公开(公告)号：USH2021H1

公开(公告)日：2002-05-07

申请号：US09377465

申请日：1999-08-19

申请人： JoAnn Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Genshi Zhao ,  Pamela Kay Rockey

发明人： JoAnn Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Genshi Zhao ,  Pamela Kay Rockey

IPC分类号： G01N33554

摘要： The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.

公开(公告)号：USH2070H1

公开(公告)日：2003-07-01

申请号：US08987119

申请日：1997-12-08

申请人： Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Timothy Ivan Meier ,  Pamela Kay Rockey ,  Genshi Zhao

发明人： Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Timothy Ivan Meier ,  Pamela Kay Rockey ,  Genshi Zhao

IPC分类号： C12N1531

摘要： The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

公开(公告)号：USH2023H1

公开(公告)日：2002-05-07

申请号：US08986967

申请日：1997-12-08

申请人： Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Pamela Kay Rockey ,  Patti Jean Treadway

发明人： Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Pamela Kay Rockey ,  Patti Jean Treadway

IPC分类号： C07K14315

摘要： The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

公开(公告)号：US6162617A

公开(公告)日：2000-12-19

申请号：US987151

申请日：1997-12-08

申请人： Stanley Gene Burgett ,  Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Robert Brown Peery ,  Paul Robert Rosteck, Jr. ,  Genshi Zhao

发明人： Stanley Gene Burgett ,  Jo Ann Hoskins ,  Stanley Richard Jaskunas, Jr. ,  Robert Brown Peery ,  Paul Robert Rosteck, Jr. ,  Genshi Zhao

IPC分类号： C07K14/315 ,  C12N1/21 ,  C12N9/12 ,  C12N9/24 ,  C12N15/10 ,  C12N15/31 ,  C12N15/74 ,  C12P21/04 ,  G01N33/569 ,  C12P21/06 ,  C12N1/00 ,  C12N1/12

CPC分类号： G01N33/56944 ,  C07K14/3156 ,  C12N9/1247 ,  C12N15/1006 ,  C12N15/746 ,  C12Y302/01018 ,  G01N2333/315 ,  Y10S435/822

摘要： The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.

摘要翻译： 本发明提供编码肺炎链球菌dnaG的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。