公开(公告)号：US20060067976A1

公开(公告)日：2006-03-30

申请号：US11238532

申请日：2005-09-28

申请人： Joseph Ferraro ,  Lisa Rogers ,  Paul Martakos ,  Theodore Karwoski ,  Steve Herweck ,  Keith Faucher ,  Philip Mcnamara ,  William Quigley ,  Mark Avella ,  Rick Chenel

发明人： Joseph Ferraro ,  Lisa Rogers ,  Paul Martakos ,  Theodore Karwoski ,  Steve Herweck ,  Keith Faucher ,  Philip Mcnamara ,  William Quigley ,  Mark Avella ,  Rick Chenel

IPC分类号： A61F2/00 ,  B05D3/00

CPC分类号： A61K35/60 ,  A61F2/06 ,  A61F13/02 ,  A61F13/023 ,  A61F2250/0067 ,  A61K9/0024 ,  A61K9/06 ,  A61K31/225 ,  A61K31/355 ,  A61K38/13 ,  A61K47/12 ,  A61K47/14 ,  A61L2/07 ,  A61L2/081 ,  A61L2/087 ,  A61L2/206 ,  A61L2/208 ,  A61L27/36 ,  A61L27/3604 ,  A61L27/52 ,  A61L27/54 ,  A61L31/005 ,  A61L31/10 ,  A61L31/145 ,  A61L2202/24 ,  A61L2300/22 ,  A61L2300/252 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2300/42 ,  A61L2300/602 ,  B05D3/067

摘要： A barrier layer and corresponding method of making provide anti-inflammatory and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The barrier layer is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent.

摘要翻译： 阻挡层和相应的制备方法为可植入患者的医疗装置提供抗炎和抗粘附功能。 除了改善的愈合和抗炎反应之外，阻挡层可以与医疗装置结构组合以提供抗粘附特性。 阻挡层通常由天然存在的油或部分天然存在的油形成的油组合物形成，其至少部分固化形成由至少一种脂肪酸化合物衍生的交联凝胶。 此外，油组合物可以包括治疗剂组分，例如药物或其它生物活性剂。

公开(公告)号：US20060173467A1

公开(公告)日：2006-08-03

申请号：US10442482

申请日：2003-05-20

申请人： Theodore Karwoski ,  Mark Avella

发明人： Theodore Karwoski ,  Mark Avella

IPC分类号： A61F2/06

CPC分类号： A61F2/06 ,  A61B17/11 ,  A61B17/3415 ,  A61B17/3468 ,  A61B2017/00243 ,  A61B2017/320044 ,  A61B2017/320056 ,  A61M25/0194

摘要： A tunneling device is provided for implanting a natural tissue vascular graft in a body. The tunneling device may include a flexible sheath to assist in locating the vascular graft in the body. According to one example, a connector having a longitudinal coupler, such as a surgical tie, may be used to locate the natural tissue graft within the sheath. The natural tissue graft can be secured to the surgical tie when the sheath is retracted. Before tunneling, the sheath can be extended to cover the natural tissue graft to protect the natural tissue graft from damage and aid in locating the natural tissue graft in the body. When the natural tissue graft is positioned as desired in the body, the sheath is removed.