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公开(公告)号：US5712103A
公开(公告)日：1998-01-27
申请号：US388251
申请日：1995-02-13
申请人： John Leavitt , Robert N. Taylor , Madhu Varma , Simon Shorter
发明人： John Leavitt , Robert N. Taylor , Madhu Varma , Simon Shorter
IPC分类号： G01N33/68 , G01N33/53 , G01N33/537 , G01N33/543
CPC分类号： G01N33/689 , G01N33/6893 , G01N2333/4745 , G01N2800/368
摘要： The present invention provides methods and diagnostic kits for the detection or prediction of preeclampsia. More particularly, the present invention provides for the diagnosis of preeclampsia before the third trimester of pregnancy by detecting reduced levels of Insulin-like Growth Factor Binding Protein 1 (IGFBP-1) in maternal blood.
摘要翻译： 本发明提供了用于检测或预测先兆子痫的方法和诊断试剂盒。 更具体地，本发明通过检测母体血液中胰岛素样生长因子结合蛋白1（IGFBP-1）的降低水平来提供在怀孕第三个三月期之前诊断先兆子痫。
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公开(公告)号：US20060024757A1
公开(公告)日：2006-02-02
申请号：US11193561
申请日：2005-07-29
申请人： Robert Hussa , Simon Shorter
发明人： Robert Hussa , Simon Shorter
IPC分类号： G01N33/567
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译： 提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。 提供了成骨纤维连接蛋白成像方法。 在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。 提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。 还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。 提供了用于检测骨髓纤维连接以选择概念的方法和产品。
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公开(公告)号：US08372581B2
公开(公告)日：2013-02-12
申请号：US13081826
申请日：2011-04-07
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译： 提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。 提供了成骨纤维连接蛋白成像方法。 在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。 提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。 还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。 提供了用于检测骨髓纤维连接以选择概念的方法和产品。
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公开(公告)号：US07943294B2
公开(公告)日：2011-05-17
申请号：US11193789
申请日：2005-07-29
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译： 提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。 提供了成骨纤维连接蛋白成像方法。 在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。 提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。 还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。 提供了用于检测骨髓纤维连接以选择概念的方法和产品。
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公开(公告)号：US20120040356A1
公开(公告)日：2012-02-16
申请号：US13081826
申请日：2011-04-07
IPC分类号： C12Q1/68 , G01N33/566 , G01N33/577
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译： 提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。 提供了成骨纤维连接蛋白成像方法。 在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。 提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。 还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。 提供了用于检测骨髓纤维连接以选择概念的方法和产品。
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公开(公告)号：US20060024723A1
公开(公告)日：2006-02-02
申请号：US11193789
申请日：2005-07-29
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
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公开(公告)号：US20060024724A1
公开(公告)日：2006-02-02
申请号：US11193806
申请日：2005-07-29
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/689 , B01L3/5023 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07K16/18 , C07K16/30 , C12Q1/6834 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/564 , G01N33/57476 , G01N33/6887 , G01N2333/471 , G01N2333/78 , G01N2500/00 , G01N2800/36 , G01N2800/368
摘要： Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided herein, the sample is treated with a reagent and/or contacted with a non-specific binder. Provided are methods for testing subjects to ascertain health and disease status and to assess the risk of developing a disease or condition. Methods for detecting the presence of oncofetal fibronectin indicating molecules by a variety of methods such as immunoassays and mass spectrometry also are provided. Methods and products for detection of oncofetal fibronection for selection of concepti are provided.
摘要翻译： 提供了检测样品中表达分子的支原体纤连蛋白的方法和产品。 提供了成骨纤维连接蛋白成像方法。 在本文提供的一些方法中，用试剂处理样品和/或与非特异性粘合剂接触。 提供了测试受试者以确定健康和疾病状态并评估发展疾病或病症的风险的方法。 还提供了通过各种方法如免疫测定和质谱法检测指示分子的成纤维细胞蛋白的存在的方法。 提供了用于检测骨髓纤维连接以选择概念的方法和产品。
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