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公开(公告)号：US09107843B2
公开(公告)日：2015-08-18
申请号：US13304195
申请日：2011-11-23
Applicant: Jean-Thierry Simonnet , Anil Shah , Susan Halpern
Inventor： Jean-Thierry Simonnet , Anil Shah , Susan Halpern
Abstract: The disclosure relates to sunscreen compositions having a synergistic combination of ultraviolet light (UV) filtering agents that provide a high sun protection factor (SPF). Compositions according to the disclosure have high SPF values without requiring high overall amounts of UV filtering agents. Furthermore, the disclosure relates to methods of using the described compositions for protecting keratinous substances such as skin and hair from UV radiation.
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2.发明授权Vectorization of dsRNA by cationic particles and use of same on a skin model 有权通过阳离子颗粒对dsRNA进行向量化，并在皮肤模型上使用它们公开(公告)号：US09095630B2
公开(公告)日：2015-08-04
申请号：US11436775
申请日：2006-05-19
Applicant: Christine Collin-Djangone , Jean-Thierry Simonnet
Inventor： Christine Collin-Djangone , Jean-Thierry Simonnet
IPC: A61K48/00 , A61K47/48 , A61K31/713 , B82Y5/00 , C12N15/113
CPC classification number: A61K47/488 , A61K31/713 , A61K47/6907 , A61K47/6911 , B82Y5/00 , C12N15/113
Abstract: The present invention relates to vectorization of double stranded RNA oligonucleotides by cationic particles chosen from among surfactant micelles, block or non-block polymer micelles, cationic liposomes and niosomes, cationic oleosomes and cationic nanoemulsions, as well as from among cationic organic or inorganic particles and nanocapsules, and to the use of compositions comprising the association of at least one dsRNA and at least one cationic particle on skin models.
Abstract translation: 本发明涉及通过选自表面活性剂胶束，嵌段或非嵌段聚合物胶束，阳离子脂质体和niosomes，阳离子油质体和阳离子纳米乳液中的阳离子颗粒以及阳离子有机或无机颗粒和 纳米胶囊，以及使用包含至少一种dsRNA和至少一种阳离子颗粒在皮肤模型上缔合的组合物。
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3.发明授权Porous particles loaded with cosmetically or pharmaceutically active compounds 有权加载化妆品或药物活性化合物的多孔颗粒公开(公告)号：US08507006B2
公开(公告)日：2013-08-13
申请号：US13311080
申请日：2011-12-05
Applicant: Jean-Thierry Simonnet , Bruno Biatry , Didier Saint-Leger
Inventor： Jean-Thierry Simonnet , Bruno Biatry , Didier Saint-Leger
CPC classification number: A61K8/88 , A61K8/0279 , A61K8/25 , A61K2800/412 , A61K2800/56 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q19/00
Abstract: Individualized porous particles having a volume-average diameter of less than or equal to 10 μm and a specific surface area of greater than or equal to 1 m2/g, and that include at least one cosmetically or pharmaceutically active compound present at least inside the particles.
Abstract translation: 具有体积平均直径小于或等于10μm并且比表面积大于或等于1m 2 / g的个体化多孔颗粒，并且包括至少一种至少存在于颗粒内部的美容或药学活性化合物 。
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4.发明申请公开(公告)号：US20130129650A1
公开(公告)日：2013-05-23
申请号：US13304202
申请日：2011-11-23
Applicant: Jean-Thierry Simonnet , Anil Shah
Inventor： Jean-Thierry Simonnet , Anil Shah
Abstract: The disclosure relates to sunscreen compositions having a synergistic combination of ultraviolet light (UV) filtering agents that provide a high sun protection factor (SPF). Compositions according to the disclosure have high SPF values without requiring high overall amounts of UV filtering agents, and without requiring the use of oxybenzone. Furthermore, the disclosure relates to methods of using the described compositions for protecting keratinous substances such as skin and hair from UV radiation.
Abstract translation: 本公开涉及具有提供高防晒因子（SPF）的紫外线（UV）过滤剂的协同组合的防晒组合物。 根据本公开的组合物具有高的SPF值，而不需要高量的UV过滤剂，并且不需要使用羟基苯酮。 此外，本公开涉及使用所述组合物从紫外线辐射中保护角质物质如皮肤和毛发的方法。
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5.发明申请METHODS OF PHOTOPROTECTING A MATERIAL AGAINST SOLAR UV RADIATION USING PHOTONIC PARTICLES; COMPOSITIONS 审中-公开使用光子粒子对太阳紫外线辐射进行光电保护的材料的方法; 组合物公开(公告)号：US20120244202A1
公开(公告)日：2012-09-27
申请号：US13500036
申请日：2010-10-12
Applicant: Jean-Thierry Simonnet , Karine Lucet-Levannier
Inventor： Jean-Thierry Simonnet , Karine Lucet-Levannier
CPC classification number: C09D11/00 , A61K8/0275 , A61K8/0283 , A61K8/8152 , A61K2800/26 , A61K2800/412 , A61K2800/437 , A61Q17/04 , C03C17/007 , C03C2217/48 , C08K3/014 , C09D7/62 , C09D7/69 , D06M11/79 , D06M23/08 , D06M23/12 , D06M2200/25
Abstract: A method of photoprotecting a material against solar UV radiation by treating the material using a composition having a dispersion of photonic particles with a mean size in the range 1 μm to 500 μm, each having a diffracting arrangement of monodisperse nanoparticles or voids, the diffraction spectrum of the arrangement including a first order reflection peak in the wavelength range 250 nm to 400 nm, or by integrating the dispersion of photonic particles into the material.
Abstract translation: 通过使用具有1μm〜500μm的平均尺寸的光子粒子的分散体的组合物处理材料来对抗太阳紫外线辐射光保护材料的方法，每个具有单分散纳米颗粒或空隙的衍射布置，衍射光谱 包括在250nm至400nm的波长范围内的一级反射峰，或通过将光子粒子的分散积分入材料中。
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Patent Agency Ranking
公开(公告)号：US20120156269A1
公开(公告)日：2012-06-21
申请号：US13382077
申请日：2010-07-01
Applicant: Jean-Thierry Simonnet , Roxane Gavillon
Inventor： Jean-Thierry Simonnet , Roxane Gavillon
CPC classification number: A61Q1/02 , A61K8/11 , A61K8/25 , A61K8/585 , A61K8/891 , A61K8/895 , A61K2800/412 , A61K2800/95 , A61Q5/02 , A61Q19/00
Abstract: The invention relates to a cosmetic composition comprising, in a physiologically acceptable medium, at least one organopolysiloxane compound X having at least two alkenyl unsaturated groups, at least one organohydrogensiloxane compound Y and at least one hydrosilylation catalyst, and said compounds X and Y reacting together via a hydrosilylation reaction in the presence of the catalyst, at least one compound among the compounds X and Y being present in said composition in a form encapsulated in silica shell microcapsules, said catalyst being associated with said encapsulated compound X and/or Y or being encapsulated separately, the microcapsules being in suspension in an aqueous phase. Application for the cosmetic care and/or making up of keratin materials.
Abstract translation: 本发明涉及一种化妆品组合物，其在生理上可接受的介质中包含至少一种具有至少两个烯基不饱和基团的有机聚硅氧烷化合物X，至少一种有机氢硅氧烷化合物Y和至少一种氢化硅烷化催化剂，并且所述化合物X和Y反应在一起 通过在催化剂存在下的氢化硅烷化反应，化合物X和Y中的至少一种化合物以包封在二氧化硅壳微胶囊中的形式存在于所述组合物中，所述催化剂与所述包封的化合物X和/或Y相关联或 单独包封，微胶囊在水相中悬浮。 用于化妆品护理和/或组合角蛋白材料的应用。
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公开(公告)号：US20110110989A1
公开(公告)日：2011-05-12
申请号：US12866463
申请日：2009-02-11
Applicant: Jean-Thierry Simonnet , Florence L'Alloret , Lydie Bressy , Zohra Moujahed
Inventor： Jean-Thierry Simonnet , Florence L'Alloret , Lydie Bressy , Zohra Moujahed
IPC: A61K8/02 , A61K8/368 , A61K8/64 , A61K8/365 , A61K8/96 , A61K8/66 , A61K8/97 , A61K8/67 , A61K8/99 , A61Q17/04 , A61Q19/00
CPC classification number: A61K8/06 , A61K8/062 , A61K8/8147 , A61K8/8152 , A61K8/8158 , A61K8/87 , A61K8/90 , A61K2800/262 , A61Q1/14 , A61Q19/00
Abstract: The present patent application relates to a composition for topical application in the form of an oil-in-water emulsion comprising an oily phase dispersed in an aqueous phase, characterized in that it comprises at least one noncrosslinked amphiphilic polymer, the globules of the said emulsion exhibiting a mean size ranging from 15 to 500 microns and the oily phase being present in an amount of less than 35% by weight, with respect to the total weight of the composition.
Abstract translation: 本专利申请涉及以水包油乳状液形式局部施用的组合物，其包含分散在水相中的油相，其特征在于其包含至少一种非交联的两亲性聚合物，所述乳液的小球 表现出15至500微米的平均尺寸，相对于组合物的总重量，油相的存在量小于35重量％。
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8.发明申请公开(公告)号：US20100203004A1
公开(公告)日：2010-08-12
申请号：US12676541
申请日：2008-10-28
Applicant: Jean-Thierry Simonnet , Guillaume Cassin
Inventor： Jean-Thierry Simonnet , Guillaume Cassin
CPC classification number: A61Q19/08 , A61K8/25 , A61K8/645 , A61K8/8152 , A61K8/87
Abstract: The invention relates to a cosmetic composition comprising, in a physiologically acceptable medium, a skin-tensioning agent and an acrylic polymer containing a group of phosphorylcholine type. The invention also relates to a cosmetic skincare process, more particularly for facial skin, in particular wrinkled skin, comprising the application of the composition to the skin.
Abstract translation: 本发明涉及一种化妆品组合物，其在生理上可接受的介质中包含皮肤张力剂和含有一组磷酸胆碱型的丙烯酸类聚合物。 本发明还涉及一种化妆品护肤方法，更具体地涉及面部皮肤，特别是皱纹皮肤，包括将组合物施用于皮肤。
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公开(公告)号：US20090317430A1
公开(公告)日：2009-12-24
申请号：US12438218
申请日：2007-06-29
Applicant: Guillaume Cassin , Jean-Thierry Simonnet
Inventor： Guillaume Cassin , Jean-Thierry Simonnet
CPC classification number: A61K8/8152 , A61K8/0245 , A61K8/466 , A61K8/891 , A61K8/893 , A61K8/895 , A61K8/897 , A61K8/898 , A61K8/899 , A61K2800/412 , A61K2800/42 , A61Q1/02 , A61Q19/02
Abstract: Cosmetic composition for lightening or unifying the complexion The present invention relates to a composition comprising, in a physiologically acceptable medium, concave or annular particles, especially in the form of hollow sphere portions, the said particles comprising a matrix that is coloured in the bulk.
Abstract translation: 用于减轻或统一肤色的化妆品组合物本发明涉及一种组合物，其在生理上可接受的介质中包含凹形或环形颗粒，特别是中空球形部分的形式，所述颗粒包含在本体中着色的基质。
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10.发明申请Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) 审中-公开至少一种双链RNA寡核苷酸（dsRNA）的局部给药公开(公告)号：US20090117063A1
公开(公告)日：2009-05-07
申请号：US12007387
申请日：2008-01-09
Applicant: Albert Duranton , Christine Collin-Djangone , Francis Pruche , Jean-Thierry Simonnet
Inventor： Albert Duranton , Christine Collin-Djangone , Francis Pruche , Jean-Thierry Simonnet
IPC: A61K31/7088 , A61K31/713 , A61K8/72
CPC classification number: A61Q19/007 , A61K8/606 , A61K31/7088 , A61Q7/00 , A61Q19/00 , A61Q19/02 , A61Q19/08 , C12N2310/13
Abstract: Expression of a messenger RNA which encodes a protein which is expressed by differentiated cells, notably the cells of the skin or appendages thereof, is inhibited by topically administering to said differentiated cells a thus effective amount of at least one double-stranded RNA oligonucleotide, formulated into a topically applicable, physiologically acceptable medium therefor; such regime or regimen is useful for treating a variety of afflictions or conditions, e.g., combating the signs of skin aging, stimulating hair growth or retarding loss thereof, inhibiting cellular proliferation and/or differentiation, etc.
Abstract translation: 编码由分化细胞，特别是皮肤细胞或其附属物表达的蛋白质的信使RNA的表达通过向所述分化的细胞局部给予如此有效量的至少一种双链RNA寡核苷酸而被抑制，所述双链RNA寡核苷酸被配制 成为局部适用的生理上可接受的介质; 这种制度或方案可用于治疗多种疾病或病症，例如抵抗皮肤老化，刺激毛发生长或延缓其损失，抑制细胞增殖和/或分化等症状。
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