3-6 Bis(morpholinoalkylthio)-pyridazines
    3.
    发明授权
    3-6 Bis(morpholinoalkylthio)-pyridazines 失效
    3-6双(吗啉代烷硫基) - 哒嗪

    公开(公告)号:US4118564A

    公开(公告)日:1978-10-03

    申请号:US817935

    申请日:1977-07-22

    IPC分类号: C07D237/18 C07D413/14

    CPC分类号: C07D237/18

    摘要: This invention concerns novel aminoalkylthiopyridazine compounds useful for inhibiting the aggregation of blood platelets in animals and a process for preparing the compounds from an isothiuronium salt generated in situ from an aminoalkyl halide and thiourea. The compounds also have fungicidal and nematocidal properties.

    摘要翻译: 本发明涉及用于抑制动物血小板聚集的新型氨基烷基硫代哒嗪化合物,以及由氨基烷基卤化物和硫脲原位产生的异硫脲鎓盐制备化合物的方法。 这些化合物也具有杀真菌和杀线虫的特性。

    Aminecarbotrithioates and preparation
    5.
    发明授权
    Aminecarbotrithioates and preparation 失效
    氨基二硫代磷酸酯和制备

    公开(公告)号:US4080497A

    公开(公告)日:1978-03-21

    申请号:US409574

    申请日:1973-10-25

    IPC分类号: C07D295/20 C07D265/30

    CPC分类号: C07D295/20

    摘要: A thiolsulfonate is reacted with an aminecarbodithioate salt to given an aminecarbotrithioate product. The products of this invention have biological activity, particularly in controlling microorganisms and other pests.

    摘要翻译: 硫醇磺酸盐与氨基碳二硫酸盐反应,得到氨基硫代硫酸盐产物。 本发明的产品具有生物活性,特别是在控制微生物和其它害虫方面。

    Aminoalkylsulfides, aminoalkylsulfoxides, and aminoalkylsulfones
    8.
    发明授权
    Aminoalkylsulfides, aminoalkylsulfoxides, and aminoalkylsulfones 失效
    氨基烷基硫化物,氨基烷基亚砜和氨基烷基砜

    公开(公告)号:US4281118A

    公开(公告)日:1981-07-28

    申请号:US49029

    申请日:1979-06-18

    CPC分类号: C07D295/088

    摘要: Novel aminoalkylsulfides, aminoalkylsulfoxides and aminoalkylsulfones of the general formula ##STR1## wherein y and z independently represent the integer 0, 1 or 2; a represents the integer 0 or 2; n represents the integer 1, 2, 3 or 4; R.sub.1 independently represent lower alkyl or hydrogen or alternatively R.sub.1 and R.sub.2 taken together with the adjacent nitrogen atom represent a 5 or 6 membered heterocyclic ring which may optionally contain an oxygen atom whereby a morpholino, piperidino, or pyrrolidino grouping is formed; R.sub.3 represents halo such as chloro or bromo, lower alkylthio, arloweralkylthio, arylthio such as 4-methylphenylthio, 4-morpholinylloweralkylthio such as 4-morpholinylpropylthio, lower alkyl or arloweralkylamino such as 4-methoxybenzenemethanamino; R.sub.4 represents hydrogen or lower alkyl. The invention also includes the pharmaceutically-acceptable salts of the compounds described herein.

    摘要翻译: 新型氨基烷基硫醚,氨基烷基亚砜和通式为“IMAGE”的氨基烷基砜,其中y和z独立地表示整数0,1或2; a表示整数0或2; n表示整数1,2,3或4; R1独立地表示低级烷基或氢,或者R1和R2与相邻氮原子一起表示5或6元杂环,其可以任选地含有氧原子,由此形成吗啉代,哌啶子基或吡咯烷子基; R 3表示卤素如氯或溴,低级烷硫基,芳烷硫基,芳硫基如4-甲苯硫基,4-吗啉基低级烷硫基如4-吗啉基丙硫基,低级烷基或芳烷基氨基如4-甲氧基苯甲氨基氨基; R4代表氢或低级烷基。 本发明还包括本文所述化合物的药学上可接受的盐。

    Process for preparing sulfur-containing hydroxy pyrones
    10.
    发明授权
    Process for preparing sulfur-containing hydroxy pyrones 失效
    制备含硫羟基吡咯烷酮的方法

    公开(公告)号:US3931235A

    公开(公告)日:1976-01-06

    申请号:US429313

    申请日:1973-12-28

    IPC分类号: C07D309/38

    CPC分类号: C07D309/38

    摘要: This invention concerns sulfur-containing hydroxy pyrones corresponding to the formula ##SPC1##Wherein M is H or alkali metal, R is methyl, R' is hydrogen, alkyl, phenyl, halophenyl, nitrophenyl, loweralkylphenyl, benzyl, phenethyl, naphthylmethyl, halobenzyl, loweralkylbenzyl, nitrobenzyl, propargyl, allyl, cyclohexyl loweralkyl, (loweralkylthio)-loweralkyl or adamantyl and n is 0 to 2. The compounds are prepared by reacting the mono-alkali metal salt of 4-hydroxy-6-methyl-2-pyrone with an appropriate thiosulfonate, advantageously in the presence of an organic solvent. The compounds have utility as plant growth stunters and as antimicrobial agents.

    摘要翻译: 本发明涉及对应于式WHEREIN M为H或碱金属,R为甲基,R'为氢,烷基,苯基,卤代苯基,硝基苯基,低级烷基苯基,苄基,苯乙基,萘甲基,卤代苄基,低级烷基苄基,硝基苄基 ,炔丙基,烯丙基,环己基低级烷基,(低级烷硫基) - 低级烷基或金刚烷基,n为0至2.通过使4-羟基-6-甲基-2-吡喃酮的单碱金属盐与适当的硫代磺酸酯 有利地在有机溶剂的存在下进行。 这些化合物具有作为植物生长刺激和作为抗微生物剂的作用。