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1.发明授权Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof 有权用于释放包含化学氧化物的产品的方法，用于检测所述产品的方法及其用途公开(公告)号：US08741593B2
公开(公告)日：2014-06-03
申请号：US11601649
申请日：2006-11-20
IPC分类号： C12Q1/26 , C12Q1/00 , G01N33/00 , C12P13/00 , C12P11/00 , C12P7/00 , C12P7/24 , C12P7/26 , C12N13/00
CPC分类号： C07D407/12 , C07D311/16 , C12Q1/26 , C12Q1/34 , C12Q1/37 , C12Q2326/00 , C12Q2334/00 , C12Q2334/20 , G01N2333/918
摘要： This invention has as its object a method for releasing a product by subjecting a compound of Formula (II′): R′7R′8(HX)C1-C2(YH)R′9R′10 to a chemical oxidation that cleaves the bond C1-C2 to obtain the product. In the compound of Formula (II′): R′7 to R′10, which are identical or different, correspond to a hydrogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted functional group; X and Y, which are identical or different, are an oxygen atom, a sulfur atom, or an amine of Formula —NR11R12, wherein R11 is a hydrogen atom, an alkyl group, or a substituted or unsubstituted aryl group, and R12 is not a hydrogen atom. The invention also has as its object a method for releasing a product that comprises, before the chemical oxidation stage, a first step for preparing the compound of Formula (II′). The released product can be a volatile molecule or an active substance or else a specific product. The invention also relates to a method for detecting the released product as well as its applications, in particular for detecting catalytic or enzymatic activities.
摘要翻译： 本发明的目的是通过使式（II'）的化合物：R'7R'8（HX）C1-C2（YH）R'9R'10进行切割键的化学氧化来释放产物的方法 C1-C2获得产品。 在式（II'）的化合物中：相同或不同的R'7至R'10对应于氢原子，取代或未取代的烷基或取代或未取代的官能团; X和Y相同或不同，是式-NR11R12的氧原子，硫原子或胺，其中R11是氢原子，烷基或取代或未取代的芳基，R12不是 氢原子。 本发明的目的还有一种释放产品的方法，该方法包括在化学氧化阶段之前制备式（II'）化合物的第一步骤。 释放的产物可以是挥发性分子或活性物质或特定产物。 本发明还涉及用于检测释放产物及其应用的方法，特别是用于检测催化或酶活性。
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2.发明申请Method for releasing a product comprising chemical oxidation, method for detecting said product and uses thereof 有权用于释放包含化学氧化物的产品的方法，用于检测所述产品的方法及其用途公开(公告)号：US20070099257A1
公开(公告)日：2007-05-03
申请号：US11601649
申请日：2006-11-20
IPC分类号： C12Q1/26
CPC分类号： C07D407/12 , C07D311/16 , C12Q1/26 , C12Q1/34 , C12Q1/37 , C12Q2326/00 , C12Q2334/00 , C12Q2334/20 , G01N2333/918
摘要： This invention has as its object a method for releasing a product by subjecting a compound of Formula (II′): R′7R′8(HX)C1-C2(YH)R′9R′10 to a chemical oxidation that cleaves the bond C1-C2 to obtain the product. In the compound of Formula (II′): R′7 to R′10, which are identical or different, correspond to a hydrogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted functional group; X and Y, which are identical or different, are an oxygen atom, a sulfur atom, or an amine of Formula —NR11R12, wherein R11 is a hydrogen atom, an alkyl group, or a substituted or unsubstituted aryl group, and R12 is not a hydrogen atom. The invention also has as its object a method for releasing a product that comprises, before the chemical oxidation stage, a first step for preparing the compound of Formula (II′). The released product can be a volatile molecule or an active substance or else a specific product. The invention also relates to a method for detecting the released product as well as its applications, in particular for detecting catalytic or enzymatic activities.
摘要翻译： 本发明的目的是通过使式（II'）的化合物：R'，R“8（HX）C（C） （YH）R'9 R 10与化学氧化反应，其切割键C 1 C 2以获得产物。 在式（II'）的化合物中：R'7至R'10相同或不同，相当于氢原子，取代或未取代的烷基 ，或取代或未取代的官能团; X和Y相同或不同，是氧原子，硫原子或式-NR 11 R 12的胺，其中R 11 R 2是氢原子，烷基或取代或未取代的芳基，R 12不是氢原子。 本发明的目的还有一种释放产品的方法，该方法包括在化学氧化阶段之前制备式（II'）化合物的第一步骤。 释放的产物可以是挥发性分子或活性物质或特定产物。 本发明还涉及用于检测释放产物及其应用的方法，特别是用于检测催化或酶活性。
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公开(公告)号：US20050112644A1
公开(公告)日：2005-05-26
申请号：US10954826
申请日：2004-09-30
申请人： Burghard Gruning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
发明人： Burghard Gruning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
CPC分类号： C12N9/14
摘要： The present invention relates to a newly identified hydrolase from thermophilic microorganisms having thermostable properties, and more specifically, to a novel thermostable hydrolase showing high activity at high temperatures.
摘要翻译： 本发明涉及具有热稳定性质的新鉴定的嗜热微生物水解酶，更具体地说，涉及一种在高温下显示高活性的新型热稳定水解酶。
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公开(公告)号：US07595181B2
公开(公告)日：2009-09-29
申请号：US10954826
申请日：2004-09-30
申请人： Burghard Grüning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
发明人： Burghard Grüning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
IPC分类号： C12N9/18 , C07K14/195 , C12P21/02 , C12P7/64
CPC分类号： C12N9/14
摘要： The present invention relates to a newly identified hydrolase from thermophilic microorganisms having thermostable properties, and more specifically, to a novel thermostable hydrolase showing high activity at high temperatures.
摘要翻译： 本发明涉及具有热稳定性质的新鉴定的嗜热微生物水解酶，更具体地说，涉及一种在高温下显示高活性的新型热稳定水解酶。
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5.发明申请Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase 审中-公开使用热稳定酯酶生产羧酸和碳酸衍生物公开(公告)号：US20060008887A1
公开(公告)日：2006-01-12
申请号：US10955053
申请日：2004-09-30
申请人： Burghard Gruning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
发明人： Burghard Gruning , Geoffrey Hills , Thomas Veit , Christian Weitemeyer , Olivier Favre-Bulle , Fabrice Lefevre , Hong-Khanh Nguyen , Gilles Ravot
IPC分类号： C12P7/64
CPC分类号： C12P7/6418 , C12P7/42 , C12P7/62 , C12P7/625 , C12P7/6436 , C12P9/00 , C12P11/00 , C12P13/02 , C12P17/10 , C12P17/12
摘要： The present invention relates to processes for the production of acyl compounds using an esterase having thermostable properties, and to products of such processes.
摘要翻译： 本发明涉及使用具有热稳定性的酯酶制备酰基化合物的方法以及这些方法的产物。
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