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    Peptides, compositions and uses thereof
    3.
    发明授权
    Peptides, compositions and uses thereof 失效
    肽，组合物及其用途

    公开(公告)号：US08614187B2

    公开(公告)日：2013-12-24

    申请号：US13530550

    申请日：2012-06-22

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    Impedance measurement in an active radio frequency transmitter
    4.
    发明授权
    Impedance measurement in an active radio frequency transmitter 有权
    有源射频发射机中的阻抗测量

    公开(公告)号：US08452245B2

    公开(公告)日：2013-05-28

    申请号：US13412661

    申请日：2012-03-06

    申请人： Brian Walker

    发明人： Brian Walker

    IPC分类号： H03C1/62

    CPC分类号： H04B1/0458 ,  H04B17/10

    摘要： A transmitter and method for determining impedance measurement in an active radio frequency transmitter of an antenna are provided. Voltage and current samples are obtained from a modulating signal delivered to an antenna. The voltage and current samples are converted from analog to digital format, and decimation occurs to reduce the number of samples. Complex demodulation is performed of each of the voltage and current samples to baseband levels and decimation of the voltage and current samples is performed to reduce the number of samples. An impedance estimate can then be estimated from the voltage and current samples.

    摘要翻译： 提供了一种用于确定天线的有源射频发射机中的阻抗测量的发射机和方法。 从传送到天线的调制信号获得电压和电流采样。 电压和电流样本从模拟转换为数字格式，并进行抽取以减少样本数量。 执行每个电压和电流采样到基带电平的复杂解调，并执行电压和电流采样的抽取以减少样本数量。 然后可以从电压和电流样本估计阻抗估计。

    PEPTIDES, COMPOSITIONS AND USES THEREOF
    5.
    发明申请
    PEPTIDES, COMPOSITIONS AND USES THEREOF 失效
    肽，组合物及其用途

    公开(公告)号：US20120295851A1

    公开(公告)日：2012-11-22

    申请号：US13530550

    申请日：2012-06-22

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    Peptides, compositions and uses thereof
    6.
    发明授权
    Peptides, compositions and uses thereof 失效
    肽，组合物及其用途

    公开(公告)号：US08217011B2

    公开(公告)日：2012-07-10

    申请号：US12449950

    申请日：2008-03-07

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08 ,  A61L15/16 ,  C07K7/06

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    Impedance measurement in an active radio frequency transmitter
    7.
    发明授权
    Impedance measurement in an active radio frequency transmitter 有权
    有源射频发射机中的阻抗测量

    公开(公告)号：US08213885B2

    公开(公告)日：2012-07-03

    申请号：US12421519

    申请日：2009-04-09

    申请人： Brian Walker

    发明人： Brian Walker

    IPC分类号： H03C1/62

    CPC分类号： H04B1/0458 ,  H04B17/10

    摘要： A transmitter and method for determining impedance measurement in an active radio frequency transmitter of an antenna are provided. Voltage and current samples are obtained from a modulating signal delivered to an antenna. The voltage and current samples are converted from analog to digital format, and decimation occurs to reduce the number of samples. Complex demodulation is performed of each of the voltage and current samples to baseband levels and decimation of the voltage and current samples is performed to reduce the number of samples. An impedance estimate can then be estimated from the voltage and current samples.

    摘要翻译： 提供了一种用于确定天线的有源射频发射机中的阻抗测量的发射机和方法。 从传送到天线的调制信号获得电压和电流采样。 电压和电流样本从模拟转换为数字格式，并进行抽取以减少样本数量。 执行每个电压和电流采样到基带电平的复杂解调，并执行电压和电流采样的抽取以减少样本数量。 然后可以从电压和电流样本估计阻抗估计。

    COMPOUND
    8.
    发明申请
    COMPOUND 有权
    复合

    公开(公告)号：US20120156691A1

    公开(公告)日：2012-06-21

    申请号：US13391868

    申请日：2010-08-26

    申请人： Stella Lorraine Martin ,  Brian Walker

    发明人： Stella Lorraine Martin ,  Brian Walker

    IPC分类号： G01N33/573 ,  C07F9/6561

    CPC分类号： C12Q1/37 ,  C07F9/6561 ,  G01N33/573

    摘要： Alternative methods for the detection and measurement of proteases in biological samples and compounds which allow for such detection are required to allow for rapid and selective identification of these enzymes. Compounds which allow for selective identification of these enzymes are provided with assays and kits for their use.

    摘要翻译： 检测和测量允许进行这种检测的生物样品和化合物中的蛋白酶的替代方法需要允许对这些酶的快速和选择性鉴定。 提供允许选择性鉴定这些酶的化合物具有用于其使用的测定和试剂盒。

    REGENERATIVE ADSORPTION GAS DRYER
    10.
    发明申请
    REGENERATIVE ADSORPTION GAS DRYER 有权
    再生吸附式气体干燥机

    公开(公告)号：US20100212505A1

    公开(公告)日：2010-08-26

    申请号：US12682719

    申请日：2008-10-13

    申请人： Brian Walker ,  Peter Carney

    发明人： Brian Walker ,  Peter Carney

    IPC分类号： B01D53/26 ,  B01D53/04

    CPC分类号： B01D53/261 ,  B01D2259/40001 ,  B01D2259/40003 ,  B01D2259/40086

    摘要： A regenerative adsorption gas dryer has a wet gas inlet, first and second drying towers, and a dried gas outlet. The inlet, towers and outlet are arranged such that, in use, a flow of purge gas regenerates an off-stream one of the towers, while a stream of wet gas from the wet gas inlet enters an on-stream one of the towers to exit that tower as a stream of dried gas which then continues to the dried gas outlet. The roles of the off-stream and on-stream towers are reversible. The dryer further has a first check valve for controlling a stream of dried gas between the first drying tower and the dried gas outlet, and a second check valve for controlling a stream of dried gas between the second drying tower and the dried gas outlet.

    摘要翻译： 再生吸附式气体干燥器具有湿气入口，第一和第二干燥塔以及干燥气体出口。 进口，塔和出口被布置成使得在使用中，净化气体流再生塔的一个离岸塔，而来自湿气入口的湿气流将进入塔内的一个流入塔 将该塔作为干燥气体流，然后继续进行干燥的气体出口。 离线和视频塔的角色是可逆的。 干燥器还具有用于控制第一干燥塔和干燥气体出口之间的干燥气体流的第一止回阀和用于控制第二干燥塔和干燥气体出口之间的干燥气体流的第二止回阀。