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公开(公告)号：US20090326014A1
公开(公告)日：2009-12-31
申请号：US12308923
申请日：2007-06-29
IPC分类号： A61K31/4418 , A61K31/415
CPC分类号： A61K31/00 , A61K31/415 , A61K31/4418
摘要： The present invention refers to the use of 5-HT7 receptor agonists for the treatment of pain and the symptoms of pain, especially certain subtypes of pain like neuropathic pain and inflammatory pain and symptoms involving allodynia and hyperalgesia, the prevention or the prophylaxis of pain and the symptoms of pain, especially certain subtypes of pain like neuropathic pain and inflammatory pain and symptoms involving allodynia and hyperalgesia.
摘要翻译： 本发明涉及5-HT7受体激动剂用于治疗疼痛和疼痛症状，特别是疼痛的某些亚型，如神经性疼痛和炎性疼痛以及涉及异常性疼痛和痛觉过敏的症状，预防或预防疼痛和 疼痛的症状，特别是某些亚型的疼痛，如神经性疼痛和炎性疼痛以及涉及异常性疼痛和痛觉过敏的症状。
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2.发明申请Heterocyclyl-substituted-ethylamino-phenyl derivatives, their preparation and use as medicaments 审中-公开杂环取代的 - 乙基氨基 - 苯基衍生物，它们的制备和用作药物公开(公告)号：US20100152252A1
公开(公告)日：2010-06-17
申请号：US12520463
申请日：2007-12-21
IPC分类号： A61K31/415 , C07D231/12 , C07C211/27 , C07C217/56 , C07D261/08 , C07D213/64 , A61K31/137 , A61K31/42 , A61K31/4418 , A61P25/00 , A61P25/06 , A61P25/22 , A61P9/12 , A61P1/00 , A61P29/00 , A61P13/00
CPC分类号： C07D231/12 , C07C211/27 , C07C211/29 , C07C217/60 , C07D261/08
摘要： The present invention relates to heterocyclyl-substituted-ethylamino-phenyl compounds of general formula (I), wherein K-L-M-N, Z and R1, R2, R3, R4 are as described in the claims methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals.
摘要翻译： 本发明涉及通式（I）的杂环基取代的 - 乙基氨基 - 苯基化合物，其中KLMN，Z和R1，R2，R3，R4如权利要求的制备方法所述，包含这些化合物的药物以及 它们用于制备用于治疗人或动物的药物的用途。
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3.发明申请公开(公告)号：US20100197717A1
公开(公告)日：2010-08-05
申请号：US12451717
申请日：2008-05-27
申请人： Luz Romero-Alonso , Daniel Zamanillo-Castanedo , José-Miguel Vela-Hernandez , Helmut H. Buschmann
发明人： Luz Romero-Alonso , Daniel Zamanillo-Castanedo , José-Miguel Vela-Hernandez , Helmut H. Buschmann
IPC分类号： A61K31/485 , A61P25/00
CPC分类号： A61K45/06 , A61K31/415 , A61K31/485 , A61K2300/00
摘要： The present invention refers to a combination of a 5HT7 receptor ligand and an opioid receptor ligand, especially of a 5HT7 receptor agonist and an opioid receptor agonist, a medicament comprising this combination, or the use of this combination for the treatment of the symptoms of pain, the prevention or the prophylaxis of the symptoms of pain.
摘要翻译： 本发明涉及5HT7受体配体和阿片受体配体，特别是5HT7受体激动剂和阿片受体激动剂的组合，包含该组合的药物，或该组合用于治疗疼痛症状的组合 ，预防或预防疼痛症状。
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