-
1.发明授权Polyepitopic protein fragments of the E6 and E7 proteins of HPV, their production and their use particularly in vaccination 有权HPV的E6和E7蛋白的多表位蛋白片段，其生产及其在疫苗接种中的用途公开(公告)号：US07288258B2
公开(公告)日：2007-10-30
申请号：US10858384
申请日：2004-06-02
申请人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gerard Guillet , Francine Connan , Estelle Ferries
发明人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gerard Guillet , Francine Connan , Estelle Ferries
IPC分类号： A16K39/12
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2710/20022 , C12N2740/16322
摘要： Polyepitopic peptides of E6 and E7 proteins of Human Papillomavirus, their production, and methods of treating pathologies in which a polyepitopic peptide of the E6 and E7 protein of Human Papillomavirus is recognized by the cellular immune system.
摘要翻译： 人乳头瘤病毒的E6和E7蛋白质的多表位肽，其生产方法和治疗人乳头瘤病毒的E6和E7蛋白的多表位肽的细胞免疫系统的病理学方法。
-
2.发明申请POLYEPITOPIC PROTEIN FRAGMENTS OF THE E6 AND E7 PROTEINS OF HPV, THEIR PRODUCTION AND THEIR USE PARTICULARLY IN VACCINATION 审中-公开HPV6的E6和E7蛋白质的多肽蛋白质片段，其生产及其特异性用于疫苗接种公开(公告)号：US20080248044A1
公开(公告)日：2008-10-09
申请号：US11859320
申请日：2007-09-21
申请人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gerard Guillet , Francine Connan , Estelle Ferries
发明人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gerard Guillet , Francine Connan , Estelle Ferries
IPC分类号： A61K39/395 , C07K7/08 , C07K14/00 , C07H21/00 , C07K16/00 , A61P37/02 , A61K38/10 , A61K38/16 , A61K39/12 , A61K31/7052
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2710/20022 , C12N2740/16322
摘要： Polyepitopic peptides of E6 and E7 proteins of Human Papillomavirus, their production, and methods of treating pathologies in which a polyepitopic peptide of the E6 and E7 protein of Human Papillomavirus is recognized by the cellular immune system.
摘要翻译： 人乳头瘤病毒的E6和E7蛋白质的多表位肽，其生产方法和治疗人乳头瘤病毒的E6和E7蛋白的多表位肽的细胞免疫系统的病理学方法。
-
3.发明授权Polyepitopic proteinic fragments of the E6 and E7 HPV proteins, production and use thereof in vaccines 有权E6和E7 HPV蛋白的多表位蛋白质片段，其在疫苗中的生产和应用公开(公告)号：US06783763B1
公开(公告)日：2004-08-31
申请号：US09980523
申请日：2002-04-29
申请人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gérard Guillet , Francine Connan , Estelle Ferries
发明人： Jeannine Choppin , Isabelle Bourgault Villada , Jean-Gérard Guillet , Francine Connan , Estelle Ferries
IPC分类号： A61K3912
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2710/20022 , C12N2740/16322
摘要： Polyepitopic fragments of the E6 or E7 protein of HPV comprise a peptide sequence of about 15 to 30 amino acids. This peptide sequence contains amino acid sequences of at least 3 different epitopes binding stably to HLA molecules of identical or different type, when these epitopes are obtained by enzymatic degradation of the peptide sequence, particularly in the proteasome, such that at least 4 HLA molecules of different types bind to these epitopes. These 4 HLA molecules are selected from among those of types A1, A2, A3, A11, A24, A29, B7, B8, B18, B27, B35, B44, B51 and B62.
摘要翻译： HPV的E6或E7蛋白的多表位片段包含约15至30个氨基酸的肽序列。 当通过肽序列的酶降解，特别是在蛋白酶体中获得这些表位时，该肽序列含有至少3种与相同或不同类型的HLA分子稳定结合的表位的氨基酸序列，使得至少4个HLA分子 不同的类型绑定到这些表位。 这4种HLA分子选自A1，A2，A3，A11，A24，A29，B7，B8，B18，B27，B35，B44，B51和B62。
-
4.发明申请Polyepitopic protein fragments of the E6 and E7 proteins of HPV, their production and their use particularly in vaccination 有权HPV的E6和E7蛋白的多表位蛋白片段，其生产及其在疫苗接种中的用途公开(公告)号：US20050033025A1
公开(公告)日：2005-02-10
申请号：US10858384
申请日：2004-06-02
IPC分类号： A61K38/00 , A61K39/00 , A61P31/18 , C07K14/025 , C07K14/16 , C12N15/12 , C12N15/33 , C12N15/37 , C12Q1/70 , C07H21/04
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2710/20022 , C12N2740/16322
摘要： Polyepitopic peptides of E6 and E7 proteins of Human Papillomavirus, their production, and methods of treating pathologies in which a polyepitopic peptide of the E6 and E7 protein of Human Papillomavirus is recognized by the cellular immune system.
摘要翻译： 人乳头瘤病毒的E6和E7蛋白质的多表位肽，其生产方法和治疗人乳头瘤病毒的E6和E7蛋白的多表位肽的细胞免疫系统的病理学方法。
-
-
-
搜索结果
4 条记录 (耗时 0.023 秒)
