NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME
    1.
    发明申请
    NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME 审中-公开
    具有端接硅氧烷的非反应性,亲水聚合物及其制备和使用方法

    公开(公告)号:US20170051145A1

    公开(公告)日:2017-02-23

    申请号:US15343663

    申请日:2016-11-04

    摘要: The present invention relates to compositions comprising at least one stable, near-monodisperse, non-reactive hydrophilic polymer comprising in said polymer's backbone, a hydrophilic segment having a degree of polymerization of about 10 to about 1000, and a linear silicone segment at at least one terminal end of said non-reactive hydrophilic polymer, wherein said silicone segment comprises between about 6 and about 200 siloxy units, and said non-reactive hydrophilic polymer is associated, via the linear silicone block with a silicone hydrogel. The non-reactive hydrophilic polymers may be incorporated into the formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post formation.

    摘要翻译: 本发明涉及包含至少一种稳定的,近单分散的非反应性亲水聚合物的组合物,其在所述聚合物的主链中包含聚合度为约10至约1000的亲水链段和至少至少具有直链硅氧烷链段 所述非反应性亲水聚合物的一个末端,其中所述硅氧烷部分包含约6至约200个甲硅烷氧基单元,并且所述非反应性亲水聚合物通过具有硅酮水凝胶的线性硅氧烷嵌段缔合。 可将非反应性亲水聚合物掺入制备硅氧烷水凝胶的制剂中,或与硅氧烷水凝胶柱形成物接触。

    POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE

    公开(公告)号:US20210261712A1

    公开(公告)日:2021-08-26

    申请号:US17242948

    申请日:2021-04-28

    摘要: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a byproduct polymer. Also provided are precursors to the polymer compositions, processes for preparation of the polymer compositions, and methods of using the polymer compositions, for instance in medical devices.