Upregulation of RACK-1 in melanoma and its use as a marker
    1.
    发明授权
    Upregulation of RACK-1 in melanoma and its use as a marker 失效
    黑色素瘤中RACK-1的上调及其作为标记

    公开(公告)号:US08367348B2

    公开(公告)日:2013-02-05

    申请号:US12671415

    申请日:2008-07-28

    IPC分类号: G01N33/53

    摘要: The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocyte cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocyte cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

    摘要翻译: 本发明涉及用于诊断哺乳动物黑素瘤的方法,包括检测所述哺乳动物的黑素细胞细胞中RACK-1蛋白的过表达,以及从RACK-1蛋白的过表达中减少黑素瘤的存在。 本发明还涉及一种用于确定哺乳动物黑素细胞细胞的肿瘤状态的方法,其包括检测黑素细胞细胞中RACK-1蛋白的过度表达,以及所述细胞的肿瘤状态从过表达 RACK-1蛋白。

    UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
    2.
    发明申请
    UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER 有权
    作为一个标记用于MELANOMA中的RACK-1和其使用的升级

    公开(公告)号:US20110045475A1

    公开(公告)日:2011-02-24

    申请号:US12830775

    申请日:2010-07-06

    IPC分类号: C12Q1/68 C12Q1/02 G01N33/53

    CPC分类号: G01N33/5743 G01N2333/705

    摘要: The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

    摘要翻译: 本发明涉及一种用于诊断哺乳动物黑素瘤的方法,包括检测所述哺乳动物的黑素细胞中RACK-1蛋白的过表达,以及从RACK-1蛋白的过表达中减少黑素瘤的存在。 本发明还涉及一种用于确定哺乳动物黑素细胞细胞的肿瘤状态的方法,包括检测黑素细胞中RACK-1蛋白的过度表达,以及所述细胞的肿瘤状态从过表达 RACK-1蛋白。

    Upregulation of rack-1 in melanoma and its use as a marker
    3.
    发明授权
    Upregulation of rack-1 in melanoma and its use as a marker 有权
    上调黑色素瘤中的架-1,并将其用作标记物

    公开(公告)号:US08247182B2

    公开(公告)日:2012-08-21

    申请号:US12830775

    申请日:2010-07-06

    IPC分类号: G01N33/53

    CPC分类号: G01N33/5743 G01N2333/705

    摘要: The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

    摘要翻译: 本发明涉及一种用于诊断哺乳动物黑素瘤的方法,包括检测所述哺乳动物的黑素细胞中RACK-1蛋白的过表达,以及从RACK-1蛋白的过表达中减少黑素瘤的存在。 本发明还涉及一种用于确定哺乳动物黑素细胞细胞的肿瘤状态的方法,包括检测黑素细胞中RACK-1蛋白的过度表达,以及所述细胞的肿瘤状态从过表达 RACK-1蛋白。

    UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
    5.
    发明申请
    UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER 审中-公开
    作为一个标记用于MELANOMA中的RACK-1和其使用的升级

    公开(公告)号:US20090098535A1

    公开(公告)日:2009-04-16

    申请号:US11831128

    申请日:2007-07-31

    IPC分类号: C12Q1/68 C12Q1/02 G01N33/574

    CPC分类号: G01N33/5743 G01N2333/705

    摘要: The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

    摘要翻译: 本发明涉及一种用于诊断哺乳动物黑素瘤的方法,包括检测所述哺乳动物的黑素细胞中RACK-1蛋白的过表达,以及从RACK-1蛋白的过表达中减少黑素瘤的存在。 本发明还涉及一种用于确定哺乳动物黑素细胞细胞的肿瘤状态的方法,包括检测黑素细胞中RACK-1蛋白的过度表达,以及所述细胞的肿瘤状态从过表达 RACK-1蛋白。