公开(公告)号：USRE32338E

公开(公告)日：1987-01-27

申请号：US410749

申请日：1982-08-23

申请人： John B. Alexander ,  Michael T. Dennehey ,  Richard J. Greff ,  John M. Munsch

发明人： John B. Alexander ,  Michael T. Dennehey ,  Richard J. Greff ,  John M. Munsch

IPC分类号： A61B17/122 ,  A61B17/28 ,  B25B9/02

CPC分类号： B25B9/02 ,  A61B17/122 ,  A61B17/2812

摘要： A gripper member comprises an openable and closable pair of handles interconnected by a hinge member. Each handle defines, adjacent its hinge member, an arcuate recess positioned to face the corresponding recess of the other handle and defining gripping projections therein. A wall member is positioned longitudinally on each handle to cross each arcuate recess, both wall members being positioned at the same side of their respective recesses. Accordingly, a plastic tube may be surrounded and gripped in the arcuate recesses of the handles for rotational retention thereof as a connector member is inserted into or withdrawn from the tube. At the same time, the wall members pinch the tube into closed, sealed relation with the handles in closed position.

公开(公告)号：US4227730A

公开(公告)日：1980-10-14

申请号：US43061

申请日：1979-05-29

申请人： John B. Alexander ,  T. Michael Dennehey ,  Richard J. Greff ,  John M. Munsch

发明人： John B. Alexander ,  T. Michael Dennehey ,  Richard J. Greff ,  John M. Munsch

IPC分类号： A61B17/122 ,  A61B17/28 ,  B25B9/02 ,  B25B7/02

CPC分类号： B25B9/02 ,  A61B17/122 ,  A61B17/2812

摘要： A gripper member comprises an openable and closable pair of handles interconnected by a hinge member. Each handle defines, adjacent its hinge member, an arcuate recess positioned to face the corresponding recess of the other handle and defining gripping projections therein. A wall member is positioned longitudinally on each handle to cross each arcuate recess, both wall members being positioned at the same side of their respective recesses. Accordingly, a plastic tube may be surrounded and gripped in the arcuate recesses of the handles for rotational retention thereof as a connector member is inserted into or withdrawn from the tube. At the same time, the wall members pinch the tube into closed, sealed relation with the handles in closed position.

摘要翻译： 夹持器构件包括由铰链构件互连的可打开和可关闭的一对把手。 每个手柄在其铰链构件附近限定了一个弧形凹槽，其定位成面对另一个手柄的相应凹部并且在其中限定夹紧突起。 壁构件纵向地定位在每个手柄上以横穿每个弓形凹部，两个壁构件都位于它们各自的凹部的同一侧。 因此，当连接器构件被插入或从管中取出时，塑料管可以被包围并夹在手柄的弓形凹部中以用于旋转保持。 同时，壁构件将管子夹紧到处于关闭位置的把手处于封闭的密封关系中。

公开(公告)号：US4209013A

公开(公告)日：1980-06-24

申请号：US27420

申请日：1979-04-05

申请人： John B. Alexander ,  T. Michael Dennehey ,  Richard P. Goldhaber

发明人： John B. Alexander ,  T. Michael Dennehey ,  Richard P. Goldhaber

IPC分类号： A61M1/28 ,  A61M39/16 ,  A61M39/18 ,  A61J7/00

CPC分类号： A61M39/16 ,  A61M39/18 ,  A61M1/28

摘要： A sterile connector system is provided for continuous ambulatory peritoneal dialysis in which a dialysate solution container having a transfer port is coupled to tubing extending from a patient's peritoneal cavity. The transfer port is connected to one end of a flexible housing and the patient's tubing is connected to the opposite end of the flexible housing. A sterilizing agent is introduced into the housing and in contact with the transfer port and the patient's tubing. The sterilized transfer port is thereafter connected to the sterilized patient's tubing within the housing.

摘要翻译： 提供了一种用于连续不卧床腹膜透析的无菌连接器系统，其中具有转移口的透析液溶液容器与从患者的腹膜腔延伸的管连接。 传输端口连接到柔性壳体的一端，病人的管道连接到柔性壳体的相对端。 将消毒剂引入到壳体中并与输送口和患者的管道接触。 然后将灭菌的转运口连接到外壳内的消毒的患者管。

公开(公告)号：US6121473A

公开(公告)日：2000-09-19

申请号：US26057

申请日：1998-02-19

申请人： Richard R. Schrock ,  John B. Alexander

发明人： Richard R. Schrock ,  John B. Alexander

IPC分类号： B01J31/12 ,  B01J31/18 ,  B01J31/22 ,  B01J31/34 ,  C07B61/00 ,  C07C6/04 ,  C07F7/18 ,  C07F11/00 ,  G07F11/00

CPC分类号： C07F11/00 ,  B01J31/223 ,  B01J31/2265 ,  C07F7/1892 ,  B01J2231/543 ,  B01J2531/64 ,  B01J2531/66 ,  B01J31/1805

摘要： A composition and method for the catalytic conversion of a racemic mixture of dienes to a cyclic olefin by a ring-closing metathesis (RCM) reaction are disclosed. The composition, a transition metal complex with an M.dbd.C reaction site, contains a bidentate dialkoxide of at least 80% optical purity. Because the M.dbd.C reaction site is of a sufficient shape specificity, conferred in part by the dialkoxide of sufficient rigidity and a M.dbd.N--R.sup.1 site, reacting the composition with a mixture of two enantiomcric dienes results in an olefin metathesis product that has at least a 50% enantiomeric excess of one enantiomer in the mixture. A method is also provided for reacting a composition with a racemic diene mixture to generate a metathesis product that has an enantiomeric excess of at least 50%.

摘要翻译： 公开了通过闭环复分解（RCM）反应将二烯的外消旋混合物催化转化成环状烯烃的组合物和方法。 该组合物是具有M = C反应位点的过渡金属络合物，其含有至少80％光学纯度的二齿二烷氧基化物。 因为M = C反应位点具有足够的形状特异性，部分由二烷氧基赋予足够的刚性和M = N-R1位点，使组合物与两种对映异构二烯的混合物反应，得到烯烃复分解产物，其具有 在混合物中至少50％对映异构体过量的一种对映异构体。 还提供了使组合物与外消旋二烯混合物反应以产生具有至少50％的对映异构体过量的复分解产物的方法。