公开(公告)号：US20060052416A1

公开(公告)日：2006-03-09

申请号：US11202927

申请日：2005-08-11

申请人： John Dickson ,  Carl Hodge ,  Jose Mendoza ,  Ke Chen

发明人： John Dickson ,  Carl Hodge ,  Jose Mendoza ,  Ke Chen

IPC分类号： A61K31/4709 ,  A61K31/4439 ,  A61K31/426 ,  C07D417/02

CPC分类号： C07D417/04 ,  C07D277/46 ,  C07D417/12 ,  C07D417/14

摘要： 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

摘要翻译： 公开了具有ATP利用酶抑制活性的2-酰氨基-4-取代 - 芳基 - 噻唑基化合物，使用显示出ATP-利用酶抑制活性的化合物的方法，以及包含显示出ATP-利用酶抑制活性的化合物的组合物。

公开(公告)号：US20070287706A1

公开(公告)日：2007-12-13

申请号：US11803140

申请日：2007-05-10

申请人： John Dickson ,  Ke Chen ,  Carl Hodge

发明人： John Dickson ,  Ke Chen ,  Carl Hodge

IPC分类号： A61K31/47 ,  A61K31/538 ,  A61P11/06 ,  A61P17/06 ,  A61P19/02 ,  A61P25/16 ,  A61P25/28 ,  A61P27/02 ,  A61P27/06 ,  A61P3/04 ,  A61P3/10 ,  A61P31/04 ,  A61P31/10 ,  A61P31/12 ,  A61P35/00 ,  A61P35/02 ,  A61P9/00 ,  C07D215/227 ,  C07D265/36

CPC分类号： C07D215/227 ,  C07D215/22

摘要： Certain quinolone-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

摘要翻译： 公开了一些具有ATP利用酶抑制活性的喹诺酮类化合物，使用表现出ATP-利用酶抑制活性的化合物的方法，以及包含表现出ATP-利用酶抑制活性的化合物的组合物。

公开(公告)号：US11604926B2

公开(公告)日：2023-03-14

申请号：US16798277

申请日：2020-02-21

申请人： Ramaswamy Venkateshwaran ,  Sridevi Ramaswamy ,  Priya Rani ,  Huanchen Li ,  Ke Chen

发明人： Ramaswamy Venkateshwaran ,  Sridevi Ramaswamy ,  Priya Rani ,  Huanchen Li ,  Ke Chen

IPC分类号： G06F40/30 ,  G06F16/35 ,  G06F40/117 ,  G06F16/33 ,  G06V10/40 ,  G06V30/10

摘要： A computerized method for reducing domain noise, creating and summarizing human-written sentences into clusters for efficient tagging in natural language processing comprising: receiving a typed, handwritten or printed text; implementing an optical character recognition (OCR) process on human written text to generate a digital version of the human written text; splitting the digital version of the typed, handwritten or printed text into an array of sentences, using a sentence splitter to generate a split sentence version; determining a domain of the human written text; based on the domain, implementing a domain noise reduction process on the split sentences version; hierarchically clustering the split sentences version after the domain noise reduction process; and summarizing the clustered sentences and reducing the amount of data to be tagged.

公开(公告)号：US20060181276A1

公开(公告)日：2006-08-17

申请号：US10552359

申请日：2003-04-04

申请人： Hai Yu ,  Misao Baba ,  William Chen ,  Shaohui Shi ,  Ke Chen

发明人： Hai Yu ,  Misao Baba ,  William Chen ,  Shaohui Shi ,  Ke Chen

IPC分类号： G01V3/00

CPC分类号： G01R33/28 ,  G01R33/383

摘要： A magnetic field generator for MRI comprises a generator main body and a covering member for covering the whole generator main body, and the covering member is made of a non-magnetic material, for example a closely woven fabric of stainless steel, aluminum, copper, nylon, cotton, hemp, flax, rubber or plastics, and a fastening member is provided for fastening the covering member to the generator main body, which is formed of a string or a rope made of stainless steel, aluminum, copper, nylon, cotton, hemp, flax, rubber or plastics.

摘要翻译： 用于MRI的磁场发生器包括发电机主体和用于覆盖整个发电机主体的覆盖部件，并且覆盖部件由非磁性材料制成，例如不锈钢，铝，铜， 尼龙，棉花，大麻，亚麻，橡胶或塑料，以及紧固构件，用于将覆盖构件紧固到发电机主体，该发电机主体由不锈钢，铝，铜，尼龙，棉制成的绳或绳 ，麻，亚麻，橡胶或塑料。

公开(公告)号：US06683181B2

公开(公告)日：2004-01-27

申请号：US10288117

申请日：2002-11-05

申请人： Valerie A. Vaillancourt ,  Sandra Staley ,  Audris Huang ,  Richard Allen Nugent ,  Ke Chen ,  Sajiv K. Nair ,  James A. Nieman ,  Joseph Walter Strohbach

发明人： Valerie A. Vaillancourt ,  Sandra Staley ,  Audris Huang ,  Richard Allen Nugent ,  Ke Chen ,  Sajiv K. Nair ,  James A. Nieman ,  Joseph Walter Strohbach

IPC分类号： C07D29503

CPC分类号： C07D471/06 ,  Y02P20/582

摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.

摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。

公开(公告)号：US06525049B2

公开(公告)日：2003-02-25

申请号：US09888283

申请日：2001-06-22

申请人： Valerie A. Vaillancourt ,  Sandra Staley ,  Audris Huang ,  Richard Allen Nugent ,  Ke Chen ,  Sajiv K. Nair ,  James A. Nieman ,  Joseph Walter Strohbach

发明人： Valerie A. Vaillancourt ,  Sandra Staley ,  Audris Huang ,  Richard Allen Nugent ,  Ke Chen ,  Sajiv K. Nair ,  James A. Nieman ,  Joseph Walter Strohbach

IPC分类号： A61K314745

CPC分类号： C07D471/06 ,  Y02P20/582

摘要： The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.

摘要翻译： 本发明提供式I化合物，其可用作抗病毒剂，特别是作为抗疱疹家族病毒的药剂。

公开(公告)号：US5994367A

公开(公告)日：1999-11-30

申请号：US812516

申请日：1997-03-07

申请人： Kuo-Hsiung Lee ,  Ke Chen ,  Sheng-Chu Kuo

发明人： Kuo-Hsiung Lee ,  Ke Chen ,  Sheng-Chu Kuo

IPC分类号： A61K31/4375 ,  A61P17/06 ,  A61P19/06 ,  A61P35/00 ,  A61P43/00 ,  C07D213/74 ,  C07D471/04 ,  A61K31/395 ,  C07D471/02

CPC分类号： C07D213/74 ,  C07D471/04

摘要： The present invention provides compounds of Formula I: ##STR1## wherein A and R.sub.1 -R.sub.8 are defined herein. The compounds of Formula I inhibit the polymerization of tubulin and possess antimitotic activity. The compounds of Formula I may be useful for the treatment of psoriasis, gout, papiloma, warts, and a variety of tumors.

公开(公告)号：US20130108152A1

公开(公告)日：2013-05-02

申请号：US13623469

申请日：2012-09-20

申请人： Yu Deng ,  Ke Chen

发明人： Yu Deng ,  Ke Chen

IPC分类号： G06T7/00

CPC分类号： G06F17/30256 ,  G06F17/3025 ,  G06F17/30259 ,  G06T7/0002 ,  G06T2207/20081 ,  G06T2207/30168

摘要： Image analysis includes: determining, using one or more processors, an image quality score associated with an image, including: determining a foreground and a background in the image; calculating a set of one or more characteristic parameters of the image based on the determined foreground and background; calculating the image quality score based at least in part on the set of characteristic parameters, wherein calculating the image quality score comprises using an image quality computation model that has been pre-trained; and in response to a search query, generating a set of search results that includes a set the images, wherein inclusion of the images or ranking of the search results is based at least in part on image quality scores associated with the set of images.

公开(公告)号：US07595713B2

公开(公告)日：2009-09-29

申请号：US10552359

申请日：2003-04-04

申请人： Hai Yu ,  Misao Baba ,  William E-Wei Chen ,  Shaohui Shi ,  Ke Chen

发明人： Hai Yu ,  Misao Baba ,  William E-Wei Chen ,  Shaohui Shi ,  Ke Chen

IPC分类号： G01R33/20 ,  G01V3/00

CPC分类号： G01R33/28 ,  G01R33/383

摘要： A magnetic field generator for MRI comprises a generator main body and a covering member for covering the whole generator main body, and the covering member is made of a non-magnetic material, for example a closely woven fabric of stainless steel, aluminum, copper, nylon, cotton, hemp, flax, rubber or plastics, and a fastening member is provided for fastening the covering member to the generator main body, which is formed of a string or a rope made of stainless steel, aluminum, copper, nylon, cotton, hemp, flax, rubber or plastics.

摘要翻译： 用于MRI的磁场发生器包括发电机主体和用于覆盖整个发电机主体的覆盖部件，并且覆盖部件由非磁性材料制成，例如不锈钢，铝，铜， 尼龙，棉花，大麻，亚麻，橡胶或塑料，以及紧固构件，用于将覆盖构件紧固到发电机主体，该发电机主体由不锈钢，铝，铜，尼龙，棉制成的绳或绳 ，麻，亚麻，橡胶或塑料。

公开(公告)号：US20090048313A1

公开(公告)日：2009-02-19

申请号：US12167908

申请日：2008-07-03

申请人： John K. Dickson, JR. ,  Carl Nicholas Hodge ,  Jose Serafin Mendoza ,  Ke Chen

发明人： John K. Dickson, JR. ,  Carl Nicholas Hodge ,  Jose Serafin Mendoza ,  Ke Chen

IPC分类号： A61K31/426 ,  A61P3/00 ,  A61P19/00 ,  A61P35/00 ,  A61P9/00

CPC分类号： C07D417/04 ,  C07D277/46 ,  C07D417/12 ,  C07D417/14

摘要： 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

摘要翻译： 公开了具有ATP利用酶抑制活性的2-酰氨基-4-取代 - 芳基 - 噻唑基化合物，使用显示出ATP-利用酶抑制活性的化合物的方法，以及包含显示出ATP-利用酶抑制活性的化合物的组合物。