333947
申请日：2016-10-25
发明人： David Craig McGowan , Stefaan Julien Last , Serge Maria Aloysius Pieters , Werner Embrechts , Tim Hugo Maria Jonckers , Pierre Jean-Marie Bernard Raboisson
IPC分类号： C07D487/04 , A61K31/519 , A61K31/407 , A61P31/12 , C07D519/00
摘要： This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
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6.发明授权公开(公告)号：US09663474B2
公开(公告)日：2017-05-30
申请号：US14443305
申请日：2013-11-15
发明人： Stefaan Julien Last , David Craig McGowan , Werner Embrechts , Serge Maria Aloysius Pieters , Tim Hugo Maria Jonckers , Pierre Jean-Marie Bernard Raboisson
IPC分类号： C07D239/84 , C07D239/95 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
CPC分类号： C07D239/84 , C07D239/95 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
摘要： This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
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公开(公告)号：US20170239245A1
公开(公告)日：2017-08-24
申请号：US15209637
申请日：2016-07-13
发明人： David Mc GOWAN , Pierre Jean-Marie Bernard Raboisson , Werner Embrechts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jaromir Vlach
IPC分类号： A61K31/505 , A61K31/5377 , A61K31/506
CPC分类号： A61K31/505 , A61K31/506 , A61K31/5377 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D495/04
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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![Pyrrolo[3,2-]pyrimidine derivatives for the treatment of viral infections and other diseases](/abs-image/US/2016/11/22/US09499549B2/abs.jpg.150x150.jpg)
8.发明授权公开(公告)号：US09499549B2
公开(公告)日：2016-11-22
申请号：US14434021
申请日：2013-10-09
发明人： David Craig McGowan , Stefaan Julien Last , Serge Maria Aloysius Pieters , Werner Embrechts , Tim Hugo Maria Jonckers , Pierre Jean-Marie Bernard Raboisson
IPC分类号： C07D487/04 , A61K31/519 , C07D519/00
CPC分类号： C07D487/04 , A61K31/407 , A61K31/519 , C07D519/00
摘要： This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
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9.发明申请HETEROCYCLIC SUBSTITUTED 2-AMINO QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS 有权用于治疗病毒感染的杂环取代的2-氨基喹唑啉衍生物公开(公告)号：US20150284339A1
公开(公告)日：2015-10-08
申请号：US14443305
申请日：2013-11-15
发明人： Stefaan Julien Last , David Craig Mc Gowan , Werner Embrechts , Serge Maria Aloysius Pieters , Tim Hugo Maria Jonckers , Pierre Jean-Marie Bernard Raboisson
IPC分类号： C07D239/84 , C07D403/12 , C07D413/12 , C07D401/12 , C07D417/12
CPC分类号： C07D239/84 , C07D239/95 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
摘要： This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
摘要翻译： 本发明涉及杂环取代的2-氨基 - 喹唑啉衍生物，其制备方法，药物组合物及其在治疗病毒感染中的用途。
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公开(公告)号：US11541050B2
公开(公告)日：2023-01-03
申请号：US17012286
申请日：2020-09-04
发明人： David Mc Gowan , Pierre Jean-Marie Bernard Raboisson , Werner Embrechts , Tim Hugo Maria Jonckers , Stefaan Julien Last , Serge Maria Aloysius Pieters , Jaromir Vlach
IPC分类号： A61K31/505 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D471/04 , A61P31/12 , A61K31/513 , C07D401/10 , C07D403/10 , C07D239/48 , C07D487/04 , C07D495/04 , A61K31/506 , A61K31/5377
摘要： This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
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