公开(公告)号：US6139535A

公开(公告)日：2000-10-31

申请号：US322131

申请日：1999-05-27

申请人： John Patrick Greelis ,  Mikxay Sirivong ,  David G. Matsuura ,  W. Tate Scott ,  Paul F. Zupkas

发明人： John Patrick Greelis ,  Mikxay Sirivong ,  David G. Matsuura ,  W. Tate Scott ,  Paul F. Zupkas

IPC分类号： A61M25/00 ,  A61M25/06 ,  A61M5/00

CPC分类号： A61M25/00 ,  A61M25/0662 ,  A61M2210/1085 ,  A61M2210/1089

摘要： A delivery device and method for delivering a medical device, such as an infuser, into a body cavity are disclosed. The delivery device includes an ejector tube which slidably extends through a handle. The ejector tube is configured for easy insertion through the urethra into the bladder. A hollow inner tube is located within the ejector tube and includes luer fittings at its distal and proximal ends. The luer fitting at the proximal end of the inner tube is coupled to the handle. Movement of the ejector tube relative to the inner tube causes the distal luer fitting to be withdrawn within the ejector tube and can be used to force an infuser attached to the distal luer fitting from the distal luer fitting. Materials can be transported to the infuser from the proximal luer fitting through the inner tube and out through the distal luer connector.

摘要翻译： 公开了一种用于将医疗装置（例如输液器）输送到体腔中的输送装置和方法。 输送装置包括可滑动地延伸穿过手柄的喷射器管。 喷射器管被配置为容易地通过尿道插入膀胱。 中空的内管位于喷射管内，并在其远端和近端包括鲁尔接头。 在内管的近端处的鲁尔接头联接到手柄。 喷射器管相对于内管的移动导致远端鲁尔接头在喷射器管内被拉出，并且可用于迫使从远端鲁尔接头连接到远端鲁棒接头的浸入器。 材料可以通过内管从近端鲁尔接头输送到输注器，并通过远端鲁尔连接器输出。

公开(公告)号：US06171298B2

公开(公告)日：2001-01-09

申请号：US09041475

申请日：1998-03-11

申请人： David G. Matsuura ,  Walter Dean Gillespie ,  John Patrick Greelis ,  Charles Lowell Parsons ,  Mikxay Sirivong ,  Paul F. Zupkas

发明人： David G. Matsuura ,  Walter Dean Gillespie ,  John Patrick Greelis ,  Charles Lowell Parsons ,  Mikxay Sirivong ,  Paul F. Zupkas

IPC分类号： A61K922

CPC分类号： A61M31/002 ,  A61L17/145 ,  A61L27/34 ,  A61L31/10 ,  A61L33/0011 ,  A61L33/0094 ,  A61L33/08 ,  A61M5/152 ,  A61M31/00 ,  A61M2210/1085 ,  C08L5/00

摘要： A drug-infusing device is implanted into a body cavity such as a bladder. The device is implanted in an uninflated, low profile state. After insertion into the body cavity, the device is filled with a substance, such as a drug, and assumes an increased profile. After the device is filled, it is allowed to float freely within the body cavity. Alternatively, the device can be tethered to a wall of the body cavity. The device delivers the drug at a controlled rate over an extended period of time. In order to deliver the drug at a controlled rate, the device preferably has a pressure-responsive valving member. The flow resistance of the valving member is responsive to the pressure at which the drug is stored within the infusing device. The resistance of the valving member decreases as the pressure within the infusing device decreases, thereby providing a resultant controlled flow rate.

摘要翻译： 将药物注入装置植入诸如膀胱的体腔内。 该器件植入未膨胀的低调状态。 在插入体腔后，装置中填充有诸如药物的物质，并呈现增加的外形。 装置装满后，允许在体腔内自由浮动。 或者，该装置可以系在体腔的壁上。 该设备在长时间内以受控的速率递送药物。 为了以受控的速率递送药物，该装置优选地具有压力响应阀构件。 阀构件的流动阻力响应于药物在输注装置内储存的压力。 当输液装置内的压力降低时，阀构件的阻力减小，从而提供合成的受控流量。

公开(公告)号：US06183461B2

公开(公告)日：2001-02-06

申请号：US09395415

申请日：1999-09-14

申请人： David G. Matsuura ,  Walter Dean Gillespie ,  John Patrick Greelis ,  Charles Lowell Parsons ,  Mikxay Sirivong ,  Paul F. Zupkas

发明人： David G. Matsuura ,  Walter Dean Gillespie ,  John Patrick Greelis ,  Charles Lowell Parsons ,  Mikxay Sirivong ,  Paul F. Zupkas

IPC分类号： A61M3100

CPC分类号： A61M31/002 ,  A61M5/152 ,  A61M31/00 ,  A61M2210/1085

摘要： A drug-infusing device is implanted into a body cavity such as a bladder. The device is implanted in an uninflated, low profile state. After insertion into the body cavity, the device is filled with a substance, such as a drug, and assumes an increased profile. After the device is filled, it is allowed to float freely within the body cavity. Alternatively, the device can be tethered to a wall of the body cavity. The device delivers the drug at a controlled rate over an extended period of time. In order to deliver the drug at a controlled rate, the device preferably has a pressure-responsive valving member. The flow resistance of the valving member is responsive to the pressure at which the drug is stored within the infusing device. The resistance of the valving member decreases as the pressure within the infusing device decreases, thereby providing a resultant controlled flow rate.

摘要翻译： 将药物注入装置植入诸如膀胱的体腔内。 该器件植入未膨胀的低调状态。 在插入体腔后，装置中填充有诸如药物的物质，并呈现增加的外形。 装置装满后，允许在体腔内自由浮动。 或者，该装置可以系在体腔的壁上。 该设备在长时间内以受控的速率递送药物。 为了以受控的速率递送药物，该装置优选地具有压力响应阀构件。 阀构件的流动阻力响应于药物在输注装置内储存的压力。 当输液装置内的压力降低时，阀构件的阻力减小，从而提供合成的受控流量。

公开(公告)号：US09826970B2

公开(公告)日：2017-11-28

申请号：US12903187

申请日：2010-10-12

申请人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

发明人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

IPC分类号： A61B17/10 ,  A61B17/08 ,  A61B17/04

CPC分类号： A61B17/0401 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0424 ,  A61B2017/0438

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.

公开(公告)号：US20140046369A1

公开(公告)日：2014-02-13

申请号：US14111523

申请日：2012-04-12

申请人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

发明人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B2017/0408 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61F2/0811 ,  A61F2002/0835 ,  A61F2002/0841 ,  A61F2002/0858 ,  A61F2002/0888

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.

摘要翻译： 本文公开了用于将软组织固定到诸如骨的刚性材料的方法和装置。 描述了一种组织捕获锚，其包括锚固体和扩展器，使得组织可以在锚定器和扩展器上的外表面和骨孔的内表面之间被捕获或压缩，以将组织固定在孔内。 描述了一种骨锚，其包括具有可扩张尖齿的锚固体和将齿伸展成骨的扩张器。 吊具通过骨锚远端的缝合线捕获组织。 还描述了一种插入器，其可以用于将锚固件插入骨骼中并且将锚固器中的吊具移动以扩展锚固件并捕获锚固体和骨骼之间的组织。 描述了允许使用骨锚将组织固定到骨的方法。

公开(公告)号：US08523902B2

公开(公告)日：2013-09-03

申请号：US12697138

申请日：2010-01-29

申请人： Malcolm Heaven ,  Mikxay Sirivong ,  Rudy Pretti ,  Michael Ko ,  John P. Greelis

发明人： Malcolm Heaven ,  Mikxay Sirivong ,  Rudy Pretti ,  Michael Ko ,  John P. Greelis

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B2017/0409 ,  A61B2017/0424

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A bone anchor is described that includes an anchor body with expandable tines and a spreader that expands the tines into bone. Also disclosed is a bone anchor that includes a base and a top such that suture material may be attached to apertures in the anchor top or else compressed between surfaces on the base and top to secure the suture to the anchor. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.

摘要翻译： 本文公开了用于将软组织固定到诸如骨的刚性材料的方法和装置。 描述了一种骨锚，其包括具有可展开的尖齿的锚固体和将齿伸展成骨的扩张器。 还公开了一种骨锚，其包括基部和顶部，使得缝合线材料可以附接到锚固顶部中的孔，或者在基部和顶部上的表面之间被压缩以将缝线固定到锚固件。 描述了允许使用单个骨锚将组织固定到骨头上的方法，或者还使用多于一个骨锚来提供多段缝合材料以压缩大面积的软组织抵抗骨骼。

公开(公告)号：US09968349B2

公开(公告)日：2018-05-15

申请号：US14111523

申请日：2012-04-12

申请人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

发明人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

IPC分类号： A61B17/04 ,  A61F2/08

CPC分类号： A61B17/0401 ,  A61B2017/0408 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61F2/0811 ,  A61F2002/0835 ,  A61F2002/0841 ,  A61F2002/0858 ,  A61F2002/0888

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.

公开(公告)号：US20110112550A1

公开(公告)日：2011-05-12

申请号：US12903187

申请日：2010-10-12

申请人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

发明人： Malcolm Heaven ,  Michael Ko ,  John P. Greelis ,  Mikxay Sirivong

IPC分类号： A61B17/10 ,  A61B17/08

CPC分类号： A61B17/0401 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0424 ,  A61B2017/0438

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.

摘要翻译： 本文公开了用于将软组织固定到诸如骨的刚性材料的方法和装置。 描述了一种组织捕获锚，其包括锚固体和扩展器，使得组织可以在锚定器和扩展器上的外表面和骨孔的内表面之间被捕获或压缩，以将组织固定在孔内。 描述了一种骨锚，其包括具有可扩张尖齿的锚固体和将齿伸展成骨的扩张器。 吊具通过骨锚远端的缝合线捕获组织。 还描述了一种插入器，其可以用于将锚固件插入骨骼中并且将锚固器中的吊具移动以扩展锚固件并捕获锚固体和骨骼之间的组织。 描述了允许使用单个骨锚将组织固定到骨头上的方法，或者还使用多于一个骨锚来提供多段缝合材料以压缩大面积的软组织抵抗骨骼。

公开(公告)号：US20100198258A1

公开(公告)日：2010-08-05

申请号：US12697138

申请日：2010-01-29

申请人： Malcolm Heaven ,  Mikxay Sirivong ,  Rudy Pretti ,  Michael Ko ,  John P. Greelis

发明人： Malcolm Heaven ,  Mikxay Sirivong ,  Rudy Pretti ,  Michael Ko ,  John P. Greelis

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B2017/0409 ,  A61B2017/0424

摘要： Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. Also disclosed is a bone anchor that comprises a base and a top such that suture material may be attached to apertures in the anchor top or else compressed between surfaces on the base and top to secure the suture to the anchor. Also described is an inserter that can be used to insert the bone anchor into bone and move the spreader relative to the anchor body attach suture material. Also described is an inserter that can be used to insert the bone anchor into bone and move the anchor top relative to the anchor body or anchor base to attach to or clamp suture material there between. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.

摘要翻译： 本文公开了用于将软组织固定到诸如骨的刚性材料的方法和装置。 描述了一种骨锚，其包括具有可扩张尖齿的锚固体和将齿伸展成骨的扩张器。 还公开了一种骨锚，其包括基部和顶部，使得缝合材料可以附接到锚顶部中的孔或者在基部和顶部上的表面之间被压缩以将缝合线固定到锚固体。 还描述了一种插入器，其可以用于将骨锚固件插入骨骼中并相对于锚固体附接缝合材料移动撒布机。 还描述了一种插入器，其可以用于将骨锚固件插入骨骼中并相对于锚固体或锚固基座移动锚定顶部以在其之间附接或夹紧缝合材料。 描述了允许使用单个骨锚将组织固定到骨头上的方法，或者还使用多于一个骨锚来提供多段缝合材料以压缩大面积的软组织抵抗骨骼。