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公开(公告)号:US20130129740A1
公开(公告)日:2013-05-23
申请号:US13598657
申请日:2012-08-30
申请人: John Telford , Vega Masignani , Maria Scarselli , Guido Grandi , Hervé Tettelin , Claire Fraser
发明人: John Telford , Vega Masignani , Maria Scarselli , Guido Grandi , Hervé Tettelin , Claire Fraser
IPC分类号: C07K14/315
CPC分类号: C07K14/315 , A61K38/00 , A61K39/00 , A61K39/092 , A61K2039/505 , A61K2039/53 , C07K16/1275 , C07K16/40 , C07K2319/00 , C12N9/1088 , C12Y205/01018 , Y02A50/464 , Y02A50/466
摘要: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.
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公开(公告)号:US20120207778A1
公开(公告)日:2012-08-16
申请号:US13398079
申请日:2012-02-16
申请人: John Telford , Vega Masignani , Immaculada Margarit Y Ros , Guido Grandi , Claire Fraser , Hervé Tettelin
发明人: John Telford , Vega Masignani , Immaculada Margarit Y Ros , Guido Grandi , Claire Fraser , Hervé Tettelin
IPC分类号: A61K39/09 , C07K16/12 , C07K7/08 , A61K38/16 , A61P31/04 , C07K7/06 , C07K14/315 , C07H21/04
CPC分类号: C07K14/315 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K2319/00 , Y02A50/464 , Y02A50/466 , Y02A90/22 , Y02A90/26
摘要: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences.
摘要翻译: 本发明提供来自B族链球菌(无乳链球菌)和A型链球菌(化脓链球菌)的蛋白质,包括氨基酸序列和相应的核苷酸序列。
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公开(公告)号:US08039007B2
公开(公告)日:2011-10-18
申请号:US12306920
申请日:2007-06-29
申请人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
发明人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
IPC分类号: A61K39/095 , C07H21/04 , C07K14/22
摘要: Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial meningitis.
摘要翻译: 公开了各种特定的脑膜炎球菌蛋白质。 本发明提供了相关多肽,核酸,抗体和方法。 这些都可以用于治疗或预防脑膜炎球菌引起的疾病和/或感染的药物,例如细菌性脑膜炎。
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公开(公告)号:US08491918B2
公开(公告)日:2013-07-23
申请号:US13272982
申请日:2011-10-13
申请人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
发明人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
IPC分类号: A61K39/095 , C07H21/04 , C07K14/22
摘要: Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial meningitis.
摘要翻译: 公开了各种特定的脑膜炎球菌蛋白质。 本发明提供了相关多肽,核酸,抗体和方法。 这些都可以用于治疗或预防脑膜炎球菌引起的疾病和/或感染的药物,例如细菌性脑膜炎。
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公开(公告)号:US20120027801A1
公开(公告)日:2012-02-02
申请号:US13272982
申请日:2011-10-13
申请人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
发明人: Rino Rappuoli , Claire Fraser , Mariagrazia Pizza , Maria Scarselli , Davide Serruto , Hervé Tettelin
IPC分类号: A61K39/095 , C07K7/06 , A61P37/04 , C07K16/12 , C07H21/04 , A61K38/16 , C07K14/22 , C07K7/08
摘要: Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial meningitis.
摘要翻译: 公开了各种特定的脑膜炎球菌蛋白质。 本发明提供了相关多肽,核酸,抗体和方法。 这些都可以用于治疗或预防脑膜炎球菌引起的疾病和/或感染的药物,例如细菌性脑膜炎。
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