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公开(公告)号：US20100286209A1
公开(公告)日：2010-11-11
申请号：US12773186
申请日：2010-05-04
申请人： Daohong Chen , Hong-Yu Li , Genshi Zhao
发明人： Daohong Chen , Hong-Yu Li , Genshi Zhao
IPC分类号： A61K31/4439 , C07D401/14 , A61P35/00
CPC分类号： C07D401/14 , A61K31/4439
摘要： The present invention provides vinyl indazolyl compounds useful in the treatment of cancer.
摘要翻译： 本发明提供了可用于治疗癌症的乙烯基吲唑基化合物。
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公开(公告)号：USH2021H1
公开(公告)日：2002-05-07
申请号：US09377465
申请日：1999-08-19
IPC分类号： G01N33554
摘要： The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.
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公开(公告)号：USH2085H1
公开(公告)日：2003-10-07
申请号：US09014897
申请日：1998-01-28
申请人： Jo Ann Hoskins , S. Richard Jaskunas, Jr. , Genshi Zhao , Pamela K. Rockey , Paul R. Rosteck, Jr. , Franklin H. Norris
发明人： Jo Ann Hoskins , S. Richard Jaskunas, Jr. , Genshi Zhao , Pamela K. Rockey , Paul R. Rosteck, Jr. , Franklin H. Norris
IPC分类号： C12N1509
摘要： The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.
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公开(公告)号：US6071724A
公开(公告)日：2000-06-06
申请号：US986765
申请日：1997-12-08
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding Era of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌时代的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：US08268869B2
公开(公告)日：2012-09-18
申请号：US12773186
申请日：2010-05-04
申请人： Daohong Chen , Hong-Yu Li , Genshi Zhao
发明人： Daohong Chen , Hong-Yu Li , Genshi Zhao
IPC分类号： C07D401/14 , A61K31/4439
CPC分类号： C07D401/14 , A61K31/4439
摘要： The present invention provides vinyl indazolyl compounds useful in the treatment of cancer.
摘要翻译： 本发明提供了可用于治疗癌症的乙烯基吲唑基化合物。
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公开(公告)号：USH2070H1
公开(公告)日：2003-07-01
申请号：US08987119
申请日：1997-12-08
申请人： Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Timothy Ivan Meier , Pamela Kay Rockey , Genshi Zhao
发明人： Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Timothy Ivan Meier , Pamela Kay Rockey , Genshi Zhao
IPC分类号： C12N1531
摘要： The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
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公开(公告)号：US6060282A
公开(公告)日：2000-05-09
申请号：US987144
申请日：1997-12-08
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding dpj of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌dpj的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：US6162617A
公开(公告)日：2000-12-19
申请号：US987151
申请日：1997-12-08
申请人： Stanley Gene Burgett , Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Robert Brown Peery , Paul Robert Rosteck, Jr. , Genshi Zhao
发明人： Stanley Gene Burgett , Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Robert Brown Peery , Paul Robert Rosteck, Jr. , Genshi Zhao
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06 , C12N1/00 , C12N1/12
CPC分类号： G01N33/56944 , C07K14/3156 , C12N9/1247 , C12N15/1006 , C12N15/746 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌dnaG的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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