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    Retrograde pressure regulated infusion
    1.
    发明授权
    Retrograde pressure regulated infusion 有权
    逆行压力调节输液

    公开(公告)号：US08182463B2

    公开(公告)日：2012-05-22

    申请号：US11609143

    申请日：2006-12-11

    申请人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    发明人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    IPC分类号： A61M31/00

    CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

    摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.

    摘要翻译： 输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉 截面面积至少约5 mm2; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或 合成胶乳 其中所述气囊适于膨胀至约4至约15mm的直径范围。

    Retrograde pressure regulated infusion
    2.
    发明授权
    Retrograde pressure regulated infusion 有权
    逆行压力调节输液

    公开(公告)号：US07250041B2

    公开(公告)日：2007-07-31

    申请号：US10387048

    申请日：2003-03-12

    申请人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    发明人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    IPC分类号： A61M25/00

    CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

    摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.

    摘要翻译： 输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉 至少约5毫米2的截面积; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或 合成胶乳 其中所述气囊适于膨胀至约4至约15mm的直径范围。

    METHOD AND APPARATUS FOR DELIVERING COMBINED ELECTRICAL AND DRUG THERAPIES
    7.
    发明申请
    METHOD AND APPARATUS FOR DELIVERING COMBINED ELECTRICAL AND DRUG THERAPIES 有权
    用于递送组合电和药物治疗的方法和装置

    公开(公告)号：US20090259268A1

    公开(公告)日：2009-10-15

    申请号：US12491957

    申请日：2009-06-25

    申请人： Gregory Waimong Chan

    发明人： Gregory Waimong Chan

    IPC分类号： A61N1/362 ,  H01S4/00 ,  A61M31/00

    CPC分类号： A61M5/14276 ,  A61M2205/3523 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2230/04 ,  A61M2230/08 ,  A61N1/375 ,  A61N1/3962 ,  A61N1/3968 ,  Y10T29/49002

    摘要： A cardiac rhythm management (CRM) system includes an implantable medical device that delivers combined electrical and drug therapies. The implantable medical device includes a drug reservoir that is refillable after implantation. In one embodiment, the implantable medical device includes an implantable housing encapsulating a pulse generator circuit and a drug delivery device. In another embodiment, the implantable medical device includes an implantable pulse generator and an implantable drug delivery device fastened to each other.

    摘要翻译： 心律管理（CRM）系统包括可植入医疗装置，其提供组合的电疗和药物疗法。 可植入医疗装置包括在植入后可再填充的药物储存器。 在一个实施例中，可植入医疗装置包括封装脉冲发生器电路和药物输送装置的可植入壳体。 在另一个实施例中，可植入医疗装置包括可植入的脉冲发生器和彼此紧固的可植入药物输送装置。

    Needle catheter
    8.
    发明授权
    Needle catheter 有权
    针导管

    公开(公告)号：US08152758B2

    公开(公告)日：2012-04-10

    申请号：US11841470

    申请日：2007-08-20

    申请人： Gregory Waimong Chan ,  Fernando Gonzalez ,  Thuhuong Thi Phan ,  Dwight A. Ambat ,  Manolo Lumauig ,  Mina W. Chow

    发明人： Gregory Waimong Chan ,  Fernando Gonzalez ,  Thuhuong Thi Phan ,  Dwight A. Ambat ,  Manolo Lumauig ,  Mina W. Chow

    IPC分类号： A61M29/00

    CPC分类号： A61M29/00

    摘要： An apparatus including an expandable body; at least one delivery cannula coupled to an exterior portion of the expandable body; a needle having a protuberance thereon disposed in a lumen of the at least one delivery cannula; a stop disposed in the lumen of the at least one delivery cannula at a position distal to the protuberance on the needle. A method including positioning a catheter assembly including at least one needle delivery device disposed in an at least one delivery cannula, the at least one delivery cannula having an exit end; modifying the shape of the catheter assembly to modify the orientation of the exit end of the at least one delivery cannula at a region of interest; and advancing the at least one needle delivery device beyond the exit end of the at least one delivery cannula according to a controlled orientation.

    摘要翻译： 一种包括可膨胀体的装置; 至少一个输送插管，其连接到所述可膨胀体的外部部分; 其上具有突起的针，其设置在所述至少一个输送插管的内腔中; 设置在所述至少一个输送套管的内腔中的位于远离所述针头上的突起的位置处的止动件。 一种方法，包括定位包括设置在至少一个输送插管中的至少一个针递送装置的导管组件，所述至少一个输送插管具有出口端; 改变导管组件的形状以改变感兴趣区域中至少一个输送插管的出口端的取向; 以及根据受控的取向将所述至少一个针输送装置推进到所述至少一个输送插管的出口端。

    Method and apparatus for delivering combined electrical and drug therapies
    9.
    发明授权
    Method and apparatus for delivering combined electrical and drug therapies 失效
    用于递送组合电疗和药物疗法的方法和装置

    公开(公告)号：US07567841B2

    公开(公告)日：2009-07-28

    申请号：US10922650

    申请日：2004-08-20

    申请人： Gregory Waimong Chan

    发明人： Gregory Waimong Chan

    IPC分类号： A61N1/36

    CPC分类号： A61M5/14276 ,  A61M2205/3523 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2230/04 ,  A61M2230/08 ,  A61N1/375 ,  A61N1/3962 ,  A61N1/3968 ,  Y10T29/49002

    摘要： A cardiac rhythm management (CRM) system includes an implantable medical device that delivers combined electrical and drug therapies. The implantable medical device includes a drug reservoir that is refillable after implantation. In one embodiment, the implantable medical device includes an implantable housing encapsulating a pulse generator circuit and a drug delivery device. In another embodiment, the implantable medical device includes an implantable pulse generator and an implantable drug delivery device fastened to each other.

    摘要翻译： 心律管理（CRM）系统包括可植入医疗装置，其提供组合的电疗法和药物疗法。 可植入医疗装置包括在植入后可再填充的药物储存器。 在一个实施例中，可植入医疗装置包括封装脉冲发生器电路和药物输送装置的可植入壳体。 在另一个实施例中，可植入医疗装置包括可植入的脉冲发生器和彼此紧固的可植入药物输送装置。

    Modified needle catheter for directional orientation delivery
    10.
    发明授权
    Modified needle catheter for directional orientation delivery 有权
    用于定向定向输送的改进的针导管

    公开(公告)号：US07273469B1

    公开(公告)日：2007-09-25

    申请号：US10749354

    申请日：2003-12-31

    申请人： Gregory Waimong Chan ,  Fernando Gonzalez ,  Thuhuong Thi Phan ,  Dwight A. Ambat ,  Manolo Lumauig ,  Mina W. Chow

    发明人： Gregory Waimong Chan ,  Fernando Gonzalez ,  Thuhuong Thi Phan ,  Dwight A. Ambat ,  Manolo Lumauig ,  Mina W. Chow

    IPC分类号： A61M29/00

    CPC分类号： A61M29/00

    摘要： Methods and apparatus for delivering a treatment agent through a percutaneous delivery apparatus are herein disclosed. In some embodiments, an apparatus can include an expandable body with at least one delivery cannula having a lumen therethrough coupled to an exterior portion of the expandable body. The expandable body can be coupled to a delivery assembly with a hub. The delivery cannula can house at least one needle with a protuberance on a distal end. A portion of the hub can house at least one needle with a protuberance on a proximal end. In some embodiments, the protuberance (proximal or distal) can direct the orientation of the needle during an application of treatment agent. In some embodiments, the delivery cannula can include at least one stop for controlling the movement of the needle during an application of treatment agent. In some embodiments, a sheath can be disposed around the delivery cannula.

    摘要翻译： 本文公开了通过经皮输送装置输送治疗剂的方法和装置。 在一些实施例中，装置可以包括具有至少一个输送套管的可膨胀体，所述输送套管具有通过其连接到可扩张体的外部部分的内腔。 可膨胀体可以与轮毂联接到输送组件。 输送插管可以容纳至少一个具有在远端上的突起的针。 轮毂的一部分可容纳至少一根具有在近端上的突起的针。 在一些实施例中，在施用治疗剂期间，突起（近端或远端）可引导针的取向。 在一些实施例中，输送套管可以包括至少一个止挡件，用于在施用治疗剂期间控制针头的移动。 在一些实施例中，护套可以设置在输送套管周围。