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    Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process
    5.
    发明授权
    Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process 有权
    葡萄糖和维生素F的衍生物，包含其的组合物，用途和制备方法

    公开(公告)号：US07977318B2

    公开(公告)日：2011-07-12

    申请号：US11393829

    申请日：2006-03-31

    申请人： Jean-François Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    发明人： Jean-François Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    IPC分类号： A61K31/7024

    CPC分类号： C07H13/06 ,  A61K8/34 ,  A61K8/602 ,  A61K8/731 ,  A61K31/133 ,  A61K31/192 ,  A61K31/4412 ,  A61K31/7024 ,  A61K31/717 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  C07H1/00 ,  C07H13/02 ,  Y10S514/88

    摘要： An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.

    摘要翻译： 衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物 ，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍 头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸 与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

    Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process
    7.
    发明授权
    Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process 有权
    葡萄糖和维生素F的衍生物，包含其的组合物，用途和制备方法

    公开(公告)号：US07795230B2

    公开(公告)日：2010-09-14

    申请号：US11657532

    申请日：2007-01-25

    申请人： Jean-François Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    发明人： Jean-François Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    IPC分类号： C07H13/06

    CPC分类号： C07H13/06 ,  A61K8/34 ,  A61K8/602 ,  A61K8/731 ,  A61K31/133 ,  A61K31/192 ,  A61K31/4412 ,  A61K31/7024 ,  A61K31/717 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  C07H1/00 ,  C07H13/02 ,  Y10S514/88

    摘要： An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.

    摘要翻译： 衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物 ，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍 头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸 与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss
    8.
    发明授权
    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss 有权
    施用吡啶二羧酸化合物用于刺激或诱导人角质纤维的生长和/或阻止其损失

    公开(公告)号：US07598278B2

    公开(公告)日：2009-10-06

    申请号：US10410402

    申请日：2003-04-10

    申请人： Mario Dalko ,  Geneviéve Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    发明人： Mario Dalko ,  Geneviéve Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC分类号： A61K31/44

    CPC分类号： A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    摘要翻译： 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和的直链或支链C 1 -C 18烷基或芳基 该烷基或芳基任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代，或者R'和R“一起代表杂环，该组合物旨在诱导和/或刺激人的生长 角质纤维，如头发和睫毛，和/或减慢其损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS
    9.
    发明申请
    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS 审中-公开
    吡啶二羧酸化合物的施用用于刺激或诱导人类激素纤维的生长和/或损害它们的损失

    公开(公告)号：US20100105741A1

    公开(公告)日：2010-04-29

    申请号：US12650777

    申请日：2009-12-31

    申请人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    发明人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC分类号： A61K31/44

    CPC分类号： A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    摘要翻译： 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和和直链或支链的C 1 -C 18烷基或芳基， 任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代的烷基或芳基，或R'和R“一起表示杂环，该组合物旨在诱导和/或刺激人角质纤维的生长， 如头发和睫毛，和/或减慢他们的损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。