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公开(公告)号：US5531679A
公开(公告)日：1996-07-02
申请号：US212226
申请日：1994-03-14
CPC分类号： A61M25/003 , A61M25/0068 , A61M25/0082 , A61N1/0568 , A61M2025/004 , A61M25/007 , A61M25/0075 , Y10S128/12
摘要： A fluidic infusion system introduces a select liquid chemical into the environment surrounding the functional end of an in vivo catheter or probe. The catheter/probe typically has a-sensor or electrode positioned near or at its closed distal end. A plurality of spaced radial openings are formed in an appropriate pattern adjacent to the end of the catheter/probe for introducing the select liquid chemical into the appropriate environment. The catheter/probe has at least one lumen extending through its length for directing the liquid chemical from a controlled pump to the radial openings. The openings are positioned within the catheter/probe so that when the catheter/probe is inserted into the appropriate environment, e.g., within a blood stream inside an artery or vein, the openings are upstream from the sensor or electrode relative to the flow of blood within such environment, thereby allowing the natural flow of blood to carry the liquid chemical from the radial openings to the sensor or probe area, where it can perform its intended function. The openings allow fluid flow therethrough only in one direction--from the lumen to the environment surrounding the catheter/probe. The catheter/probe may include a plurality of lumens for transporting differing liquid chemicals to the concerned environment.
摘要翻译： 流体输注系统将选择的液体化学品引入围绕体内导管或探针的功能端的环境中。 导管/探针通常具有位于其封闭远端附近或位于其封闭远端的传感器或电极。 多个间隔开的径向开口形成为与导管/探针的端部相邻的适当图案，用于将选择的液体化学品引入适当的环境中。 导管/探针具有延伸穿过其长度的至少一个腔，用于将液体化学物质从受控泵引导到径向开口。 开口定位在导管/探针内，使得当导管/探针插入适当的环境中时，例如在动脉或静脉内的血液内，开口在传感器或电极的上游相对于血流 在这种环境中，从而允许血液的自然流动将液体化学品从径向开口运送到传感器或探针区域，在那里它可以执行其预期的功能。 这些开口允许流体仅从一个方向 - 从内腔到围绕导管/探针的环境流动。 导管/探针可以包括用于将不同液体化学物质输送到相关环境的多个内腔。
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公开(公告)号：US5497772A
公开(公告)日：1996-03-12
申请号：US155737
申请日：1993-11-19
申请人： Joseph H. Schulman , Orville R. Rule, III , David I. Whitmoyer , Ronald J. Lebel , Joseph Y. Lucisano , Alfred E. Mann
发明人： Joseph H. Schulman , Orville R. Rule, III , David I. Whitmoyer , Ronald J. Lebel , Joseph Y. Lucisano , Alfred E. Mann
CPC分类号： A61B5/14865 , A61B5/1495 , A61B5/6849 , A61B2562/08 , A61B5/742
摘要： A glucose monitoring system continuously measures the glucose concentration in a patient's blood, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset limits. If not, an audible and/or visual alarm signal is generated. The glucose monitoring system includes a glucose sensor adapted to be inserted into the venous system of the patient, where it responds to blood glucose and produces sensor signals related to the glucose concentration. The sensor signals are delivered through a suitable interconnect cable to a glucose monitor. In one embodiment, the interconnect cable includes a contactless connector that electrically isolates the glucose sensor from the monitor, and reduces the number of conductors required to interface with a plurality of sensors. The glucose monitor interprets the sensor signals by applying a previously determined calibration to quantitatively determine the blood glucose value. The blood glucose value thus determined is then processed in order to determine the rate of change, is stored (to create a history or record), and may also be displayed in large, easy-to-read numerals. Rate of change information (trend) may also be numerically or graphically displayed.
摘要翻译： 葡萄糖监测系统连续测量患者血液中的葡萄糖浓度，提供这种浓度变化率的指示，并确定测量的浓度和变化率是否在某些预设限度内。 如果没有，则产生声音和/或视觉报警信号。 葡萄糖监测系统包括适于插入患者静脉系统中的葡萄糖传感器，其响应于血糖并产生与葡萄糖浓度相关的传感器信号。 传感器信号通过合适的互连电缆传送到葡萄糖监测器。 在一个实施例中，互连电缆包括非接触式连接器，其将葡萄糖传感器与监视器电隔离，并且减少与多个传感器接合所需的导体的数量。 葡萄糖监测器通过应用预先确定的校准来定量地确定血糖值来解释传感器信号。 然后处理如此确定的血糖值以确定变化率，存储（创建历史或记录），并且还可以以大的易于阅读的数字显示。 变化率信息（趋势）也可以数字或图形显示。
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