公开(公告)号：US20130056085A1

公开(公告)日：2013-03-07

申请号：US13499199

申请日：2010-09-29

申请人： John Tomasko ,  Paul Goggin ,  Geof Brazier

发明人： John Tomasko ,  Paul Goggin ,  Geof Brazier

IPC分类号： F16K17/14 ,  B21D22/00 ,  B21B3/00

CPC分类号： F16K17/1606 ,  Y10T29/49826 ,  Y10T137/0396 ,  Y10T137/1692 ,  Y10T137/1714 ,  Y10T137/1729 ,  Y10T137/1737 ,  Y10T137/1744 ,  Y10T137/1752

摘要： A rupture disk (20), along with associated methods, is disclosed. More particularly, a miniaturized rupture disk is disclosed, comprising a transition area (23) configured to determine a pressure at which the rupture able portion will rupture. A method for forming a rupture disk is also disclosed, wherein a radius (R) of a transition area is configured to set the burst pressure of the rupture disk. A rupture disk having an indent at its apex (24) and a circular line of weakness configured to improve opening performance is also disclosed. Additionally, a method of relieving pressure in a pressurized system is disclosed, wherein a set of rupture disks is provided, wherein each rupture disk in the set has a different radius of transition area. A rupture disk may be selected from the set and installed based on a burst pressure set by the radius of transition area.

摘要翻译： 公开了一种破裂盘（20）及相关方法。 更具体地，公开了一种小型化的破裂盘，包括被配置为确定破裂能部分将破裂的压力的过渡区域（23）。 还公开了一种用于形成破裂盘的方法，其中过渡区域的半径（R）被配置为设置破裂盘的爆破压力。 还公开了具有在其顶点（24）上具有凹口的破裂盘和被构造成改善开口性能的圆形无虚线。 此外，公开了一种在加压系统中减轻压力的方法，其中提供了一组破裂盘，其中该组中的每个破裂盘具有不同的过渡区域的半径。 破裂盘可以从组中选择并且基于由过渡区域的半径设定的爆破压力来安装。

公开(公告)号：US10436339B2

公开(公告)日：2019-10-08

申请号：US13499199

申请日：2010-09-29

申请人： John Tomasko ,  Paul Goggin ,  Geof Brazier

发明人： John Tomasko ,  Paul Goggin ,  Geof Brazier

IPC分类号： F16K17/40 ,  F16K17/16

摘要： A rupture disk (20), along with associated methods, is disclosed. More particularly, a miniaturized rupture disk is disclosed, comprising a transition area (23) configured to determine a pressure at which the rupture able portion will rupture. A method for forming a rupture disk is also disclosed, wherein a radius (R) of a transition area is configured to set the burst pressure of the rupture disk. A rupture disk having an indent at its apex (24) and a circular line of weakness configured to improve opening performance is also disclosed. Additionally, a method of relieving pressure in a pressurized system is disclosed, wherein a set of rupture disks is provided, wherein each rupture disk in the set has a different radius of transition area. A rupture disk may be selected from the set and installed based on a burst pressure set by the radius of transition area.

公开(公告)号：US09168619B2

公开(公告)日：2015-10-27

申请号：US13767311

申请日：2013-02-14

申请人： Paul Goggin ,  Geoffrey Brazier ,  John Tomasko

发明人： Paul Goggin ,  Geoffrey Brazier ,  John Tomasko

IPC分类号： B23P19/04 ,  F16K37/00 ,  F16K17/16

CPC分类号： B23P19/04 ,  F16K17/16 ,  F16K37/0075 ,  Y10T29/49764 ,  Y10T29/49769 ,  Y10T29/49771 ,  Y10T29/49773

摘要： A system and associated methods of quality control for a pressure relief device are disclosed. More specifically, a system and method including one or more of non-destructive dimensional or visual verification, unique identification (e.g., serialization), and image capture of a pressure relief device or a constituent component of such a device are disclosed. A system and method are disclosed in which a checked physical attribute of a pressure relief device, or component thereof, is compared against a statistically expected attribute to determine whether the device or component is suitable for further manufacture or delivery to a customer.

摘要翻译： 公开了一种用于压力释放装置的系统和相关的质量控制方法。 更具体地，公开了包括非破坏性尺寸或视觉验证，唯一识别（例如，串行化）和压力释放装置或这种装置的组成部件的图像捕获中的一个或多个的系统和方法。 公开了一种系统和方法，其中将压力释放装置或其部件的经检查的物理属性与统计预期的属性进行比较，以确定装置或部件是否适于进一步制造或递送给顾客。

公开(公告)号：US20130205559A1

公开(公告)日：2013-08-15

申请号：US13767311

申请日：2013-02-14

申请人： Paul Goggin ,  Geoffrey Brazier ,  John Tomasko

发明人： Paul Goggin ,  Geoffrey Brazier ,  John Tomasko

IPC分类号： B23P19/04

CPC分类号： B23P19/04 ,  F16K17/16 ,  F16K37/0075 ,  Y10T29/49764 ,  Y10T29/49769 ,  Y10T29/49771 ,  Y10T29/49773

摘要： A system and associated methods of quality control for a pressure relief device are disclosed. More specifically, a system and method including one or more of non-destructive dimensional or visual verification, unique identification (e.g., serialization), and image capture of a pressure relief device or a constituent component of such a device are disclosed. A system and method are disclosed in which a checked physical attribute of a pressure relief device, or component thereof, is compared against a statistically expected attribute to determine whether the device or component is suitable for further manufacture or delivery to a customer.

摘要翻译： 公开了一种用于压力释放装置的系统和相关的质量控制方法。 更具体地，公开了包括非破坏性尺寸或视觉验证，唯一识别（例如，串行化）和压力释放装置或这种装置的组成部件的图像捕获中的一个或多个的系统和方法。 公开了一种系统和方法，其中将压力释放装置或其部件的经检查的物理属性与统计预期的属性进行比较，以确定装置或部件是否适于进一步制造或递送给顾客。

公开(公告)号：US20130192688A1

公开(公告)日：2013-08-01

申请号：US13573419

申请日：2012-09-14

申请人： Paul Goggin

发明人： Paul Goggin

IPC分类号： F16K17/16

CPC分类号： F16K17/162 ,  F16K17/1606 ,  F16K17/1613 ,  F16K17/1626 ,  Y10T137/1692 ,  Y10T137/1729

摘要： A hinge assembly for a rupture disk is disclosed. More particularly, a hinge assembly is disclosed having a first hinge member with a flange body and a collapsible hinge, and a second hinge member with a platform hinge, wherein the collapsible hinge is configured to be positioned between the platform hinge and a rupture disk. A rupture disk hinge is also disclosed, having a flange body and a collapsible hinge extending from the flange body. The collapsible hinge may have an approach extending from the flange body, a platform extending from the approach, and a lip extending from the platform. A rupture disk hinge also is disclosed having a hinge extension that extends along a diameter of a flange body across a central fluid flow path.

摘要翻译： 公开了一种用于破裂盘的铰链组件。 更具体地，公开了一种铰链组件，其具有带有凸缘体和可折叠铰链的第一铰链构件和具有平台铰链的第二铰链构件，其中可折叠铰链被配置为定位在平台铰链和破裂盘之间。 还公开了一种破裂盘铰链，其具有凸缘体和从凸缘体延伸的可折叠铰链。 可折叠铰链可以具有从凸缘体延伸的方法，从该方法延伸的平台以及从平台延伸的唇缘。 公开了一种破裂盘铰链，其具有沿着中心流体流动路径沿凸缘体的直径延伸的铰链延伸部。

公开(公告)号：US20090304812A1

公开(公告)日：2009-12-10

申请号：US12086046

申请日：2006-12-07

申请人： John Staniforth ,  Paul Goggin

发明人： John Staniforth ,  Paul Goggin

IPC分类号： A61K33/38 ,  A61K33/30 ,  A61K31/59 ,  A61K31/505 ,  A61K31/60 ,  A61K31/11 ,  A61K31/437 ,  A61K36/29 ,  A61P17/00 ,  A61M35/00

CPC分类号： A61K9/06 ,  A61K9/0014 ,  A61K47/06 ,  A61K47/14 ,  A61K47/44

摘要： The present invention relates to compositions and applicator devices for providing accurate and localized administration of pharmaceutical compositions containing therapeutic agents to the skin. In particular, the invention relates to compositions which are solid at a temperature of about 250 C or less, and which soften upon continuous contact with the skin of a patient. The present invention allows a user to administer precise doses of a therapeutic agent by highly localized application of the composition to a desired skin region, without contacting surrounding skin regions, or the user's hand.

摘要翻译： 本发明涉及用于向皮肤提供含有治疗剂的药物组合物的精确和局部施用的组合物和施用装置。 特别地，本发明涉及在约250℃或更低的温度下为固体的组合物，并且在与患者的皮肤持续接触时软化。 本发明允许用户通过将组合物高度局部应用于期望的皮肤区域而不接触周围皮肤区域或使用者的手来施用精确剂量的治疗剂。

公开(公告)号：US09453582B2

公开(公告)日：2016-09-27

申请号：US13573419

申请日：2012-09-14

申请人： Paul Goggin

发明人： Paul Goggin

IPC分类号： F16K17/40 ,  F16K17/16

CPC分类号： F16K17/162 ,  F16K17/1606 ,  F16K17/1613 ,  F16K17/1626 ,  Y10T137/1692 ,  Y10T137/1729

摘要： A hinge assembly for a rupture disk is disclosed. More particularly, a hinge assembly is disclosed having a first hinge member with a flange body and a collapsible hinge, and a second hinge member with a platform hinge, wherein the collapsible hinge is configured to be positioned between the platform hinge and a rupture disk. A rupture disk hinge is also disclosed, having a flange body and a collapsible hinge extending from the flange body. The collapsible hinge may have an approach extending from the flange body, a platform extending from the approach, and a lip extending from the platform. A rupture disk hinge also is disclosed having a hinge extension that extends along a diameter of a flange body across a central fluid flow path.

公开(公告)号：US20100034838A1

公开(公告)日：2010-02-11

申请号：US12086047

申请日：2006-12-07

申请人： John Staniforth ,  Paul Goggin

发明人： John Staniforth ,  Paul Goggin

IPC分类号： A61K31/57 ,  A61K39/00 ,  A61P1/08 ,  A61P25/16 ,  A61P25/34 ,  A61K47/14 ,  A61K47/46 ,  A61K47/12 ,  A61K47/44 ,  A61K31/4439 ,  A61K31/137 ,  A61K31/568 ,  A61K31/565

CPC分类号： A61K9/0014 ,  A61K9/06 ,  A61K47/10

摘要： The present invention relates to compositions for transdermal administration of a therapeutic agent for providing a systemic therapeutic effect. In particular, the invention relates to spreadable compositions, or compositions which may be solid at a temperature of about 25° C. or less and have a softening point of not higher than 35° C., wherein transdermal administration of the therapeutic agent may be either rapid or sustained.

摘要翻译： 本发明涉及用于透皮给药治疗剂以提供全身治疗效果的组合物。 特别地，本发明涉及可在约25℃或更低的温度下为固体并且软化点不高于35℃的可固化组合物或组合物，其中治疗剂的透皮给药可以是 快速或持续。

公开(公告)号：US20090215753A1

公开(公告)日：2009-08-27

申请号：US12086043

申请日：2006-12-07

申请人： John Staniforth ,  Paul Goggin

发明人： John Staniforth ,  Paul Goggin

IPC分类号： A61K31/5513 ,  A61P25/08 ,  A61K31/4178 ,  A61K31/435 ,  A61M35/00

CPC分类号： A61K9/0014 ,  A61K47/10 ,  A61K47/14

摘要： The present invention provides pharmaceutical compositions for treating a paediatric mammal, the compositions comprising a therapeutic agent and a pharmaceutically acceptable carrier, the composition being suitable for topical application resulting in transdermal administration of the therapeutic agent and a systemic therapeutic effect. The invention also provides relates uses of the compositions, applicators and kits.

摘要翻译： 本发明提供用于治疗儿科哺乳动物的药物组合物，该组合物包含治疗剂和药学上可接受的载体，所述组合物适用于局部施用，导致治疗剂的透皮给药和全身治疗效果。 本发明还提供了组合物，施用器和试剂盒的用途。

公开(公告)号：US20050002993A1

公开(公告)日：2005-01-06

申请号：US10838044

申请日：2004-05-03

申请人： Paul Goggin ,  Caren Cadra

发明人： Paul Goggin ,  Caren Cadra

IPC分类号： A61K9/00 ,  A61K9/24 ,  A61K9/28 ,  A61K9/48 ,  A61K9/68

CPC分类号： A61K9/0056 ,  A61K9/209 ,  A61K9/2826 ,  A61K9/4816

摘要： A confectionery product for delivering at least one pharmaceutically active agent which includes a hard outer shell and a core comprised of a core material which is or forms a liquid-like to a gel-like substance in the oral cavity and is capable of delivering pharmaceutically active agents to infected and/or irritated tissues of the throat.

摘要翻译： 一种用于递送至少一种药物活性剂的糖食产品，其包括硬外壳和由核心材料构成的核心，所述核心材料在口腔中形成或类似于凝胶状物质的核心材料，并且能够输送药物活性 对喉咙的感染和/或刺激性组织的药剂。