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公开(公告)号：US09034635B2
公开(公告)日：2015-05-19
申请号：US12918594
申请日：2009-02-19
CPC分类号： B01L7/52 , B01L3/505 , B01L2300/043 , B01L2300/0627 , B01L2300/0838 , B01L2300/18 , B01L2300/1822 , B01L2300/1844
摘要： A thermocycler apparatus and method for rapidly performing the PCR process employs at least two thermoelectric modules which are in substantial spatial opposition with an interior space present between opposing modules. One or multiple sample vessels are placed in between the modules such that the vessels are subjected to temperature cycling by the modules. The sample vessels have a minimal internal dimension that is substantially perpendicular to the modules that facilitates rapid temperature cycling. In embodiments of the invention the sample vessels may be deformable between: a) a shape having a wide mouth to facilitate filling and removing of sample fluids from the vessel, and b) a shape which is thinner for conforming to the sample cavity or interior space between the thermoelectric modules of the thermocycler for more rapid heat transfer.
摘要翻译： 用于快速执行PCR过程的热循环仪装置和方法采用至少两个热电模块，其与存在于相对模块之间的内部空间实质上空间相对。 将一个或多个样品容器放置在模块之间，使得容器经过模块的温度循环。 样品容器具有基本垂直于促进快速温度循环的模块的最小内部尺寸。 在本发明的实施例中，样品容器可以在以下之间变形：a）具有宽口的形状，以便于从容器中填充和除去样品流体，以及b）更薄的形状，以符合样品腔或内部空间 在热循环器的热电模块之间用于更快速的热传递。
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公开(公告)号：US20100291536A1
公开(公告)日：2010-11-18
申请号：US12780345
申请日：2010-05-14
CPC分类号： A61B10/0096 , A61B10/0051 , A61B90/98 , B01L3/505 , B01L2200/0689 , B01L2300/021 , B01L2300/0864 , G01N2001/005
摘要： The present invention provides a method and device for collecting treating and analysis of biological or chemical material by introducing a source material into a specimen container, transferring the source material to a processing device and thermally, chemically and/or mechanically treating the source material to alter at least one constitutive characteristic of the source material and to release or create a target material from the source material.
摘要翻译： 本发明提供了一种通过将源材料引入到样本容器中来收集生物或化学材料的处理和分析的方法和装置，将源材料转移到处理装置，并且热，化学和/或机械地处理源材料以改变 源材料的至少一个构成特征并且从源材料释放或产生靶材料。
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公开(公告)号：US20110039305A1
公开(公告)日：2011-02-17
申请号：US12918594
申请日：2009-02-19
CPC分类号： B01L7/52 , B01L3/505 , B01L2300/043 , B01L2300/0627 , B01L2300/0838 , B01L2300/18 , B01L2300/1822 , B01L2300/1844
摘要： A thermocycler apparatus and method for rapidly performing the PCR process employs at least two thermoelectric modules which are in substantial spatial opposition with an interior space present between opposing modules. One or multiple sample vessels are placed in between the modules such that the vessels are subjected to temperature cycling by the modules. The sample vessels have a minimal internal dimension that is substantially perpendicular to the modules that facilitates rapid temperature cycling. In embodiments of the invention the sample vessels may be deformable between: a) a shape having a wide mouth to facilitate filling and removing of sample fluids from the vessel, and b) a shape which is thinner for conforming to the sample cavity or interior space between the thermoelectric modules of the thermocycler for more rapid heat transfer.
摘要翻译： 用于快速执行PCR过程的热循环仪装置和方法采用至少两个热电模块，其与存在于相对模块之间的内部空间实质上空间相对。 将一个或多个样品容器放置在模块之间，使得容器经过模块的温度循环。 样品容器具有基本垂直于促进快速温度循环的模块的最小内部尺寸。 在本发明的实施例中，样品容器可以在以下之间变形：a）具有宽口的形状，以便于从容器中填充和除去样品流体，以及b）更薄的形状，以符合样品腔或内部空间 在热循环器的热电模块之间用于更快速的热传递。
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公开(公告)号：US20100288059A1
公开(公告)日：2010-11-18
申请号：US12780508
申请日：2010-05-14
CPC分类号： A61B10/0096 , A61B10/0051 , A61B90/98 , B01L3/505 , B01L2200/0689 , B01L2300/021 , B01L2300/0864 , G01N2001/005
摘要： This invention relates to the collection and handling of biological or chemical specimens. The invention provides a device and a method for collecting and preparing patient samples, such as sputum, to be used in downstream diagnostics tests. The invention reduces the handling and exposure of healthcare workers to the sample by the use of a bag in which hermetic seals are utilized to separate sample aliquots.
摘要翻译： 本发明涉及生物或化学样品的收集和处理。 本发明提供了用于收集和制备用于下游诊断测试中的患者样品（例如痰液）的装置和方法。 本发明通过使用其中使用气密封来分离样品等分试样的袋子来减少医护人员对样品的处理和暴露。
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公开(公告)号：US06547852B2
公开(公告)日：2003-04-15
申请号：US09760508
申请日：2001-01-12
IPC分类号： B01D1508
CPC分类号： G01N30/463 , G01N30/30 , G01N30/461 , G01N30/465 , G01N2030/3023 , G01N2030/623 , G01N30/46 , G01N2030/121
摘要： A method of thermally modulating a tubular member carrying a sample substance therethrough is provided. The method includes the steps of (a) directing at least one gas stream toward a tubular member in a direction substantially transverse to the tubular member, wherein the temperature of the gas stream differs from the temperature of the tubular member; and (b) varying the gas flow rate of the at least one gas stream as a function of time to thermally modulate the tubular member. An apparatus is also provided for thermal modulation and includes: a tubular member for carrying a sample substance therethrough in a fluid medium; a gas stream source for directing a gas stream toward the tubular member in a direction substantially transverse to the tubular member; a gas stream supplied from the source with a temperature that differs from the temperature of the tubular member; and a gas stream of varying gas flow rate supplied from the gas stream source as a function of time to thermally modulate the tubular member.
摘要翻译： 提供了一种通过热调制携带样品物质的管状构件的方法。 该方法包括以下步骤：（a）在基本上横向于管状构件的方向上将至少一种气流引向管状构件，其中气流的温度与管状构件的温度不同; 和（b）根据时间的函数改变至少一种气流的气体流速，以对管状构件进行热调节。 还提供了用于热调制的装置，包括：用于在流体介质中携带样品物质通过其的管状构件; 气流源，用于沿基本横向于所述管状构件的方向将气流引向所述管状构件; 从所述源供应的气流与所述管状构件的温度不同的温度; 以及从气流源供应的不同气体流速的气流作为时间的函数来热管道管状构件。
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