摘要:
The present invention provides compounds of the Formula I and II: wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, and methods and intermediates for their preparation and uses thereof.
摘要:
Compounds having the formula (I), are useful as p38 kinase inhibitors, wherein R4 and R5 are hydrogen, halogen, cyano, haloalkyl, or haloalkoxy, but are not both hydrogen; R6 and R7 are optional substituents, and Q is a non-aromatic moiety as defined in the specification.
摘要翻译:具有式(I)的化合物可用作p38激酶抑制剂,其中R 4和R 5是氢,卤素,氰基,卤代烷基或卤代烷氧基,但不是 氢; R 6和R 7是任选的取代基,Q是说明书中定义的非芳族部分。
摘要:
The present invention discloses compounds corresponding to formula wherein A, R, X, Y, R, R1 and R2 are as defined above, pharmaceutical formulations, methods of making and uses thereof.
摘要:
The present invention discloses compounds corresponding to formula wherein A, R, X, Y, R, R1 and R2 are as defined above, pharmaceutical formulations, methods of making and uses thereof.
摘要:
The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
摘要:
The invention is concerned with novel pyrrolidine-3,4-dicarboxamide derivatives of formula (I) wherein R1 to R9 and X are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments
摘要:
Image data of optically acquired input images (1) are processed for emphasizing at least two object classes. Each pixel is subjected to a rough classification (10) based on first criteria that determine whether or not a pixel is relevant for an object recognition. A reduced image (11) is formed from the relevant pixels and irrelevant pixels are omitted. The reduced image (11) is filtered (20) for forming at least two correlated filtered images (21, 22, 23) based on second criteria. Classified images (31A, 32A, 33A) are formed from the filtered images by classifiers that work in accordance with predetermined rules. Weighting factors are allocated to each object class. The classified images are merged in accordance with an algorithm to make a combined global evaluation for each object class. The global evaluation decides, based on the merged images (41A, 41B, 41C), for each pixel whether the respective pixel belongs to an object class and if so to which object class.
摘要:
A method for effecting the airborne determination of geographic coordinates of corresponding pixels from digital synthetic aperture radar images, where the SAR images are available in the form of slant range images and the recording position of the respective SAR image is known. The coordinates of the corresponding pixels in the SAR images and the corresponding range gates are used in each case to determine the distance between a corresponding resolution cell on the ground and the respective recording position of the respective SAR image. The determined distances and associated recording positions of the SAR images are used to determine the geographic coordinates of the corresponding pixels in the SAR images by employing a WGS84 ellipsoid.
摘要:
A method for effecting the airborne determination of geographic coordinates of corresponding pixels from digital synthetic aperture radar images, where the SAR images are available in the form of slant range images and the recording position of the respective SAR image is known. The coordinates of the corresponding pixels in the SAR images and the corresponding range gates are used in each case to determine the distance between a corresponding resolution cell on the ground and the respective recording position of the respective SAR image. The determined distances and associated recording positions of the SAR images are used to determine the geographic coordinates of the corresponding pixels in the SAR images by employing a WGS84 ellipsoid.
摘要:
The invention is concerned with novel 4-aminomethyl benzamidine derivatives of formula (I) wherein Ar and X are as defined in the description and in the claims, as well as prodrugs and pharmaceutically acceptable salts thereof These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.