公开(公告)号：US08143441B2

公开(公告)日：2012-03-27

申请号：US11447236

申请日：2006-06-05

申请人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Anthony Woods ,  Peter E. Rogers

发明人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Anthony Woods ,  Peter E. Rogers

IPC分类号： C07F9/38 ,  B01J37/18

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J23/40 ,  C07F9/3813 ,  Y02P20/582

摘要： This invention relates to an improved catalyst, comprising a carbon support having a noble metal at its surface, for use in catalyzing liquid phase oxidation reactions, especially in an acidic oxidative environment and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; a process for the preparation of the improved catalyst; a liquid phase oxidation process using such a catalyst wherein the catalyst exhibits improved resistance to noble metal leaching, particularly in acidic oxidative environments and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; and a liquid phase oxidation process in which N-(phosphonomethyl)iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., “glyphosate”) or a salt thereof using such a catalyst wherein the oxidation of the formaldehyde and formic acid by-products into carbon dioxide and water is increased.

摘要翻译： 本发明涉及一种改进的催化剂，其包括在其表面具有贵金属的碳载体，用于催化液相氧化反应，特别是在酸性氧化环境中和在溶剂存在下，反应物，中间体或溶解产物 贵金属; 改进的催化剂的制备方法; 使用这种催化剂的液相氧化方法，其中催化剂表现出改善的贵金属浸出耐受性，特别是在酸性氧化环境和溶剂存在下，反应物，中间体或增溶贵金属的产物; 和其中N-（膦酰基甲基）亚氨基二乙酸（即“PMIDA”）或其盐被氧化以形成N-（膦酰基甲基）甘氨酸（即“草甘膦”）或其盐的液相氧化方法， 催化剂，其中甲醛和甲酸副产物氧化成二氧化碳和水增加。

公开(公告)号：US06603039B1

公开(公告)日：2003-08-05

申请号：US09408296

申请日：1999-09-29

申请人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

发明人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

IPC分类号： C07F938

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J23/40 ,  C07F9/3813 ,  Y02P20/582

摘要： This invention relates to an improved catalyst, comprising a carbon support having a noble metal at its surface, for use in catalyzing liquid phase oxidation reactions, especially in an acidic oxidative environment and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; a process for the preparation of the improved catalyst; a liquid phase oxidation process using such a catalyst wherein the catalyst exhibits improved resistance to noble metal leaching, particularly in acidic oxidative environments and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; and a liquid phase oxidation process in which N-(phosphonomethyl)iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., “glyphosate”) or a salt thereof using such a catalyst wherein the oxidation of the formaldehyde and formic acid by-products into carbon dioxide and water is increased.

公开(公告)号：US06337298B1

公开(公告)日：2002-01-08

申请号：US09248655

申请日：1999-02-11

申请人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

发明人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

IPC分类号： B01J2118

摘要： This invention relates to an improved catalyst, comprising a carbon support having a noble metal at its surface, for use in catalyzing liquid phase oxidation reactions, especially in an acidic oxidative environment and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; a process for the preparation of the improved catalyst; a liquid phase oxidation process using such a catalyst wherein the catalyst exhibits improved resistance to noble metal leaching, particularly in acidic oxidative environments and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; and a liquid phase oxidation process in which N-(phosphonomethyl)iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., “glyphosate”) or a salt thereof using such a catalyst wherein the oxidation of the formaldehyde and formic acid by-products into carbon dioxide and water is increased.

公开(公告)号：US07067693B1

公开(公告)日：2006-06-27

申请号：US09408323

申请日：1999-09-29

申请人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Anthony Woods ,  Peter E. Rogers ,  Jingye Liu ,  William A. Scholle

发明人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Anthony Woods ,  Peter E. Rogers ,  Jingye Liu ,  William A. Scholle

IPC分类号： C07F9/28 ,  B01J21/18

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J23/40 ,  C07F9/3813 ,  Y02P20/582

摘要： This invention relates to an improved catalyst, comprising a carbon support having a noble metal at its surface, for use in catalyzing liquid phase oxidation reactions, especially in an acidic oxidative environment and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; a process for the preparation of the improved catalyst; a liquid phase oxidation process using such a catalyst wherein the catalyst exhibits improved resistance to noble metal leaching, particularly in acidic oxidative environments and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; and a liquid phase oxidation process in which N-(phosphonomethyl)iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl) glycine (i.e., “glyphosate”) or a salt thereof using such a catalyst wherein the oxidation of the formaldehyde and formic acid by-products into carbon dioxide and water is increased.

摘要翻译： 本发明涉及一种改进的催化剂，其包括在其表面具有贵金属的碳载体，用于催化液相氧化反应，特别是在酸性氧化环境中和在溶剂存在下，反应物，中间体或溶解产物 贵金属; 改进的催化剂的制备方法; 使用这种催化剂的液相氧化方法，其中催化剂表现出改善的贵金属浸出耐受性，特别是在酸性氧化环境和溶剂存在下，反应物，中间体或增溶贵金属的产物; 和其中N-（膦酰基甲基）亚氨基二乙酸（即“PMIDA”）或其盐被氧化以形成N-（膦酰基甲基）甘氨酸（即“草甘膦”）或其盐的液相氧化方法， 催化剂，其中甲醛和甲酸副产物氧化成二氧化碳和水增加。

公开(公告)号：US06417133B1

公开(公告)日：2002-07-09

申请号：US09248655

申请日：1999-02-11

申请人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

发明人： Jerry R. Ebner ,  Mark A. Leiber ,  Kam-To Wan ,  Peter E. Rogers ,  Jingyue Liu ,  Anthony Woods

IPC分类号： B01J2118

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J23/40 ,  C07F9/3813 ,  Y02P20/582

摘要： This invention relates to an improved catalyst, comprising a carbon support having a noble metal at its surface, for use in catalyzing liquid phase oxidation reactions, especially in an acidic oxidative environment and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; a process for the preparation of the improved catalyst; a liquid phase oxidation process using such a catalyst wherein the catalyst exhibits improved resistance to noble metal leaching, particularly in acidic oxidative environments and in the presence of solvents, reactants, intermediates, or products which solubilize noble metals; and a liquid phase oxidation process in which N-(phosphonomethyl)iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., “glyphosate”) or a salt thereof using such a catalyst wherein the oxidation of the formaldehyde and formic acid by-products into carbon dioxide and water is increased.

摘要翻译： 本发明涉及一种改进的催化剂，其包括在其表面具有贵金属的碳载体，用于催化液相氧化反应，特别是在酸性氧化环境中和在溶剂存在下，反应物，中间体或溶解产物 贵金属; 改进的催化剂的制备方法; 使用这种催化剂的液相氧化方法，其中催化剂表现出改善的贵金属浸出耐受性，特别是在酸性氧化环境和溶剂存在下，反应物，中间体或增溶贵金属的产物; 和其中N-（膦酰基甲基）亚氨基二乙酸（即“PMIDA”）或其盐被氧化以形成N-（膦酰基甲基）甘氨酸（即“草甘膦”）或其盐的液相氧化方法， 催化剂，其中甲醛和甲酸副产物氧化成二氧化碳和水增加。

公开(公告)号：US06586621B2

公开(公告)日：2003-07-01

申请号：US09746186

申请日：2000-12-21

申请人： Mark A. Leiber ,  Jerry R. Ebner ,  Kam-To Wan ,  Anthony Woods ,  Peter Rogers

发明人： Mark A. Leiber ,  Jerry R. Ebner ,  Kam-To Wan ,  Anthony Woods ,  Peter Rogers

IPC分类号： C07F922

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J37/0205 ,  C07F9/3813

摘要： This invention relates to the use of a supplemental promoter in conjunction with a noble-metal-containing catalyst comprising a carbon support in catalyzing liquid phase oxidation reactions, a process for making of an improved catalyst comprising such a supplemental promoter, and an improved catalyst comprising such a supplemental promoter. In a particularly preferred embodiment, a supplemental promoter (most preferably bismuth or tellurium) is used in conjunction with a noble-metal-containing catalyst comprising a carbon support in a liquid phase oxidation process wherein N-(phosphonomethyl) iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl) glycine (i.e., “glyphosate”) or a salt thereof. The benefits of such a process include increased oxidation of the formaldehyde and formic acid by-products, and, consequently, decreased final concentrations of those by-products as well as other undesirable by-products, most notably N-methyl-N-(phosphonomethyl) glycine (i.e., “NMG”).

摘要翻译： 本发明涉及补充促进剂与包含碳载体催化液相氧化反应的含贵金属的催化剂的使用，制备包含这种补充促进剂的改进的催化剂的方法，以及改进的催化剂，包括 在一个特别优选的实施方案中，补充促进剂（最优选铋或碲）与液相氧化方法中含有碳载体的含贵金属的催化剂结合使用，其中N-（膦酰基甲基）亚氨基二乙酸 酸（即“PMIDA”）或其盐被氧化形成N-（膦酰基甲基）甘氨酸（即“草甘膦”）或其盐。 这种方法的好处包括增加甲醛和甲酸副产物的氧化，从而减少那些副产物以及其它不希望的副产物的最终浓度，特别是N-甲基-N-（膦酰甲基 ）甘氨酸（即“NMG”）。

公开(公告)号：US06963009B2

公开(公告)日：2005-11-08

申请号：US10427830

申请日：2003-05-01

申请人： Mark A. Leiber ,  Jerry R. Ebner ,  Kam-To Wan ,  Anthony Woods ,  Peter Rogers

发明人： Mark A. Leiber ,  Jerry R. Ebner ,  Kam-To Wan ,  Anthony Woods ,  Peter Rogers

IPC分类号： A01N57/20 ,  B01J21/18 ,  B01J23/56 ,  B01J37/02 ,  C07B61/00 ,  C07F9/38 ,  C07F9/28 ,  C07C53/02

CPC分类号： B01J23/56 ,  B01J21/18 ,  B01J37/0205 ,  C07F9/3813

摘要： This invention relates to the use of a supplemental promoter in conjunction with a noble-metal-containing catalyst comprising a carbon support in catalyzing liquid phase oxidation reactions.In a particularly preferred embodiment, a supplemental promoter (most preferably bismuth or tellurium) is used in conjunction with a noble-metal-containing catalyst comprising a carbon support in a liquid phase oxidation process wherein N-(phosphonomethyl) iminodiacetic acid (i.e., “PMIDA”) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., “glyphosate”) or a salt thereof. The benefits of such a process include oxidation of the formaldehyde and formic acid by-products, and, consequently, decreased final concentrations of those by-products as well as other undesirable by-products, most notably N-methyl-N-(phosphonomethyl)glycine (i.e., “NMG”).

摘要翻译： 本发明涉及补充促进剂与含有碳载体催化液相氧化反应的含贵金属催化剂的联合使用。 在特别优选的实施方案中，补充促进剂（最优选铋或碲）与液相氧化方法中含有碳载体的含贵金属的催化剂结合使用，其中N-（膦酰基甲基）亚氨基二乙酸（即“ PMIDA“）或其盐被氧化形成N-（膦酰基甲基）甘氨酸（即”草甘膦“）或其盐。 这种方法的益处包括甲醛和甲酸副产物的氧化，从而减少了副产物以及其它不希望的副产物的最终浓度，最值得注意的是N-甲基-N-（膦酰基甲基） 甘氨酸（即“NMG”）。

公开(公告)号：US07164049B2

公开(公告)日：2007-01-16

申请号：US10400558

申请日：2003-03-27

申请人： Jerry R. Ebner ,  Zhi Guo ,  Arnold Hershman ,  Loraine M. Klein ,  William D. McGhee ,  Mark Paster ,  Indra Prakash

发明人： Jerry R. Ebner ,  Zhi Guo ,  Arnold Hershman ,  Loraine M. Klein ,  William D. McGhee ,  Mark Paster ,  Indra Prakash

IPC分类号： C07C27/00

CPC分类号： C07C303/24 ,  C07C17/275 ,  C07C29/095 ,  C07C29/12 ,  C07C29/124 ,  C07C29/132 ,  C07C29/147 ,  C07C29/149 ,  C07C45/002 ,  C07C45/38 ,  C07C47/02 ,  C07K5/06113 ,  Y02P20/127 ,  C07C19/01 ,  C07C305/08 ,  C07C31/125

摘要： 3,3-Dimethylbutanal is prepared from 3,3-dimethylbutanol. Intermediate 3,3-dimethylbutanol is obtained by reacting ethylene, isopropylene and a mineral acid to produce a 3,3-dimethylbutyl ester which is hydrolyzed to the alcohol. The hydrolysis step is effectively carried out by reactive distillation. Alternatively, 3,3-dimethylbutanal is prepared from 3,3-dimethylbutanol obtained by reduction of the corresponding carboxylic acid or 1,2-epoxy-3,3-dimethylbutane, or by hydrolysis of 1-halo-3,3-dimethylbutane. Fixed bed gas phase and stirred tank liquid phase processes are provided for converting 3,3-dimethylbutanol to 3,3-dimethylbutanal by catalytic dehydrogenation.

摘要翻译： 3,3-二甲基丁醛由3,3-二甲基丁醇制备。 中间体3,3-二甲基丁醇通过使乙烯，异丙烯和无机酸反应得到3,3-二甲基丁酯，将其水解成醇。 水解步骤通过反应蒸馏有效地进行。 或者，通过还原相应的羧酸或1,2-环氧-3,3-二甲基丁烷或通过1-卤代-3,3-二甲基丁烷的水解得到的3,3-二甲基丁醇制备3,3-二甲基丁醛。 提供固定床气相和搅拌釜液相方法，通过催化脱氢将3,3-二甲基丁醇转化为3,3-二甲基丁醛。

公开(公告)号：US5275996A

公开(公告)日：1994-01-04

申请号：US887254

申请日：1992-05-22

申请人： William J. Andrews ,  Jerry R. Ebner ,  Timothy R. Felthouse

发明人： William J. Andrews ,  Jerry R. Ebner ,  Timothy R. Felthouse

IPC分类号： C07D307/60 ,  B01J27/198 ,  B01J35/10 ,  B01J37/00 ,  C07B61/00 ,  C07C51/215

CPC分类号： C07C51/215 ,  B01J23/002 ,  B01J27/198 ,  B01J35/0026 ,  B01J35/1014 ,  B01J35/1038 ,  B01J35/108 ,  B01J37/0018 ,  B01J2523/00

摘要： An activated porous phosphorus/vanadium oxide catalyst adapted for the catalytic oxidation of a hydrocarbon to produce a carboxylic acid anhydride. The catalyst comprises shaped bodies having a B.E.T. surface area of at least about 15 m.sup.2 /g, an average vanadium oxidation state of between about 4.0 and about 4.5, a total pore volume of at least about 0.15 cc/g, a normalized apparent shaped body density of between about 1.25 and about 2.0 g/cc, and a crush strength of at least about 4 pounds. At least about 5% of the pore volume of the catalyst is constituted of pores having a diameter of at least about 0.8 microns, and at least about 4% of the pore volume is constituted of pores having a diameter of at least about 10 microns. The catalyst is prepared by mixing a particulate phosphorus/vanadium oxide precursor with a pore modification agent to produce a modified catalyst precursor composition, forming the modified precursor composition into a predetermined shape, and removing the pore modification agent substantially at a temperature below 300.degree. C.

摘要翻译： 一种活化的多孔磷/氧化钒催化剂，适于催化氧化烃以产生羧酸酐。 催化剂包括具有B.E.T.的成形体。 表面积为至少约15m 2 / g，平均钒氧化态为约4.0至约4.5，总孔体积为至少约0.15cc / g，归一化表观体密度为约1.25至约2.0 g / cc，压碎强度至少约4磅。 催化剂的孔体积的至少约5％由直径为至少约0.8微米的孔构成，孔体积的至少约4％由直径至少为约10微米的孔构成。 通过将颗粒状磷/钒氧化物前体与孔改性剂混合以制备改性催化剂前体组合物，将改性前体组合物形成预定形状并且基本上在低于300℃的温度下除去孔改性剂来制备催化剂 。

公开(公告)号：US4626412A

公开(公告)日：1986-12-02

申请号：US682028

申请日：1984-12-14

申请人： Jerry R. Ebner ,  John T. Gleaves

发明人： Jerry R. Ebner ,  John T. Gleaves

IPC分类号： B01J3/00 ,  B01J3/02 ,  B01J3/03 ,  B01J8/00 ,  B01J8/02 ,  B01J8/06 ,  G01N31/10

CPC分类号： B01J3/006 ,  B01J3/02 ,  B01J3/03 ,  B01J8/001 ,  B01J8/0278 ,  B01J8/067 ,  G01N31/10 ,  B01J2208/00061 ,  B01J2208/0007 ,  B01J2208/00132 ,  B01J2208/00176 ,  B01J2208/00212 ,  B01J2208/00345 ,  B01J2208/00407 ,  B01J2208/00415

摘要： Disclosed are an apparatus and a method for carrying out and studying catalysis and catalyzed chemical reactions. Disclosed is a reactor with a catalyst zone, under vacuum, into which a very rapid pulse of reactant gas is pulsed. The products are analyzed by a real-time method of analysis, such as mass spectrometry. The apparatus and method can detect reaction intermediates and products, and can indicate their sequence of production.

摘要翻译： 公开了一种用于进行和研究催化和催化化学反应的装置和方法。 公开了一种在真空下具有催化剂区域的反应器，其中脉冲非常快的反应气体脉冲。 通过实时分析方法（如质谱法）对产物进行分析。 该装置和方法可以检测反应中间体和产物，并可以指示其生产顺序。