公开(公告)号：US20070203556A1

公开(公告)日：2007-08-30

申请号：US11364240

申请日：2006-02-28

申请人： Jean Rutten ,  Leonardus Kretzers ,  Karel Smits

发明人： Jean Rutten ,  Leonardus Kretzers ,  Karel Smits

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  A61N1/0504 ,  A61N1/057 ,  A61N1/3968

摘要： A medical device that includes a lead having a lead body extending from a proximal end to a distal end, and a housing having a connector block for receiving the proximal end of the lead body. A fixation mechanism is positioned proximal to an electrode coil located at the distal end of the lead body, and a fixation member or a plurality of fixation members extend from the fixation mechanism from a fixation member proximal end to a fixation member distal end. The fixation members are advanceable from a first position corresponding to the fixation member distal end being positioned along the lead during subcutaneous placement of the lead, to a second position corresponding to the fixation member distal end being positioned away from the lead to fixedly engage the lead at a target site.

摘要翻译： 一种医疗装置，其包括具有从近端延伸到远端的引线主体的引线，以及具有用于接收引线主体的近端的连接器块的壳体。 定位机构位于位于引线主体的远端的电极线圈的近侧，并且固定构件或多个固定构件从固定构件从固定构件近端延伸到固定构件远端。 所述固定构件可从对应于所述固定构件远端的第一位置推进，所述第一位置在所述引线的皮下放置期间沿着所述引线定位到与固定构件远端相对应的第二位置，所述第二位置远离所述引线定位，以固定地接合所述引线 在目标网站。

公开(公告)号：US20070250123A1

公开(公告)日：2007-10-25

申请号：US11379287

申请日：2006-04-19

申请人： Jean Rutten ,  Karel Smits

发明人： Jean Rutten ,  Karel Smits

IPC分类号： A61N1/00

CPC分类号： A61N1/375 ,  A61N1/3752

摘要： An implantable medical device is provided for sensing cardiac activity within a patient's body. The device comprises a canister, control circuitry disposed within the canister, and a lead assembly extending from the canister. At least one sense electrode is coupled to the circuitry and disposed on the lead assembly for sensing cardiac activity. At least one spacer is coupled between the lead assembly and the canister for maintaining a minimum predetermined distance between the at least one sense electrode and the canister.

摘要翻译： 提供了一种用于感测患者体内的心脏活动的可植入医疗装置。 该装置包括罐，设置在罐内的控制电路以及从罐延伸的引导组件。 至少一个感测电极耦合到电路并且布置在引导组件上以感测心脏活动。 至少一个间隔件联接在引导组件和罐之间，用于保持至少一个感测电极和罐之间的最小预定距离。

公开(公告)号：US06278897B1

公开(公告)日：2001-08-21

申请号：US09204314

申请日：1998-12-03

申请人： Jean J. G. Rutten ,  Karel Smits ,  Nicolaas Lokhoff ,  Paulus Van Venrooij

发明人： Jean J. G. Rutten ,  Karel Smits ,  Nicolaas Lokhoff ,  Paulus Van Venrooij

IPC分类号： A61N105

CPC分类号： A61N1/056 ,  A61M25/0668

摘要： A medical electrical lead and introducer system. The lead is a single pass, dual chamber lead, which features in one embodiment an atrial tine. The introducer system is particularly designed for introduction of single pass, dual chamber lead which has an atrial tine. The introducer system facilitates the introduction of a such lead into a patient's heart while safeguarding the tine from damage due to kinking during lead positioning. The lead is a single pass lead which features an atrial tine while the introducer system is particularly designed for introduction of a such lead into a patient's heart so as to safeguard the tine from damage due to kinking during lead positioning. The lead is designed so as to electrically couple both the atrium and the ventricular chambers of the heart. The lead generally features several lengths each having differing stiffness as well as a pre-formed bend. The lead also features a atrial tine having an electrode at the tip. Due to the relatively fragile as well as difficult to maneuver lead, an introducer system is also disclosed. The introducer system is particularly designed to introduce such a lead. In use a removable tubing split element surrounds the atrial tine area of the lead while it is disposed through the introducer sheath, the split element both blocks the tine from lateral movement and fills up the space between the lead body and the introducer, thereby preventing blood leakage through the introducer. The element also has a longitudinal split for receiving the atrial tine while holding it against transverse movement when the lead is being repositioned. After optimal positioning of the lead, the tubing split element is withdrawn, and then the introducer is withdrawn. The tubing split element is a generally cylindrical piece of TEFLON, here called a tube split element, or just a “tube split”, is positioned around the lead body in the atrial tine area. The tube split element has a thickness which substantially fills the radial gap between the smaller diameter lead body and the introducer inner cylindrical wall, and has a longitudinal separation, or split, which accommodates the atrial tine, thereby permitting the tine to extend longitudinally but not transversely. The tubing split element is preferably mounted on the lead at the time of lead assembly. It has a length sufficient to extend proximally out of the introducer so that it can be withdrawn, and has a longitudinal tear line whereby the element can be separated and removed from the lead after final positioning of the lead.

公开(公告)号：US20070185502A1

公开(公告)日：2007-08-09

申请号：US11321390

申请日：2005-12-29

申请人： Karel Smits

发明人： Karel Smits

IPC分类号： A61B19/00

CPC分类号： A61N1/3622 ,  A61N1/3627 ,  A61N1/3682

摘要： A medical electrode delivery tool includes a distal portion coupled to an elongate shaft. The distal portion includes a generally ellipsoidal segment. The ellipsoidal segment includes a concave surface forming a cavity having an opening facing in a direction away from a longitudinal axis of the shaft and a convex surface overlying the concave surface and tapering to a distal end of the ellipsoidal segment.

摘要翻译： 医疗电极传送工具包括联接到细长轴的远端部分。 远侧部分包括大致椭圆形段。 所述椭圆形段包括凹形表面，所述凹形表面形成具有朝向远离所述轴的纵向轴线的方向的开口的腔体，以及覆盖所述凹形表面并且渐缩到所述椭圆形段的远端的凸形表面。

公开(公告)号：US20060030224A1

公开(公告)日：2006-02-09

申请号：US10914369

申请日：2004-08-09

申请人： Paul Degroot ,  Karel Smits

发明人： Paul Degroot ,  Karel Smits

IPC分类号： H01R4/48

CPC分类号： A61N1/3752 ,  A61N1/056 ,  A61N1/0587 ,  H01R4/36 ,  H01R2201/12

摘要： A medical electrical system includes a device including a connector port and an external electrically active surface and an auxiliary lead including a supplemental electrode and a connector end. The external electrically active surface of the device is adapted to receive the auxiliary lead connector end, thereby electrically coupling the supplemental electrode to the device via contact between the connector end and the external surface.

摘要翻译： 医疗电气系统包括包括连接器端口和外部电活动表面的设备以及包括补充电极和连接器端的辅助引线。 该装置的外部电活动表面适于接收辅助引线连接器端，从而通过连接器端和外表面之间的接触将辅助电极电耦合到装置。

公开(公告)号：US08532789B2

公开(公告)日：2013-09-10

申请号：US11364308

申请日：2006-02-28

申请人： Karel Smits

发明人： Karel Smits

IPC分类号： A61N1/00

CPC分类号： A61N1/3918 ,  A61N1/0504 ,  A61N1/0573 ,  A61N1/0587

摘要： A medical device that includes a lead having a lead body extending from a proximal end to a distal end, and a housing having a connector block for receiving the proximal end of the lead body. A fixation mechanism is positioned proximal to an electrode coil located at the distal end of the lead body, and includes a locking sleeve and a mating portion positioned along the lead body proximal to the electrode. The fixation mechanism is capable of being advance from a first state corresponding to a first inner diameter of the locking sleeve and a second state corresponding to a second inner diameter of the locking sleeve greater than the first inner diameter to fixed position the electrode at a target site.

摘要翻译： 一种医疗装置，其包括具有从近端延伸到远端的引线主体的引线，以及具有用于接收引线主体的近端的连接器块的壳体。 定位机构位于位于引线主体的远端的电极线圈的近侧，并且包括锁定套筒和配置部分，该配合部分沿导线体靠近电极定位。 固定机构能够从对应于锁定套筒的第一内径的第一状态和对应于大于第一内径的锁定套筒的第二内径的第二状态前进到将目标位置固定 现场。

公开(公告)号：US20070179539A1

公开(公告)日：2007-08-02

申请号：US11343346

申请日：2006-01-31

申请人： Paul Degroot ,  Karel Smits ,  William Flickinger

发明人： Paul Degroot ,  Karel Smits ,  William Flickinger

IPC分类号： A61N1/00

CPC分类号： A61N1/3962 ,  A61N1/3621 ,  A61N1/36535 ,  A61N1/36542

摘要： An implantable medical device and method are provided for determining if a patient is in a substantially horizontal position and delaying a programmed cardioversion/defibrillation shock therapy in response to determining the patient is in a substantially horizontal position. In various embodiments, the shock therapy may be delayed by adjusting tachycardia detection criteria or scheduling the shock therapy after a maximum tachycardia episode duration.

摘要翻译： 提供了可植入医疗装置和方法，用于确定患者是否处于基本上水平的位置，并且响应于确定患者处于基本上水平的位置而延迟编程的心脏复律/除颤休克疗法。 在各种实施例中，通过调节心动过速检测标准或在最大心动过速发作持续时间之后安排休克疗法可以延迟休克疗法。

公开(公告)号：US20070100382A1

公开(公告)日：2007-05-03

申请号：US11263101

申请日：2005-10-31

申请人： Karel Smits

发明人： Karel Smits

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61B5/04011 ,  A61B5/04085 ,  A61B5/7257 ,  A61N1/08 ,  A61N1/3925

摘要： Methods of implanting at least one lead for a cardio defibrillator using body surface potential (BSP) electrodes are disclosed. The methods may include installing defibrillation electrodes in a patient, attaching at least three BSP electrodes to the patient's skin, creating a potential difference between the defibrillation electrodes, and measuring the resulting body surface potential at the three BSP electrodes. Once the resulting BSP is measured, the methods may include determining the amplitude of a resultant vector formed by the measured BSP potential differences. The location of a defibrillation electrode may then be manipulated to increase the amplitude of the resultant vector formed by the measured BSP potential differences.

摘要翻译： 公开了使用身体表面电位（BSP）电极植入用于心脏除颤器的至少一个引线的方法。 所述方法可以包括在患者体内安装除颤电极，将至少三个BSP电极连接到患者皮肤上，产生除颤电极之间的电位差，并测量三个BSP电极处的所得体表面电位。 一旦测得了所得到的BSP，方法可以包括确定由测量的BSP电位差形成的合成矢量的振幅。 然后可以操纵除颤电极的位置以增加由测量的BSP电位差形成的合成矢量的振幅。

公开(公告)号：US20070203553A1

公开(公告)日：2007-08-30

申请号：US11364308

申请日：2006-02-28

申请人： Karel Smits

发明人： Karel Smits

IPC分类号： A61N1/00

CPC分类号： A61N1/3918 ,  A61N1/0504 ,  A61N1/0573 ,  A61N1/0587

摘要： A medical device that includes a lead having a lead body extending from a proximal end to a distal end, and a housing having a connector block for receiving the proximal end of the lead body. A fixation mechanism is positioned proximal to an electrode coil located at the distal end of the lead body, and includes a locking sleeve and a mating portion positioned along the lead body proximal to the electrode. The fixation mechanism is capable of being advance from a first state corresponding to a first inner diameter of the locking sleeve and a second state corresponding to a second inner diameter of the locking sleeve greater than the first inner diameter to fixed position the electrode at a target site.

摘要翻译： 一种医疗装置，其包括具有从近端延伸到远端的引线主体的引线，以及具有用于接收引线主体的近端的连接器块的壳体。 定位机构位于位于引线主体的远端的电极线圈的近侧，并且包括锁定套筒和配置部分，该配合部分沿导线体靠近电极定位。 固定机构能够从对应于锁定套筒的第一内径的第一状态和对应于大于第一内径的锁定套筒的第二内径的第二状态前进到将目标位置固定 现场。

公开(公告)号：US20050131475A1

公开(公告)日：2005-06-16

申请号：US10985341

申请日：2004-11-09

申请人： Karel Smits

发明人： Karel Smits

IPC分类号： A61N1/39

CPC分类号： A61N1/3918

摘要： The present invention provides systems, methods, components and medical devices for defibrillating a volume of excitable myocardial tissue. In one aspect, the invention delivers therapy via a pair of electrodes spaced from myocardial tissue with a first electrode disposed in a precordial location and spaced from myocardial tissue and a second electrode disposed in a non-precordial location. Another form of the invention includes methods of delivering cardioversion, defibrillation and/or cardiac pacing therapy by sensing cardiac events with at least a pair of electrodes located in one of a submuscular and a subcutaneous position. In this form of the invention the pair of electrodes are spaced from excitable heart tissue of the subject and cardiac therapy pulses are delivered via at least a pair of electrodes at a sufficient energy level to capture at least one ventricular chamber of the subject.

摘要翻译： 本发明提供用于去纤颤一定体积的可激发心肌组织的系统，方法，部件和医疗装置。 一方面，本发明通过与心肌组织间隔开的一对电极递送治疗，其中第一电极设置在心前部位置并与心肌组织间隔开，第二电极设置在非心脏前置位置。 本发明的另一种形式包括通过用位于肌肉下和皮下位置之一中的至少一对电极来感测心脏事件来递送心脏复律，除颤和/或心脏起搏治疗的方法。 在本发明的这种形式中，一对电极与受试者的兴奋性心脏组织隔开，并且心脏治疗脉冲经由至少一对电极以足够的能量水平递送以捕获受试者的至少一个心室。