-
公开(公告)号:USH2023H1
公开(公告)日:2002-05-07
申请号:US08986967
申请日:1997-12-08
IPC分类号: C07K14315
摘要: The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
-
公开(公告)号:USH2070H1
公开(公告)日:2003-07-01
申请号:US08987119
申请日:1997-12-08
申请人: Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Timothy Ivan Meier , Pamela Kay Rockey , Genshi Zhao
发明人: Jo Ann Hoskins , Stanley Richard Jaskunas, Jr. , Timothy Ivan Meier , Pamela Kay Rockey , Genshi Zhao
IPC分类号: C12N1531
摘要: The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
-
公开(公告)号:US5948645A
公开(公告)日:1999-09-07
申请号:US759907
申请日:1996-12-04
申请人: Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
发明人: Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
CPC分类号: C12Q1/533 , C12N9/90 , Y10S530/82 , Y10S530/825
摘要: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
摘要翻译: 本发明提供编码肺炎链球菌的干肽生物合成基因murI的分离的核酸化合物。 还提供了用于表达MurI酶产物的载体和转化的异源宿主细胞,以及用于鉴定抑制干肽生物合成的化合物的方法。
-
公开(公告)号:US06171834B2
公开(公告)日:2001-01-09
申请号:US09303272
申请日:1999-04-30
申请人: Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
发明人: Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
IPC分类号: C12N900
CPC分类号: C12Q1/533 , C12N9/90 , Y10S530/82 , Y10S530/825
摘要: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
摘要翻译: 本发明提供编码肺炎链球菌的干肽生物合成基因murI的分离的核酸化合物。 还提供了用于表达MurI酶产物的载体和转化的异源宿主细胞,以及用于鉴定抑制干肽生物合成的化合物的方法。
-
公开(公告)号:USH2021H1
公开(公告)日:2002-05-07
申请号:US09377465
申请日:1999-08-19
IPC分类号: G01N33554
摘要: The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.
-
公开(公告)号:US06350866B1
公开(公告)日:2002-02-26
申请号:US08987146
申请日:1997-12-08
申请人: Paul Luther Skatrud , Robert Brown Peery , Q May Wang , Paul Robert Rosteck, Jr. , Pamela Kay Rockey
发明人: Paul Luther Skatrud , Robert Brown Peery , Q May Wang , Paul Robert Rosteck, Jr. , Pamela Kay Rockey
IPC分类号: C07H2104
CPC分类号: G01N33/56944 , C07K14/3156 , C12N9/1247 , C12N15/1006 , C12N15/746 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要: The invention provides isolated nucleic acid compounds encoding FtsZ of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译: 本发明提供编码肺炎链球菌FtsZ的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞,以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
-
-
-
-
-