Dibenzo[a,d]cycloheptenylidene compounds
    8.
    发明授权
    Dibenzo[a,d]cycloheptenylidene compounds 失效
    二苯并[a,d]环庚烯基化合物

    公开(公告)号:US4996321A

    公开(公告)日:1991-02-26

    申请号:US484963

    申请日:1990-02-26

    IPC分类号: C07D211/70 C07D401/10

    CPC分类号: C07D401/10 C07D211/70

    摘要: Various cyproheptadine derivatives sensitize multidrug resistant cells to certain chemotherapeutic agents. As such, these cyproheptadine derivatives are useful as adjuncts in the reversal of multidrug resistance in mammalian tumor cells either as compounds, pharmaceutically acceptable salts, or pharmaceutical composition ingredients in combination with anticancer chemotherapeutic agents or compounds.

    摘要翻译: 各种赛庚啶衍生物使多药耐药细胞对某些化学治疗剂敏感。 因此,这些赛庚啶衍生物作为化合物,药学上可接受的盐或药物组合物成分与抗癌化学治疗剂或化合物组合可用作在哺乳动物肿瘤细胞中逆转多药耐药性的辅助剂。