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27 条记录 (耗时 0.022 秒)

    Porous inorganic ultrasound contrast agents
    1.
    发明授权
    Porous inorganic ultrasound contrast agents 失效
    多孔无机超声对比剂

    公开(公告)号：US5147631A

    公开(公告)日：1992-09-15

    申请号：US693476

    申请日：1991-04-30

    申请人： Joseph L. Glajch ,  Gary L. Loomis ,  Walter Mahler

    发明人： Joseph L. Glajch ,  Gary L. Loomis ,  Walter Mahler

    IPC分类号： A61K49/22

    CPC分类号： A61K49/223 ,  A61K49/225

    摘要： The invention relates to ultrasound contrast agents comprising porous particles of an inorganic material containing an entrapped gas or liquid and having an average particle diameter of about 0.05 to 500 microns, said inorganic material being selected from one or more of the group consisting of: monomeric or polymeric borates; monomeric or polymeric aluminas; monomeric or polymeric carbonates; monomeric or polymeric silicas; and monomeric or polymeric phosphates; and pharmaceutically acceptable organic or inorganic cationic salts thereof.

    摘要翻译： 本发明涉及包含含有截留气体或液体并且平均粒径为约0.05至500微米的无机材料的多孔颗粒的超声造影剂，所述无机材料选自以下组中的一种或多种：单体或 聚合硼酸盐; 单体或聚合氧化铝; 单体或聚合碳酸酯; 单体或聚合二氧化硅; 和单体或聚合磷酸盐; 及其药学上可接受的有机或无机阳离子盐。

    Bioresorbable hydrogel compositions for implantable prostheses
    4.
    发明授权
    Bioresorbable hydrogel compositions for implantable prostheses 失效
    用于可植入假体的生物可再吸收水凝胶组合物

    公开(公告)号：US07442384B2

    公开(公告)日：2008-10-28

    申请号：US11523482

    申请日：2006-09-19

    申请人： Gary L. Loomis ,  D. Christian Lentz

    发明人： Gary L. Loomis ,  D. Christian Lentz

    IPC分类号： A61F2/06 ,  A61K31/40

    CPC分类号： A61K9/2027 ,  A61K9/204 ,  A61L27/34 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L29/16 ,  A61L31/06 ,  A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  A61L2300/236 ,  A61L2300/254 ,  A61L2300/406 ,  A61L2300/408 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/602 ,  A61L2300/604 ,  A61L2300/606 ,  C08G63/664 ,  C08G63/676 ,  C08G64/183 ,  C08L67/00

    摘要： Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers can be effected in solution in organic solvents or in solvent-free systems. If crosslinking occurs in a humid environment, a hydrogel will form. If crosslinking occurs in a non-humid environment, a xerogel will form which will form a hydrogel when exposed to a humid environment and the resulting crosslinked materials form hydrogels when exposed to humid environments. These hydrogels are useful as components in medical devices such as implantable prostheses. In addition, such hydrogels are useful as delivery vehicles for therapeutic agents and as scaffolding for tissue engineering applications.

    摘要翻译： 公开了由水不溶性共聚物形成的交联组合物。 这些组合物是具有每个聚合物链的生物可再吸收区域，亲水区域和至少两个可交联官能团的共聚物。 这些聚合物的交联可以在有机溶剂中的溶液中或在无溶剂体系中进行。 如果交联发生在潮湿环境中，则会形成水凝胶。 如果交联发生在非潮湿环境中，则将形成干凝胶，当暴露于潮湿环境时，将形成水凝胶，并且当暴露于潮湿环境时，得到的交联材料形成水凝胶。 这些水凝胶可用作诸如可植入假体的医疗装置中的部件。 此外，这种水凝胶可用作治疗剂的递送载体和组织工程应用的脚手架。

    Curable composition comprising elastomeric terpolymer of carbon monoxide
    6.
    发明授权
    Curable composition comprising elastomeric terpolymer of carbon monoxide 失效
    包含一氧化碳弹性体三元共聚物的可固化组合物

    公开(公告)号：US4543440A

    公开(公告)日：1985-09-24

    申请号：US587901

    申请日：1984-03-09

    申请人： Gary L. Loomis

    发明人： Gary L. Loomis

    IPC分类号： C08G67/02 ,  C08L73/00

    CPC分类号： C08L73/00 ,  C08G67/02

    摘要： Terpolymers having 1,4-diketo functionalities and a carbonyl group concentration of about 5-20% of polymer weight can be conveniently cured by heating with an aromatic primary diamine or its precursor and a catalytic amount of an acid having a pKa of at most about 3. Cured polymers have good physical properties and are suitable in such applications as, for example hose, tubing, wire coatings, gaskets, and seals.

    摘要翻译： 具有1,4-二酮官能度和羰基浓度为聚合物重量约5-20％的三元共聚物可以方便地通过用芳族伯二胺或其前体加热和催化量的pKa至多约为 3.固化聚合物具有良好的物理性能，适用于诸如软管，管材，电线涂层，垫片和密封件的应用。

    Process for making foamed, sulfur-cured polymer blend compositions
    7.
    发明授权
    Process for making foamed, sulfur-cured polymer blend compositions 失效
    制备泡沫，硫固化聚合物共混组合物的方法

    公开(公告)号：US4540719A

    公开(公告)日：1985-09-10

    申请号：US692634

    申请日：1985-01-18

    申请人： Gary L. Loomis

    发明人： Gary L. Loomis

    IPC分类号： C08L65/00 ,  C08J9/00 ,  C08J9/04 ,  C08J9/06 ,  C08L1/00 ,  C08L23/00 ,  C08L27/00 ,  C08L27/04 ,  C08L27/10 ,  C08L31/00 ,  C08L73/00 ,  C08L81/00 ,  C08L81/06 ,  C08L101/00

    CPC分类号： C08J9/0061 ,  C08J2323/08 ,  C08J2327/02 ,  C08J2423/00 ,  C08J2427/00

    摘要： A blend of an E/X/Y copolymer, where E is ethylene, X is a vinyl ester, and Y is carbon monoxide or sulfur dioxide, with a polymer of vinyl halide or vinylidene halide is foamed and cured by dispersing in the blend a blowing agent and sulfur or a sulfur-releasing agent and heating the blend containing those additives at 100.degree.-180.degree. C. for a sufficient time to produce curing and foaming. This process can be run either continuously or batchwise in conventional equipment under conventional conditions in the presence of air. Plasticizers and other materials which often interfere with peroxide cures can be present in the process of this invention. The foamed and cured products have excellent physical properties and ozone resistance.

    摘要翻译： E / X / Y共聚物的共混物，其中E是乙烯，X是乙烯基酯，Y是一氧化碳或二氧化硫，与乙烯基卤化物或亚乙烯基卤化物的聚合物发泡并通过在共混物a中分散而固化 发泡剂和硫或脱硫剂，并将含有这些添加剂的共混物在100-180℃下加热足够的时间以产生固化和发泡。 这种方法可以在常规设备中在常规条件下在空气存在下连续运行或分批运行。 常常干扰过氧化物固化的增塑剂和其它材料可以存在于本发明的方法中。 发泡和固化产品具有优异的物理性能和耐臭氧性。

    Biodegradable thermoplastic polymer blend compositions with accelerated biodegradation
    9.
    发明授权
    Biodegradable thermoplastic polymer blend compositions with accelerated biodegradation 失效
    具有加速生物降解性的可生物降解的热塑性聚合物共混组合物

    公开(公告)号：US5852114A

    公开(公告)日：1998-12-22

    申请号：US407083

    申请日：1995-03-20

    申请人： Gary L. Loomis ,  Michael J. Izbicki ,  Anthony Flammino

    发明人： Gary L. Loomis ,  Michael J. Izbicki ,  Anthony Flammino

    IPC分类号： C08L23/26 ,  C08F20060101 ,  C08L29/04 ,  C08L101/00 ,  C08L101/12 ,  C08L101/16 ,  C08L23/08 ,  C08L29/02

    CPC分类号： C08L29/04 ,  C08L101/00 ,  C08L2201/06 ,  C08L2205/02

    摘要： Biodegradable thermoplastic polymer blend compositions are presented in which a first polymer and a second polymer are intimately associated together in a uniform, substantially homogeneous blend. The second polymer of the composition acts to facilitate biodegradation of the composition, and of shaped articles manufactured therefrom, at a rate which is enhanced over that of the most slowly biodegrading individual polymer component of the composition. The composition may further comprise a polysaccharide component, such as a starch component like destructurized starch.

    摘要翻译： 提出了可生物降解的热塑性聚合物共混物组合物，其中第一聚合物和第二聚合物以均匀的基本上均匀的共混物紧密地结合在一起。 组合物的第二聚合物用于促进组合物及其制备的成形制品的生物降解，其速率比组合物中缓慢生物降解的单一聚合物组分的速率增强。 组合物还可以包含多糖组分，例如淀粉组分如无序结构淀粉。