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    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss
    1.
    发明授权
    Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss 有权
    施用吡啶二羧酸化合物用于刺激或诱导人角质纤维的生长和/或阻止其损失

    公开(公告)号：US07598278B2

    公开(公告)日：2009-10-06

    申请号：US10410402

    申请日：2003-04-10

    申请人： Mario Dalko ,  Geneviéve Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    发明人： Mario Dalko ,  Geneviéve Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC分类号： A61K31/44

    CPC分类号： A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    摘要翻译： 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和的直链或支链C 1 -C 18烷基或芳基 该烷基或芳基任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代，或者R'和R“一起代表杂环，该组合物旨在诱导和/或刺激人的生长 角质纤维，如头发和睫毛，和/或减慢其损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS
    2.
    发明申请
    ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS 审中-公开
    吡啶二羧酸化合物的施用用于刺激或诱导人类激素纤维的生长和/或损害它们的损失

    公开(公告)号：US20100105741A1

    公开(公告)日：2010-04-29

    申请号：US12650777

    申请日：2009-12-31

    申请人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    发明人： Maria Dalko ,  Geneviève Loussouarn ,  Charles El Rawadi ,  Christophe Boulle ,  Bruno Bernard

    IPC分类号： A61K31/44

    CPC分类号： A61K8/4926 ,  A61K8/37 ,  A61K8/494 ,  A61K8/4953 ,  A61Q1/10 ,  A61Q7/00

    摘要： The invention relates to the use in a composition for caring for human hair or eyelashes of an effective amount of a pyridinedicarboxylic acid derivative of general formula (I) or of one of its salts, in which R1 and R2 represent, independently of one another, OH, OR′, —NH2, —NHR′ or —NR′R″, and R′ and R″ represent, independently of one another, a saturated or unsaturated and linear or branched C1-C18 alkyl radical or an aryl radical, this alkyl or aryl radical optionally being substituted by at least one OH, alkoxy, acyloxy, amino or alkylamino group, or R′ and R″ together represent a heterocycle, the composition being intended to induce and/or stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss; the invention also relates to a cosmetic treatment intended to stimulate the growth of human keratinous fibers, such as the hair and eyelashes, and/or slow down their loss.

    摘要翻译： 本发明涉及用于照护人发或睫毛的组合物中有效量的通式（I）的吡啶二羧酸衍生物或其盐之一，其中R 1和R 2彼此独立地表示， OH，OR'，-NH 2，-NHR'或-NR'R“，R'和R”彼此独立地表示饱和或不饱和和直链或支链的C 1 -C 18烷基或芳基， 任选被至少一个OH，烷氧基，酰氧基，氨基或烷基氨基取代的烷基或芳基，或R'和R“一起表示杂环，该组合物旨在诱导和/或刺激人角质纤维的生长， 如头发和睫毛，和/或减慢他们的损失; 本发明还涉及旨在刺激人角质纤维如头发和睫毛的生长和/或减缓其损失的美容治疗。

    Cosmetic use of a jasmonic acid derivative for treating the hair and the scalp
    6.
    发明授权
    Cosmetic use of a jasmonic acid derivative for treating the hair and the scalp 有权
    化妆品使用茉莉酸衍生物治疗头发和头皮

    公开(公告)号：US08679513B2

    公开(公告)日：2014-03-25

    申请号：US13382114

    申请日：2010-07-01

    申请人： Christophe Boulle ,  Maria Dalko

    发明人： Christophe Boulle ,  Maria Dalko

    IPC分类号： A61K8/02

    CPC分类号： A61K8/365 ,  A61Q1/10 ,  A61Q7/00

    摘要： The present invention relates to the cosmetic use of jasmonic acid derivatives of formula (I) in which: R1 represents a radical COOR3, R3 denoting a hydrogen atom or a C1-C4 alkyl radical, optionally substituted with one or more hydroxyl groups; R2 represents a linear saturated or unsaturated hydrocarbon-based radical containing from 1 to 18 carbon atoms, or a branched or cyclic saturated or unsaturated hydrocarbon-based radical containing from 3 to 18 carbon atoms; and also an optical isomer thereof and/or a corresponding salt thereof, in a composition for caring for and/or making up keratin fibers, in particular human keratin fibers, for the purpose of inducing and/or stimulating the growth of the keratin fibers and/or of halting their loss and/or increasing their density.

    摘要翻译： 本发明涉及式（I）茉莉酸衍生物的化妆品用途，其中：R1代表氢原子或C1-C4烷基的基团COOR3，R3表示任选被一个或多个羟基取代; R2表示含有1至18个碳原子的直链饱和或不饱和烃基，或含有3至18个碳原子的支链或环状饱和或不饱和烃基; 以及用于照顾和/或制备角蛋白纤维，特别是人角蛋白纤维的组合物中的旋光异构体和/或其相应的盐，用于诱导和/或刺激角蛋白纤维的生长，以及 /或停止其损失和/或增加其密度。

    Compositions comprising jasmonic acid derivatives and use of these derivatives
    7.
    发明授权
    Compositions comprising jasmonic acid derivatives and use of these derivatives 有权
    包含茉莉酸衍生物的组合物和这些衍生物的用途

    公开(公告)号：US08603502B2

    公开(公告)日：2013-12-10

    申请号：US10356551

    申请日：2003-02-03

    申请人： Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    发明人： Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    IPC分类号： A61K31/557

    CPC分类号： C07C69/732 ,  A61K8/345 ,  A61K8/365 ,  A61K8/44 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08 ,  C07C35/06 ,  C07C59/11 ,  C07C59/46 ,  C07C69/675 ,  C07C2601/08

    摘要： Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR′, —CONR′R″, —CH2OR′, —COR′, —CH2R′, —SO2OR′, —PO3R′R″ and —NHR′, wherein R′ and R″, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR′″, —OCOR′″, —SR′″, —SCOR′″, NR′″R″″, —NHCOR′″, halogen, —CN, —COOR′″ and —COR′″, wherein R′″ and R″″, which may be identical or different, are defined herein, as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.

    摘要翻译： 包含式（I）化合物及其相应盐的化妆品或药物组合物：其中：R1为选自-COOR'，-CONR'R“，-CHOOR'，-COR'，-CH2R'，-SO2OR的基团 '，-PO 3 R'R“和-NHR'，其中R'和R”可以相同或不同，在本文中定义; R 2选自包含1至18个碳原子的饱和和不饱和的，直链的，支链的和环状的烃基，其任选被1-5个相同或不同的选自-OR“，-OCOR” - ， - SR“'，-SCOR''，NR”'R“'， - NHCOR''，卤素，-CN，-COOR”和-COR“，其中R”'和 R“”可以相同或不同，并且这些化合物的用途，例如促进皮肤脱屑，刺激表皮更新和/或抵抗皮肤老化的迹象。

    Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening
    10.
    发明申请
    Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening 审中-公开
    用于促进和/或诱导和/或刺激角蛋白材料色素沉着和/或限制其脱色和/或增白的亚苄基-1,3-噻唑烷-2,4-二酮化合物

    公开(公告)号：US20070071699A1

    公开(公告)日：2007-03-29

    申请号：US11476051

    申请日：2006-06-28

    申请人： Christophe Boulle

    发明人： Christophe Boulle

    IPC分类号： A61K8/49 ,  A61K31/426

    CPC分类号： A61Q1/10 ,  A61K8/49 ,  A61K31/426 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/04

    摘要： The benzylidene-1,3-thiazolidine-2,4-dione compounds having the structural formula (I), or salt and/or solvate and/or isomer thereof: are useful active agents for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or preventing and/or limiting the depigmentation and/or bleaching thereof, particularly of human head hair, beard hair, moustache hair, eyelashes and eyebrows, and advantageously are active agents for preventing and/or limiting the canities of human keratin fibers.

    摘要翻译： 具有结构式（I）的亚苄基-1,3-噻唑烷-2,4-二酮化合物或其盐和/或其溶剂化物和/或异构体：用于促进和/或诱导和/或刺激 角蛋白材料的着色和/或防止和/或限制其脱色和/或漂白，特别是人头发，胡须毛，胡子毛，睫毛和眉毛，并且有利地是用于预防和/或限制 人角蛋白纤维。