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公开(公告)号：US20090035250A1
公开(公告)日：2009-02-05
申请号：US11890154
申请日：2007-08-03
CPC分类号： A61K31/74 , A61K31/77 , A61K33/06 , A61K45/06 , A61K2300/00
摘要： Compositions, methods and kits to be used as a lubricant and for treatment of a cavity pathology including joint pathology are provided. The composition comprises therapeutically effective amounts of at least one bioactive agent, such as magnesium compound, at least one lubricating agent, such as hyaluronic acid, and at least one cell membrane repairing agent, such as polyethylene glycol. The components of these compositions may be administered by a direct application, an application through a cannula, an intra-articular injection, as a flush fluid during an arthroscopy of the affected area, as a post-arthroscopy injection, or as part of a lavage of the area affected by the intra-articular pathology. In addition, the composition of the present invention may be administered to the patient from a pump or a depot.
摘要翻译： 提供了用作润滑剂的组合物，方法和试剂盒以及用于治疗包括关节病理学在内的腔病理学。 组合物包含治疗有效量的至少一种生物活性剂，例如镁化合物，至少一种润滑剂，例如透明质酸，和至少一种细胞膜修复剂，例如聚乙二醇。 这些组合物的组分可以通过直接应用，通过插管施用，关节内注射，作为受影响区域的关节镜检查期间的冲洗液，作为关节内窥镜注射后或作为灌洗液的一部分施用 的受关节内病变影响的区域。 此外，本发明的组合物可以从泵或贮库给予患者。
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2.发明授权Compositions for enhancing the viability of animal cells, tissues, and organ explants comprising two low molecular weight PEGs 有权用于增强包含两种低分子量PEG的动物细胞，组织和器官移植物的活力的组合物公开(公告)号：US08927202B2
公开(公告)日：2015-01-06
申请号：US12950368
申请日：2010-11-19
IPC分类号： A01N1/02
CPC分类号： A01N1/0226 , A01N1/02 , A01N1/021 , C12N5/0018 , C12N2500/30 , C12N2500/46 , C12N2500/60
摘要： Disclosed are compositions and methods for the preservation, storage, and transport of living biological tissues, organs, and populations of isolated cells. In particular, the disclosed compositions and processes permit mammalian cells, tissues, and organs to be harvested from suitable donor animals, stored for prolonged periods, and transported to the site of recipient implantation, all without significant loss of cell viability, biological activity, and/or tissue integrity.
摘要翻译： 公开了用于保存，储存和运输生物体组织，器官和分离细胞群体的组合物和方法。 特别地，所公开的组合物和方法允许哺乳动物细胞，组织和器官从合适的供体动物中收获，长时间储存并转运到受体植入部位，所有细胞，组织和器官都不会显着损失细胞活力，生物活性和 /或组织完整性。
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公开(公告)号：US08354221B2
公开(公告)日：2013-01-15
申请号：US13033908
申请日：2011-02-24
IPC分类号： A01N1/00
摘要： Disclosed are methods for the preservation and storage of living biological tissues, organs, and populations of isolated cells. Also disclosed are compositions and methods to permit biological samples (including e.g., cells, cell cultures, tissues, and organs) to be harvested from suitable donor animals, stored for prolonged periods under refrigerated, cryogenic, or near-freezing, and then transported and implanted into a site within the body of a selected recipient animal, all without significant loss of cellular viability, tissue integrity, and/or biochemical function of the stored biological sample.
摘要翻译： 公开了用于保存和储存活的生物组织，器官和分离细胞群体的方法。 还公开了允许从合适的供体动物收获生物样品（包括例如细胞，细胞培养物，组织和器官）的组合物和方法，在冷藏，低温或近冷冻下长时间储存，然后运输和 植入选定受体动物体内的部位，所有这些都不会显着损失存储的生物样品的细胞活力，组织完整性和/或生物化学功能。
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公开(公告)号：US08678821B2
公开(公告)日：2014-03-25
申请号：US12857715
申请日：2010-08-17
IPC分类号： A61C8/00
CPC分类号： A61C8/0006 , A61C8/0033 , A61C8/0092
摘要： An implant includes a collar configured for disposal within tissue. The collar defines an axial bore. A shaft extends between a first end and a second end. The shaft is configured for disposal with the bore of the collar. A base defines an axial bore having an inner surface configured for engagement with the shaft such that the base is axially movable relative to the shaft. At least one arm extends between the collar and the base. The at least one arm is movable via axial movement of the base relative to the shaft between a first position and a second position such that the at least one arm is expanded in a configuration to engage tissue. Methods of use are also disclosed.
摘要翻译： 植入物包括构造成在组织内处置的套环。 轴环限定轴向孔。 轴在第一端和第二端之间延伸。 轴被配置为与套环的孔一起处理。 基部限定轴向孔，其具有构造成用于与轴接合的内表面，使得基座相对于轴可轴向移动。 至少一个臂在套环和底座之间延伸。 所述至少一个臂可以通过所述基座相对于所述轴在第一位置和第二位置之间的轴向运动而移动，使得所述至少一个臂在构造中扩张以接合组织。 还公开了使用方法。
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公开(公告)号：US08551098B2
公开(公告)日：2013-10-08
申请号：US12857741
申请日：2010-08-17
IPC分类号： A61B17/16
CPC分类号： A61B17/1659
摘要： A bone scoring device having a body, a scoring member configured to engage a bone surface and a first biasing member connected to and configured to rotate the scoring member is provided. The scoring member being axially movable between a first, non-rotatable position, such that the scoring member is engaged with the body and a second rotatable position such that the scoring member is released from engagement with the body and freely rotates. The scoring member having an abrasive surface to score the surface of the bone in which it is put in contact. A method for using the scoring device as well as a kit including the scoring device are also provided.
摘要翻译： 本发明提供了一种具有身体的骨骼刻痕装置，被配置为接合骨表面的划痕部件和连接到并构造成旋转刻划部件的第一偏压部件。 所述刻痕构件可在第一不可旋转位置之间轴向移动，使得所述刻划构件与所述主体接合，并且所述第二可旋转位置使得所述刻划构件与所述主体脱离接合并自由旋转。 所述评分构件具有研磨表面以对与其接触的骨的表面进行计分。 还提供了使用评分装置的方法以及包括评分装置的工具箱。
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公开(公告)号：US20120045735A1
公开(公告)日：2012-02-23
申请号：US12857683
申请日：2010-08-17
CPC分类号： A61C19/06 , A61B17/8085 , A61B17/809 , A61B2017/00004 , A61B2090/3966 , A61C8/0006 , A61F2/30767 , A61L27/28 , A61L27/54 , A61L2300/414 , A61L2430/12
摘要： A dental implant system includes bone growth promoting material configured for disposal within a body cavity about an implant. A protective element is configured to overlay the bone growth promoting material. Methods of use are also disclosed.
摘要翻译： 牙种植体系统包括骨生长促进材料，所述骨生长促进材料配置成围绕植入体在体腔内处置。 保护元件构造成覆盖骨生长促进材料。 还公开了使用方法。
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公开(公告)号：US09526600B2
公开(公告)日：2016-12-27
申请号：US12839940
申请日：2010-07-20
CPC分类号： A61C19/06 , A61C8/0006 , A61K6/0044 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
摘要： The disclosure describes biodegradable stents and methods for selectively guided tissue regeneration in treating a periodontal defect adjacent to a root of a tooth. The biodegradable stents and methods have a coronal portion and a transverse portion or shelf, which reduce unwanted migration of gingival epithelium, gingival connective tissue, and soft tissue and enable the cementum and periodontal ligament cells to re-establish the periodontal ligament in a proper sequence resulting in a new periodontal attachment.
摘要翻译： 本公开描述了可生物降解的支架和用于选择性地引导组织再生以治疗邻近牙根的牙周缺损的方法。 可生物降解的支架和方法具有冠状部分和横向部分或架子，其减少牙龈上皮，牙龈结缔组织和软组织的不期望的迁移，并使牙骨质和牙周韧带细胞以适当的顺序重新建立牙周韧带 导致新的牙周附着。
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8.发明申请REFLECTED GINGIVAL TISSUE RETRACTOR DEVICE FOR SURGICAL DENTAL PROCEDURES, KIT AND METHOD FOR USE THEREOF 有权用于外科手术的反射的组合式组织退回装置，套件及其使用方法公开(公告)号：US20120196246A1
公开(公告)日：2012-08-02
申请号：US13019429
申请日：2011-02-02
CPC分类号： A61C9/0033
摘要： A gingival tissue retractor for retracting gingival tissue away from tooth and bone during a surgical procedure having an alveolar bone grip having an open frame structure positionable over at least one tooth and along a predetermined segment of an alveolar bone and providing an inward resilient force about opposite sides of the alveolar bone for maintaining position of the gingival retractor; a first gingival reflector having a solid plate structure and attached to a lower section of one side of the alveolar bone grip for providing a primarily downward force to gingival tissue on one side of the alveolar bone; and a second gingival reflector having a solid plate structure and attached to a lower section of another side of the alveolar bone grip for providing a primarily downward force to gingival tissue on another side of the alveolar bone.
摘要翻译： 一种齿龈组织牵缩器，用于在外科手术过程中将牙龈组织远离牙齿和骨骼，所述齿龈组织牵开器具有牙槽骨柄，所述牙槽骨柄具有可在至少一个牙齿上定位并且沿着牙槽骨的预定部分定位的开放框架结构， 用于保持牙龈牵开器位置的牙槽骨侧; 第一齿龈反射器具有固体板结构并且附接到牙槽骨柄的一侧的下部，用于向牙槽骨的一侧上的牙龈组织提供主要向下的力; 以及第二齿龈反射器，其具有固体板结构并且附接到牙槽骨柄的另一侧的下部，以向牙槽骨的另一侧上的牙龈组织提供主要向下的力。
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公开(公告)号：US09012530B2
公开(公告)日：2015-04-21
申请号：US12847403
申请日：2010-07-30
CPC分类号： A61C19/063 , A61K9/00 , A61K9/0063 , A61Q11/00
摘要： The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a biocompatible adhesive for use in an oral environment, wherein the adhesive is in a non-tacky state when dry and becomes adherent upon contact with liquids.
摘要翻译： 本发明涉及一种胶带，特别是用于牙周治疗的胶带或绷带。 生物相容性粘合剂条带包括具有用于口服环境中的生物相容性粘合剂的柔性屏障，其中所述粘合剂在干燥时处于非粘性状态，并且在与液体接触时变得粘附。
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公开(公告)号：US20120172885A1
公开(公告)日：2012-07-05
申请号：US12983544
申请日：2011-01-03
IPC分类号： A61B17/56
CPC分类号： A61B17/92 , A61B17/86 , A61B17/865
摘要： A system for delivering a surgical tack in tissue includes a driver, comprising: a shaft having a slot and a channel; and a handle slidably connected to said shaft and having a driving mechanism, said driving mechanism having a driving pin for providing a downward force through said shaft; and a tack cartridge having a plurality of tacks and adapted to be received in said slot and further adapted to feed said tacks between said driving mechanism and said channel.
摘要翻译： 用于在组织中递送手术钉的系统包括驱动器，包括：具有狭槽和通道的轴; 以及可滑动地连接到所述轴并具有驱动机构的手柄，所述驱动机构具有用于通过所述轴提供向下的力的驱动销; 以及具有多个钉并且适于被容纳在所述槽中的进一步适于在所述驱动机构和所述通道之间进给所述钉的钉仓。
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