TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS

    公开(公告)号:US20180100039A1

    公开(公告)日:2018-04-12

    申请号:US15691829

    申请日:2017-08-31

    IPC分类号: C08J3/075 C08G81/02 G02B1/04

    摘要: Described is a tri-block prepolymer having a chemical structure of [A]-[B]-[C], comprising at least one monovalent reactive group, wherein segment [A] and [C] independently comprise polymeric segments based on a first hydrophilic monomer comprising functionality selected from the group consisting of hydroxyalkyl, alkylamine, and mixtures thereof and optionally a second hydrophilic monomer, and [B] comprises a polymeric segment of at least one silicone-containing macromer and optionally a third hydrophilic monomer comprising functionality selected from the group consisting of hydroxyalkyl, alkylamine, and mixtures thereof and optionally a silicone-containing monomer. These prepolymers may be used alone or in combination with other components in reactive monomer mixtures for making silicone hydrogels and ophthalmic devices made therefrom, including contact lenses.

    Tri-block prepolymers and their use in silicone hydrogels

    公开(公告)号:US10676575B2

    公开(公告)日:2020-06-09

    申请号:US15691829

    申请日:2017-08-31

    IPC分类号: C08J3/075 C08G81/02 G02B1/04

    摘要: Described is a tri-block prepolymer having a chemical structure of [A]-[B]-[C], comprising at least one monovalent reactive group, wherein segment [A] and [C] independently comprise polymeric segments based on a first hydrophilic monomer comprising functionality selected from the group consisting of hydroxyalkyl, alkylamine, and mixtures thereof and optionally a second hydrophilic monomer, and [B] comprises a polymeric segment of at least one silicone-containing macromer and optionally a third hydrophilic monomer comprising functionality selected from the group consisting of hydroxyalkyl, alkylamine, and mixtures thereof and optionally a silicone-containing monomer. These prepolymers may be used alone or in combination with other components in reactive monomer mixtures for making silicone hydrogels and ophthalmic devices made therefrom, including contact lenses.

    SILICONE HYDROGELS HAVING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY
    10.
    发明申请
    SILICONE HYDROGELS HAVING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY 审中-公开
    具有可靠水含量和氧气渗透性的硅胶水凝胶

    公开(公告)号:US20160103248A1

    公开(公告)日:2016-04-14

    申请号:US14969292

    申请日:2015-12-15

    IPC分类号: G02B1/04

    摘要: The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

    摘要翻译: 本发明涉及一种方法,其包括以下步骤:使包含至少一种含硅氧烷的组分,至少一种亲水组分和至少一种稀释剂的反应性混合物反应以形成具有小于约80的前进接触角的眼科装置 °; 并且在升高的提取温度下使眼科装置与水提取溶液接触,其中所述至少一种稀释剂的沸点比所述提取温度高至少约10°。