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    Apparatus and method to discriminate between telemetry downlink signals and noise in an implanted device
    1.
    发明授权
    Apparatus and method to discriminate between telemetry downlink signals and noise in an implanted device 有权
    用于区分遥测下行链路信号和植入设备中的噪声的装置和方法

    公开(公告)号：US06788973B2

    公开(公告)日：2004-09-07

    申请号：US10117550

    申请日：2002-04-02

    申请人： Timothy J. Davis ,  Robert M. Ecker ,  James D. Reinke ,  John D. Wahlstrand

    发明人： Timothy J. Davis ,  Robert M. Ecker ,  James D. Reinke ,  John D. Wahlstrand

    IPC分类号： A61N137

    CPC分类号： A61N1/37211 ,  A61N1/3718 ,  A61N1/37223 ,  A61N1/37276

    摘要： An implanted medical device (IMD) conserves power by discriminating received radio frequency (RF) signals between noise and data based on frequency. Data is processed while noise is attenuated. The IMD operates in a first, relatively low, power mode while not receiving the RF signals, in a second, higher, power mode responsive to receiving RF signals, and operates in still higher power mode when the RF signals' average frequency over a selected period is within a predetermined range. A receiver circuit receives RF signals and discriminates a data signal from noise based on average frequency of the RF signals over selected time periods. The receiver circuit operates in a power-conserving mode unless it receives RF signals, or otherwise operates in a relatively higher-power mode. The receiver transfers signals to a telemetry circuit that operates in a power-conserving mode until it receives a valid data signal to operate in higher power mode.

    摘要翻译： 植入式医疗设备（IMD）通过基于频率鉴别噪声和数据之间的接收射频（RF）信号来节省功率。 在噪声衰减时处理数据。 IMD在第一个相对较低的功率模式下工作，而不响应于接收RF信号而在第二较高功率模式中接收RF信号，并且当RF信号在所选择的频率上的平均频率 期间在预定范围内。 接收机电路接收RF信号，并根据选定时间段内的RF信号的平均频率，将数据信号与噪声区分开。 接收器电路在功率节省模式下工作，除非它接收RF信号，否则以较高功率模式工作。 接收机将信号传送到工作在省电模式的遥测电路，直到接收到有效的数据信号以在较高功率模式下工作。

    Method and apparatus for rate-responsive cardiac pacing using header mounted pressure wave transducer
    6.
    发明授权
    Method and apparatus for rate-responsive cardiac pacing using header mounted pressure wave transducer 失效
    使用头部安装压力波传感器的速率响应心脏起搏方法和装置

    公开(公告)号：US06208900B1

    公开(公告)日：2001-03-27

    申请号：US08623477

    申请日：1996-03-28

    申请人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    发明人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    IPC分类号： A61N1362

    CPC分类号： A61N1/36542 ,  A61N1/3702

    摘要： In a pacemaker, a method and apparatus for providing rate response in proportion to the patient's metabolic demand for cardiac output as determined in response to the patient's breathing rate or respiratory minute ventilation or contraction strength, optionally augmented by the patient's activity level. An implantable pulse generator (IPG) has one or more pacing leads having a proximal end coupled to the IPG and a distal end in contact with a patient's heart. A pressure wave transducer mounted in the IPG in relation to the proximal end of the pacing lead senses pressure waves transmitted from the distal end of the pacing lead to the proximal end thereof. The pressure waves originate from disturbances imparted to the lead by heart contractions and breathing. A further isolated, reference sensor is also incorporated into the IPG in a similar fashion. An activity signal processor is coupled to the pressure wave or reference sensor for providing a patient activity physiologic signal. A respiration signal processor is coupled to said pressure wave and reference transducers for nulling out common mode noise and providing physiologic respiration rate and/or respiratory minute ventilation signals. A contraction strength signal processor is coupled to said pressure wave and reference transducers for nulling out common mode noise and providing physiologic contraction strength signals. Pacing rate control circuitry is responsive to one or more of the physiologic signals for setting the pacing rate to meed the metabolic demand.

    摘要翻译： 在起搏器中，一种方法和装置，用于根据患者的呼吸频率或呼吸分钟通气或收缩强度确定的与患者的心输出量的代谢需求成比例地提供速率响应，可选地由患者的活动水平增加。 植入式脉冲发生器（IPG）具有一个或多个起搏引线，其具有耦合到IPG的近端和与患者心脏接触的远端。 安装在IPG中的相对于起搏引线的近端的压力波换能器感测从起搏引线的远端传递到其近端的压力波。 压力波起源于通过心脏收缩和呼吸引起的引起的干扰。 另一个隔离的参考传感器也以类似的方式并入到IPG中。 活动信号处理器耦合到压力波或参考传感器，以提供患者活动生理信号。 呼吸信号处理器耦合到所述压力波和参考换能器，用于消除共模噪声并提供生理呼吸速率和/或呼吸分钟通气信号。 收缩强度信号处理器耦合到所述压力波和参考换能器，用于消除共模噪声并提供生理收缩强度信号。 起搏速率控制电路响应于一个或多个生理信号，用于将起搏速率设定为代谢需求。

    Detection of pressure waves transmitted through catheter/lead body
    7.
    发明授权
    Detection of pressure waves transmitted through catheter/lead body 失效
    检测通过导管/铅体传输的压力波

    公开(公告)号：US5899927A

    公开(公告)日：1999-05-04

    申请号：US953092

    申请日：1997-10-17

    申请人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    发明人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    IPC分类号： A61B5/0215 ,  A61B5/08 ,  A61N1/365 ,  A61N1/37 ,  A61B5/00

    CPC分类号： A61N1/3702 ,  A61N1/36514

    摘要： In an implanted medical device, a method and apparatus for detecting pressure waves caused by movement of a body organ, muscle group, limb or the like and transmitted through a catheter or lead body to the implanted medical device employing a pressure wave transducer mounted in relation to the proximal end of the catheter or lead to detect the transmitted pressure waves. The system may also include a reference transducer having the same pressure wave response characteristics as the pressure wave transducer but isolated from the proximal connector end for providing a reference signal including common mode pressure wave noise that both transducers are simultaneously subjected to. The pressure wave signal and the reference signal are preferably amplified, bandpass filtered to the body pressure wave of interest and stored, telemetered out or used to trigger a device operation. The pressure and reference wave transducers preferably are piezoelectric crystal transducers or accelerometers in direct or indirect mechanical contact with the proximal connector end of the catheter and is encapsulated from the body within a device connector assembly. Preferably, the catheter is a lead extending into direct or indirect contact with the patient's heart. Cardiac pressure waves and respiration pressure waves are both transmitted proximally through the lead body to the pressure wave transducer. Pressure wave signals may be derived in parallel to detect particular characteristics of the cardiac and/or respiratory cycle to provide timing signal(s) for controlling the device operations.

    摘要翻译： 在植入式医疗装置中，一种用于检测由身体器官，肌肉群，肢体等的运动引起的透射通过导管或引线体引起的植入医疗装置的压力波的方法和装置，所述压力波换能器安装在关系上 到导管的近端或导致检测传输的压力波。 该系统还可以包括具有与压力波传感器相同的压力波响应特性但与近端连接器端隔离的参考换能器，用于提供包括两个换能器同时经受的共模压力波噪声的参考信号。 压力波信号和参考信号优选被放大，带通滤波到感兴趣的体压波，并被存储，遥测或用于触发装置操作。 压力和参考波传感器优选地是与导管的近端连接器端直接或间接机械接触的压电晶体换能器或加速度计，并且在设备连接器组件内从主体封装。 优选地，导管是延伸成与患者心脏直接或间接接触的导线。 心脏压力波和呼吸压力波都通过引导体向近端传递到压力波传感器。 可以并行导出压力波信号以检测心脏和/或呼吸周期的特定特征，以提供用于控制装置操作的定时信号。

    Verification of capture using pressure waves transmitted through a pacing lead
    8.
    发明授权
    Verification of capture using pressure waves transmitted through a pacing lead 失效
    使用通过起搏引线传输的压力波进行捕获验证

    公开(公告)号：US5702427A

    公开(公告)日：1997-12-30

    申请号：US623443

    申请日：1996-03-28

    申请人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    发明人： Robert M. Ecker ,  Lawrence C. McClure ,  John D. Wahlstrand

    IPC分类号： A61N1/365 ,  A61N1/37 ,  A61N1/375

    CPC分类号： A61N1/3702 ,  A61N1/36542 ,  A61N1/3712 ,  A61N1/36578

    摘要： A capture verification system for a cardiac pacemaker comprising an implantable pulse generator (IPG) and one or more pacing leads having a proximal end coupled to the IPG and a distal end in contact with a patient's heart. The capture verification system employs a pressure wave sensor mounted in the IPG in relation to the proximal end of the pacing lead for sensing pressure waves transmitted from the distal end of the pacing lead to the proximal end thereof. The pressure waves include characteristic sounds of heart contraction and/or distal end lead motion caused by the contraction motion of the patient's heart that are transmitted along the lead body to the active sensor. A further isolated, reference sensor is also incorporated into the IPG in a similar fashion. Signal processors are coupled to the pressure wave and reference sensors for nulling out common mode noise.

    摘要翻译： 一种用于心脏起搏器的捕获验证系统，包括可植入脉冲发生器（IPG）和一个或多个起搏引线，其具有耦合到IPG的近端和与患者心脏接触的远端。 捕获验证系统使用安装在IPG中的压力波传感器相对于起搏引线的近端，用于感测从起搏引线的远端传递到其近端的压力波。 压力波包括由沿着引导体传递到有源传感器的患者心脏的收缩运动引起的心脏收缩和/或远端引导运动的特征性声音。 另一个隔离的参考传感器也以类似的方式并入到IPG中。 信号处理器耦合到压力波和参考传感器，以消除共模噪声。

    Implantable medical lead
    9.
    发明授权
    Implantable medical lead 有权
    可植入医用铅

    公开(公告)号：US08005551B2

    公开(公告)日：2011-08-23

    申请号：US12350382

    申请日：2009-01-08

    申请人： Hugo A. Belacazar ,  James D. Reinke ,  Robert M. Ecker

    发明人： Hugo A. Belacazar ,  James D. Reinke ,  Robert M. Ecker

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36514 ,  A61B5/02055 ,  A61B5/145 ,  A61B5/14532 ,  A61N1/05 ,  A61N1/056

    摘要： An implantable medical lead includes a device, such as a physiological sensor, that is coupled to one or more stimulation/sensing sensing conductors within the lead. When the implantable medical lead is coupled to an implantable medical device, the device carried by the lead both receives power from, and communicates with the implantable medical device via the one or more stimulation/sensing sensing conductors. Each of the one or more stimulation/sensing sensing conductors is also coupled to an electrode that is exposed to body tissue.

    摘要翻译： 可植入医疗引线包括耦合到引线内的一个或多个刺激/感测感测导体的装置，例如生理传感器。 当可植入医疗引线连接到可植入医疗设备时，由引线承载的设备都经由一个或多个刺激/感测感测导体从可植入医疗设备接收电力并与可植入医疗设备进行通信。 一个或多个刺激/感测感测导体中的每一个还耦合到暴露于身体组织的电极。

    Implantable medical device communication system
    10.
    发明授权
    Implantable medical device communication system 失效
    植入式医疗器械通讯系统

    公开(公告)号：US07013178B2

    公开(公告)日：2006-03-14

    申请号：US10254236

    申请日：2002-09-25

    申请人： James D. Reinke ,  Robert M. Ecker

    发明人： James D. Reinke ,  Robert M. Ecker

    IPC分类号： A61N1/37 ,  A61B5/04

    CPC分类号： A61N1/372 ,  A61N1/025

    摘要： An implantable medical device communication system communicates information between an implantable medical device and at least one slave device by way of a two-wire bus. Slave devices may include remote sensors and other implantable medical devices. The implantable medical device includes a communication unit to combine data and power for transmission over the two wire bus. The transmitted signal is selectively changeable between a first and second voltage. The slave device includes a recovery unit to recover data and power from the received signal. An extendable command set includes long commands to set up the system and shorter commands to conserve power. Selectively addressable multicast commands, and shortened quick trigger commands conserve power by lowering system current and increasing data throughput.

    摘要翻译： 可植入医疗装置通信系统通过两线总线在可植入医疗装置与至少一个从属装置之间传送信息。 从设备可以包括远程传感器和其他可植入医疗设备。 该可植入医疗装置包括一个通信单元，用于组合数据和电力以便在两条总线上进行传输。 发射信号可以在第一和第二电压之间有选择地改变。 从设备包括恢复单元，用于从接收到的信号恢复数据和功率。 可扩展命令集包括设置系统的长命令和较短的命令以节省功耗。 选择性寻址的组播命令，缩短的快速触发命令通过降低系统电流和增加数据吞吐量来节省功耗。