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公开(公告)号:US20050043808A1
公开(公告)日:2005-02-24
申请号:US10935041
申请日:2004-09-07
IPC分类号: A61B1/00 , A61B17/00 , A61B17/16 , A61B17/17 , A61B17/88 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2/42 , A61F2/44 , A61F2/46 , A61F2/82 , A61L27/18 , A61L29/04 , A61L29/06 , C08G18/10 , C08G18/48 , C08G18/69
CPC分类号: A61B17/1739 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/1675 , A61B17/1764 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/30235 , A61F2002/30583 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/4854 , C08G18/69 , C08L75/04 , C08L83/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable composition can be delivered using minimally invasive means to a tissue site and there fully cured provide a permanent and biocompatible prosthesis for repair of the tissue site. Further provided are a mold apparatus, e.g., in the form of a balloon or tubular cavity, for receiving a biomaterial composition, and a method for delivering and filling the mold apparatus with a curable composition in situ to provide a prosthesis for tissue repair.
摘要翻译: 一种用于修复组织部位的方法和相关组合物和装置。 该方法包括使用可固化的聚氨酯生物材料组合物,其具有适于在使用时混合的多个部分,以提供可流动的组合物并开始固化。 可流动组合物可以使用微创手段递送到组织部位,并且完全固化提供用于修复组织部位的永久性和生物相容性假体。 还提供了一种用于接收生物材料组合物的气球或管状空腔形式的模具装置,以及用于在原位地递送和填充具有可固化组合物的模具装置以提供用于组织修复的假体的方法。
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公开(公告)号:US20060111726A1
公开(公告)日:2006-05-25
申请号:US10520979
申请日:2003-07-10
申请人: Jeffrey Felt , Mark Rydell , david Griffin , Paul Buscemi , Alexander Arsenyev
发明人: Jeffrey Felt , Mark Rydell , david Griffin , Paul Buscemi , Alexander Arsenyev
IPC分类号: A61F5/00
CPC分类号: A61F2/4657 , A61B17/00234 , A61B17/1659 , A61B17/1675 , A61B17/70 , A61B90/06 , A61B2017/00557 , A61B2090/061 , A61F2/30721 , A61F2/3872 , A61F2/4684 , A61F2002/30133 , A61F2002/30616 , A61F2002/30708 , A61F2002/30713 , A61F2002/30714 , A61F2002/30754 , A61F2002/3895 , A61F2002/4623 , A61F2002/4635 , A61F2002/4658 , A61F2002/4661 , A61F2002/4662 , A61F2230/0015 , A61F2250/0084 , A61F2250/0087 , A61F2250/0089
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed components adapted for insertion and placement into the body and at the joint site. The system includes a method and related components and/or devices in the form of a kit that can be used to provide or perform some or all of the steps of: a) preparing a joint to receive an implant, b) determining an appropriate implant size for a particular joint, c) determining an appropriate implant thickness, d) inserting the implant into the joint, and/or e) securing the implant within the joint to a desired extent. One or more of the various components and devices, including optionally one or more implants themselves, can be provided or packaged separately or in varying desired combinations and subcombinations to provide a kit of this invention. In turn, a kit can include, or be used in combination with, one or more corresponding devices or components that will already exist in the surgical suite, and that can optionally be sterilized for re-use in subsequent procedures. The selection and use of components, devices and/or implants within a kit of this invention is facilitated by the coordination of various features in the manner described, including appearance, size and configuration.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成形的部件,适于插入和放置在身体和关节部位。 该系统包括可以用于提供或执行以下一些或全部步骤的套件形式的方法和相关组件和/或装置:a)制备接头以接收植入物,b)确定合适的植入物 特定关节的尺寸,c)确定合适的植入物厚度,d)将植入物插入关节中,和/或e)将植入物固定在关节内达到期望的程度。 各种组件和装置中的一种或多种,包括任选的一种或多种植入物本身可以单独地或以不同的所需组合和亚组合提供或包装以提供本发明的试剂盒。 反过来,试剂盒可以包括或者与已经存在于外科手术套件中的一个或多个相应的装置或部件组合使用,并且可以任选地在后续程序中进行消毒以再次使用。 通过以所描述的方式(包括外观,尺寸和配置)协调各种特征,促进本发明的试剂盒内的组分,装置和/或植入物的选择和使用。
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公开(公告)号:US20070038300A1
公开(公告)日:2007-02-15
申请号:US11277887
申请日:2006-03-29
申请人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
发明人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A system for repairing an intervertebral disc by delivering and curing a biomaterial in situ within the disc. The system includes both a device, having an insertable balloon and related lumen, controls and adapters, as well as an in situ curable biomaterial (and related biomaterial delivery means). The system can allow the doctor to determine a suitable endpoint for biomaterial delivery, by controlling distraction and/or biomaterial delivery pressure, and in turn, to deliver a desired quantity of biomaterial to the balloon in order to achieve improved polymer cure and implant characteristics. Also provided is a related method for repairing an intervertebral disc by using such a system to deliver and cure the biomaterial in situ. The system can be used to implant a prosthetic total disc, or a prosthetic disc nucleus in a manner that leaves the surrounding disc tissue substantially intact.
摘要翻译: 一种通过在盘内原位递送和固化生物材料来修复椎间盘的系统。 该系统包括具有可插入球囊和相关内腔的装置,对照和适配器,以及原位可固化生物材料(和相关的生物材料递送装置)。 该系统可以允许医生通过控制牵引和/或生物材料输送压力来确定用于生物材料递送的合适的终点,并且反过来,将气体中所需量的生物材料输送到气囊中,以实现改进的聚合物固化和植入特征。 还提供了一种通过使用这种系统来原位递送和固化生物材料来修复椎间盘的相关方法。 该系统可以用于以使得周围的盘组织基本上完整的方式植入假体总盘或假体椎间盘细胞核。
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公开(公告)号:US20060253200A1
公开(公告)日:2006-11-09
申请号:US11428120
申请日:2006-06-30
申请人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
发明人: Qi-Bin Bao , Robert Hudgins , Jeffrey Felt , Alexander Arsenyev , Hansen Yuan
IPC分类号: A61F2/44
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A method of treating a diseased or damaged intervertebral disc having a nucleus pulposus and an annulus. The method includes the steps of accessing and preparing the intervertebral disc for receipt of the biomaterial by removing at least a portion of the nucleus pulposus to create a nuclear cavity. A quantity of the curable biomaterial is delivered under pressure to the nuclear cavity. The delivered biomaterial is at least partially cured in such a manner to retain it in the nuclear cavity. The at least partially cured biomaterial is contoured to achieve a desired conformation approximating that of the nuclear cavity.
摘要翻译: 一种治疗患有或受损的具有髓核和环的椎间盘的方法。 该方法包括以下步骤:通过去除髓核的至少一部分以产生核腔来获取和准备用于接收生物材料的椎间盘。 一定量的可固化生物材料在压力下输送到核腔。 递送的生物材料至少部分地固化,以将其保持在核腔中。 所述至少部分固化的生物材料的轮廓是实现与核腔近似的所需构型。
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公开(公告)号:US08100979B2
公开(公告)日:2012-01-24
申请号:US12479402
申请日:2009-06-05
IPC分类号: A61F2/44
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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6.
公开(公告)号:US20090112221A1
公开(公告)日:2009-04-30
申请号:US12015359
申请日:2008-01-16
CPC分类号: A61F2/4657 , A61F2002/30092 , A61F2002/30583 , A61F2002/444 , A61F2002/4658 , A61F2002/4663 , A61F2210/0014 , A61F2210/0085
摘要: A method and system of evaluating the geometry of the nuclear cavity within the annulus. A three-dimensional mold of the nuclear cavity is created. The three-dimensional mold is preferably removed from the nuclear cavity. The three-dimensional mold can be used for qualitative and quantitative analysis of the nuclear cavity.
摘要翻译: 评估环空中核腔几何的方法和系统。 创建了核腔的三维模具。 优选从核腔去除三维模具。 三维模具可用于核腔的定性和定量分析。
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公开(公告)号:US6140452A
公开(公告)日:2000-10-31
申请号:US195328
申请日:1998-11-18
IPC分类号: A61B1/00 , A61B17/00 , A61B17/16 , A61B17/17 , A61B17/88 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/32 , A61F2/38 , A61F2/40 , A61F2/42 , A61F2/44 , A61F2/46 , A61F2/82 , A61L27/18 , A61L29/04 , A61L29/06 , C08G18/10 , C08G18/48 , C08G18/69
CPC分类号: C08G18/4854 , A61B17/17 , A61F2/30756 , A61F2/441 , A61F2/4601 , A61F2/4611 , A61L27/18 , A61L29/041 , A61L29/06 , C08G18/10 , C08G18/69 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/1671 , A61B17/1675 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/442 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/30235 , A61F2002/30583 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61L2430/38 , B01F2215/0039
摘要: A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable composition can be delivered using minimally invasive means to a tissue site and there fully cured provide a permanent and biocompatible prosthesis for repair of the tissue site. Further provided are a mold apparatus, e.g., in the form of a balloon or tubular cavity, for receiving a biomaterial composition, and a method for delivering and filling the mold apparatus with a curable composition in situ to provide a prosthesis for tissue repair.
摘要翻译: 一种用于修复组织部位的方法和相关组合物和装置。 该方法包括使用可固化的聚氨酯生物材料组合物,其具有适于在使用时混合的多个部分,以提供可流动的组合物并开始固化。 可流动组合物可以使用微创手段递送到组织部位,并且完全固化提供用于修复组织部位的永久性和生物相容性假体。 还提供了一种用于接收生物材料组合物的气球或管状空腔形式的模具装置,以及用于在原位地递送和填充具有可固化组合物的模具装置以提供用于组织修复的假体的方法。
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8.
公开(公告)号:US20100145457A1
公开(公告)日:2010-06-10
申请号:US12479402
申请日:2009-06-05
申请人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
发明人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
IPC分类号: A61F2/44
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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公开(公告)号:US06306177B1
公开(公告)日:2001-10-23
申请号:US08993468
申请日:1997-12-18
IPC分类号: A61F230
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable composition can be delivered using minimally invasive means to a tissue site and there fully cured provide a permanent and biocompatible prosthesis for repair of the tissue site. Further provided are a mold apparatus, e.g., in the form of a balloon or tubular cavity, for receiving a biomaterial composition, and a method for delivering and filling the mold apparatus with a curable composition in situ to provide a prosthesis for tissue repair.
摘要翻译: 一种用于修复组织部位的方法和相关组合物和装置。 该方法包括使用可固化的聚氨酯生物材料组合物,其具有适于在使用时混合的多个部分,以提供可流动的组合物并开始固化。 可流动组合物可以使用微创手段递送到组织部位,并且完全固化提供用于修复组织部位的永久性和生物相容性假体。 还提供了一种用于接收生物材料组合物的气球或管状空腔形式的模具装置,以及用于在原位地递送和填充具有可固化组合物的模具装置以提供用于组织修复的假体的方法。
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公开(公告)号:US07914582B2
公开(公告)日:2011-03-29
申请号:US11953203
申请日:2007-12-10
申请人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
发明人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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