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36 条记录 (耗时 0.076 秒)

    Method for heart transplant monitoring and analog telemetry calibration
    1.
    发明授权
    Method for heart transplant monitoring and analog telemetry calibration 失效
    心脏移植监测和模拟遥测校准方法

    公开(公告)号：US5782890A

    公开(公告)日：1998-07-21

    申请号：US375034

    申请日：1995-01-19

    申请人： John D. Wahlstrand ,  Peter M. J. Mulier ,  David L. Thompson

    发明人： John D. Wahlstrand ,  Peter M. J. Mulier ,  David L. Thompson

    IPC分类号： A61B5/00 ,  A61N1/37 ,  A61N1/372

    CPC分类号： A61N1/37252 ,  A61B5/413 ,  A61N1/3702 ,  A61B5/0002

    摘要： A cardiac pacemaker with an analog telemetry system. A calibration circuit within the pacemaker is adapted to provide a reference signal of known character to the pacemaker's telemetry system. The reference signal is transmitted across the telemetry link as if it were an actual cardiac signal, and received by an external programmer. Since the reference signal has known, predetermined qualities, the programmer can automatically calibrate and scale the telemetry signal from the pacemaker, thereby increasing the accuracy of the telemetry channel. The increased accuracy is particular useful in assessing rejection of a transplanted heart, which is known to be associated with a 15% decline in the peak R-wave amplitude of the cardiac signal.

    摘要翻译： 具有模拟遥测系统的心脏起搏器。 起搏器内的校准电路适于向起搏器的遥测系统提供已知特征的参考信号。 参考信号跨越遥测链路传输，就像它是一个实际的心脏信号一样，由外部编程器接收。 由于参考信号已知，预定的质量，编程器可以自动校准和缩放来自起搏器的遥测信号，从而提高遥测通道的精度。 增加的准确度对于评估移植心脏的排斥特别有用，已知其与心脏信号的峰值R波幅度下降15％相关。

    Method and apparatus for heart transplant monitoring and analog telemetry calibration
    2.
    发明授权
    Method and apparatus for heart transplant monitoring and analog telemetry calibration 失效
    用于心脏移植监测和模拟遥测校准的方法和装置

    公开(公告)号：US5402794A

    公开(公告)日：1995-04-04

    申请号：US907259

    申请日：1992-07-01

    申请人： John D. Wahlstrand ,  Peter M. J. Mulier ,  David L. Thompson

    发明人： John D. Wahlstrand ,  Peter M. J. Mulier ,  David L. Thompson

    IPC分类号： A61B5/00 ,  A61N1/372

    CPC分类号： A61N1/37211 ,  A61B5/0006 ,  A61B5/413 ,  A61N1/37252 ,  A61B5/0002

    摘要： A cardiac pacemaker with an analog telemetry system. A calibration circuit within the pacemaker is adapted to provide a reference signal of known character to the pacemaker's telemetry system. The reference signal is transmitted across the telemetry link as if it were an actual cardiac signal, and received by an external programmer. Since the reference signal has known, predetermined qualities, the programmer can automatically calibrate and scale the telemetry signal from the pacemaker, thereby increasing the accuracy of the telemetry channel. The increased accuracy is particular useful in assessing rejection of a transplanted heart, which is known to be associated with a 15% decline in the peak R-wave amplitude of the cardiac signal.

    摘要翻译： 具有模拟遥测系统的心脏起搏器。 起搏器内的校准电路适于向起搏器的遥测系统提供已知特征的参考信号。 参考信号跨越遥测链路传输，就像它是一个实际的心脏信号一样，由外部编程器接收。 由于参考信号已知，预定的质量，编程器可以自动校准和缩放来自起搏器的遥测信号，从而提高遥测通道的精度。 增加的准确度对于评估移植心脏的排斥特别有用，已知其与心脏信号的峰值R波幅度下降15％相关。

    Magnetic field sensor
    4.
    发明授权
    Magnetic field sensor 失效
    磁场传感器

    公开(公告)号：US5438990A

    公开(公告)日：1995-08-08

    申请号：US150746

    申请日：1993-11-12

    申请人： John D. Wahlstrand ,  David L. Thompson ,  Gary E. Nelson

    发明人： John D. Wahlstrand ,  David L. Thompson ,  Gary E. Nelson

    IPC分类号： A61N1/372 ,  H01L27/22 ,  A61B5/05

    CPC分类号： A61N1/37217 ,  H01L27/22

    摘要： An implantable medical device uses a solid-state sensor for detecting the application of an external magnetic field. The sensor includes first and second split-drain field-effect transistors (MAGFETs) which are cross-coupled such that an external magnetic field perpendicular to the channel regions of the MAGFETs causes an increase in current through one split-drain half of each MAGFET, and a decrease in current through the other split-drain half of each MAGFET. The sensor also includes a high-gain differential amplifier coupled between the MAGFETs for detecting changes in the current conducted through the respective split-drain halves, and produces an output voltage which changes upon application of an external magnetic field to the implantable medical device. The magnetic sensor operates at low power supply voltages and bias currents available in implantable medical devices such as a cardiac pacemaker, so that current drain and power consumption are minimized.

    摘要翻译： 可植入医疗装置使用固态传感器来检测外部磁场的应用。 传感器包括交叉耦合的第一和第二分离漏极场效应晶体管（MAGFET），使得垂直于MAGFET的沟道区的外部磁场引起通过每个MAGFET的一个分流漏极半部的电流的增加， 并且通过每个MAGFET的另一个分裂漏极半部的电流减小。 传感器还包括耦合在MAGFET之间的高增益差分放大器，用于检测通过相应的分开漏极半部分传导的电流的变化，并且产生在将外部磁场施加到可植入医疗装置时改变的输出电压。 磁性传感器在诸如心脏起搏器的可植入医疗设备中可用的低电源电压和偏置电流下工作，使得电流消耗和功率消耗最小化。

    Determining intercardiac impedance
    5.
    发明授权
    Determining intercardiac impedance 有权
    确定心脏阻力

    公开(公告)号：US08478402B2

    公开(公告)日：2013-07-02

    申请号：US12263346

    申请日：2008-10-31

    申请人： John D. Wahlstrand ,  Timothy J. Denison ,  Wesley A. Santa

    发明人： John D. Wahlstrand ,  Timothy J. Denison ,  Wesley A. Santa

    IPC分类号： A61N1/00

    CPC分类号： A61B5/053 ,  A61B5/026 ,  A61B5/0538 ,  A61B5/6846 ,  A61B5/7217 ,  A61N1/36521

    摘要： A system and method for determining complex intercardiac impedance to detect various cardiac functions are disclosed involving a signal generator means for providing an adjustable direct current signal, a modulator for modulating the adjustable direct current signal to produce a modulated signal, at least one electrode for propagating the modulated signal across a myocardium, at least one sensor for detecting an outputted modulated signal from the myocardium, and at least one circuit to reduce the influence of process noise (aggressors) in the outputted modulated signal. The at least one circuit comprises an amplifier, a demodulator, and an integrator. The amplitude and phase of the final outputted modulated signal indicate the complex impedance of the myocardium. Changes in the complex impedance patterns of the myocardium provide indication of reduced oxygen and blood flow to the myocardium. The apparatus can be employed in implantable devices, including cardiac pacemakers and implantable cardioverter defibrillators.

    摘要翻译： 公开了一种用于确定复杂心脏阻抗以检测各种心脏功能的系统和方法，其涉及用于提供可调节直流电流信号的信号发生器装置，用于调制可调直流电信号以产生调制信号的调制器，用于传播的至少一个电极 跨越心肌的调制信号，用于检测来自心肌的输出的调制信号的至少一个传感器，以及至少一个电路，以减少输出的调制信号中的过程噪声（侵略者）的影响。 所述至少一个电路包括放大器，解调器和积分器。 最终输出的调制信号的振幅和相位表示心肌的复阻抗。 心肌复合阻抗模式的变化提供氧气和血液流向心肌的指示。 该装置可用于可植入装置，包括心脏起搏器和可植入的心律转复除颤器。

    Apparatus and method to discriminate between telemetry downlink signals and noise in an implanted device
    9.
    发明授权
    Apparatus and method to discriminate between telemetry downlink signals and noise in an implanted device 有权
    用于区分遥测下行链路信号和植入设备中的噪声的装置和方法

    公开(公告)号：US06788973B2

    公开(公告)日：2004-09-07

    申请号：US10117550

    申请日：2002-04-02

    申请人： Timothy J. Davis ,  Robert M. Ecker ,  James D. Reinke ,  John D. Wahlstrand

    发明人： Timothy J. Davis ,  Robert M. Ecker ,  James D. Reinke ,  John D. Wahlstrand

    IPC分类号： A61N137

    CPC分类号： A61N1/37211 ,  A61N1/3718 ,  A61N1/37223 ,  A61N1/37276

    摘要： An implanted medical device (IMD) conserves power by discriminating received radio frequency (RF) signals between noise and data based on frequency. Data is processed while noise is attenuated. The IMD operates in a first, relatively low, power mode while not receiving the RF signals, in a second, higher, power mode responsive to receiving RF signals, and operates in still higher power mode when the RF signals' average frequency over a selected period is within a predetermined range. A receiver circuit receives RF signals and discriminates a data signal from noise based on average frequency of the RF signals over selected time periods. The receiver circuit operates in a power-conserving mode unless it receives RF signals, or otherwise operates in a relatively higher-power mode. The receiver transfers signals to a telemetry circuit that operates in a power-conserving mode until it receives a valid data signal to operate in higher power mode.

    摘要翻译： 植入式医疗设备（IMD）通过基于频率鉴别噪声和数据之间的接收射频（RF）信号来节省功率。 在噪声衰减时处理数据。 IMD在第一个相对较低的功率模式下工作，而不响应于接收RF信号而在第二较高功率模式中接收RF信号，并且当RF信号在所选择的频率上的平均频率 期间在预定范围内。 接收机电路接收RF信号，并根据选定时间段内的RF信号的平均频率，将数据信号与噪声区分开。 接收器电路在功率节省模式下工作，除非它接收RF信号，否则以较高功率模式工作。 接收机将信号传送到工作在省电模式的遥测电路，直到接收到有效的数据信号以在较高功率模式下工作。