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1.
公开(公告)号:US20100331204A1
公开(公告)日:2010-12-30
申请号:US12695447
申请日:2010-01-28
申请人: Jeff Jeddeloh , Todd Richmond , Matthew Rodesch , Daniel Gerhardt , Paul Marrione , Thomas Albert
发明人: Jeff Jeddeloh , Todd Richmond , Matthew Rodesch , Daniel Gerhardt , Paul Marrione , Thomas Albert
CPC分类号: C12Q1/6806 , C12Q1/6809 , C12Q1/6837 , C12Q2565/515 , C12Q2539/101 , C12Q2563/131 , C12Q2537/149
摘要: The present invention provides methods and systems for targeted nucleic acid sequence enrichment in a sample. In particular, the present invention provides for enriching for targeted nucleic acid sequences during hybridizations in hybridization assays by first depleting non-target nucleic acid sequences.
摘要翻译: 本发明提供了样品中目标核酸序列富集的方法和系统。 特别地,本发明提供了通过首先消耗非靶核酸序列在杂交测定中的杂交期间富集靶向的核酸序列。
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公开(公告)号:US20100167952A1
公开(公告)日:2010-07-01
申请号:US12553251
申请日:2009-09-03
申请人: Thomas Albert , Jeff Jeddeloh , Bradley Swanson
发明人: Thomas Albert , Jeff Jeddeloh , Bradley Swanson
CPC分类号: C12Q1/6837 , C12Q1/6832 , C12Q2537/163 , C12Q2525/191 , C12Q2525/151 , C12Q2549/126
摘要: The present invention provides for compositions, methods and systems for targeted sequence enrichment. In particular, the present invention provides for enriching for targeted nucleic acid sequences during hybridizations in microarray assays by suppressing secondary capture of non-target nucleic acid sequences.
摘要翻译: 本发明提供用于靶向序列富集的组合物,方法和系统。 特别地,本发明提供了通过抑制非靶核酸序列的二次捕获在微阵列测定中杂交期间富集目标核酸序列。
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