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    Chemical depletion signal for a swimming pool chemical dispenser
    3.
    发明授权
    Chemical depletion signal for a swimming pool chemical dispenser 失效
    游泳池化学分配器的化学耗尽信号

    公开(公告)号：US4825528A

    公开(公告)日：1989-05-02

    申请号：US104290

    申请日：1987-10-05

    申请人： Donald Nicholson ,  Robert Nordmyer

    发明人： Donald Nicholson ,  Robert Nordmyer

    IPC分类号： C02F1/68 ,  B29C65/00 ,  B23P11/00

    CPC分类号： C02F1/688 ,  Y10T29/49876 ,  Y10T29/49893

    摘要： A device for use in a swimming pool to continuously dispense chlorine for sanitizing the water is disclosed which provides an indication when the device has either depleted or nearly depleted its chlorine supply. The float supporting the feeder and the chlorine is of two colors, one color on the top and a second color on the bottom. When an adequate amount of chlorine is contained in the feeder, the bottom color is below the waterline and not readily visible, and when the chlorine is depleted to a desired minimum amount, the bottom color is sufficiently above the waterline to provide a readily perceived visual warning of chlorine depletion.

    摘要翻译： 公开了一种用于游泳池连续分配氯以消毒水的装置，其提供了当装置已经耗尽或几乎耗尽其氯气供应的指示。 支撑进料器和氯气的浮子有两种颜色，顶部有一种颜色，底部有一种颜色。 当进料器中含有足够量的氯时，底部颜色低于水线并且不容易看到，当氯消耗到所需的最小量时，底部颜色足够高于水线以提供易于察觉的视觉 警告氯消耗。

    Metering mechanism for a swimming pool chemical dispenser
    5.
    发明授权
    Metering mechanism for a swimming pool chemical dispenser 失效
    游泳池化学分配器的计量机制

    公开(公告)号：US4822571A

    公开(公告)日：1989-04-18

    申请号：US104287

    申请日：1987-10-05

    申请人： Donald Nicholson ,  Robert Nordmyer

    发明人： Donald Nicholson ,  Robert Nordmyer

    IPC分类号： B01F1/00 ,  C02F1/68 ,  B01D12/00

    CPC分类号： C02F1/688 ,  B01F1/0027 ,  C02F2103/42 ,  Y10T137/4891

    摘要： A device for use in a swimming pool to continuously dispense chlorine for sanitizing the water is disclosed which has a metering valve designed for precise adjustment of the rate of dispersion of the chemical contained in the feeder. The metering mechanism is made of two segments, with a metering valve cap fitting over a metering valve body to adjust the apertures in the metering mechanism. Precise control is afforded both by a screw-type adjustment of aperture size and by a prevention of inadvertent readjustment of the metering mechanism caused by the device being bumped.

    摘要翻译： 公开了一种用于游泳池连续分配氯以消毒水的装置，其具有设计用于精确调节包含在给料器中的化学品的分散速率的计量阀。 计量机构由两个部分组成，计量阀盖配合在计量阀体上以调节计量机构中的孔。 通过孔径尺寸的螺旋式调节和通过防止装置被撞击引起的计量机构的意外重新调整来提供精确的控制。

    Method of purification of recombinant human interleukin-5
    6.
    发明授权
    Method of purification of recombinant human interleukin-5 失效
    纯化重组人白介素-5的方法

    公开(公告)号：US5681936A

    公开(公告)日：1997-10-28

    申请号：US466852

    申请日：1995-06-06

    申请人： Donald Nicholson

    发明人： Donald Nicholson

    IPC分类号： C07K14/54 ,  A23J1/00 ,  C07K1/00 ,  C07K14/00 ,  C07K16/00

    CPC分类号： C07K14/5409

    摘要： Disclosed is a method for purifying Human interleukin-5 (IL-5) a single chromatographic step. After removing cells from a cell culture expressing human interleukin-5, IL-5 is purified by first adjusting the culture supernatant to the calculated pI value of mature IL-5 (pI=7.44) and then passing the conditioned supernatant through tandem linked anion- and cation-exchange columns. The resulting pass-through fraction contains the IL-5 and is devoid of all other contaminating proteins. An optional hydrophobic-interaction chromatography step is disclosed for positive selection of IL-5 and in order to concentrate the preparation. Pure IL-5 was recovered with a high overall yield (>90%), was N-glycosylated and was entirely homodimeric.

    摘要翻译： 公开了纯化人白细胞介素-5（IL-5）单色谱步骤的方法。 在从表达人白细胞介素-5的细胞培养物中除去细胞后，通过首先将培养上清液调节至计算的成熟IL-5的pI值（pI = 7.44），然后通过串联连接的阴离子 - 和阳离子交换柱。 所得到的直通级分含有IL-5并且没有所有其它污染蛋白质。 公开了任选的疏水相互作用层析步骤用于阳性选择IL-5并且为了浓缩制剂。 以高总产率（> 90％）回收纯的IL-5，被N-糖基化并且完全是同二聚体。

    Swimming pool chemical dispenser with restraining tether
    7.
    发明授权
    Swimming pool chemical dispenser with restraining tether 失效
    游泳池化学分配器与限制系绳

    公开(公告)号：US4828804A

    公开(公告)日：1989-05-09

    申请号：US104402

    申请日：1987-10-05

    申请人： Donald Nicholson ,  Robert Nordmyer ,  Greg Boyle

    发明人： Donald Nicholson ,  Robert Nordmyer ,  Greg Boyle

    IPC分类号： B01F1/00 ,  C02F1/68 ,  C02F1/76

    CPC分类号： C02F1/688 ,  B01F1/0027 ,  C02F1/76 ,  C02F2103/42

    摘要： A device for use in a swimming pool to prevent a floating chlorine feeder from spending an inordinate amount of time near a single location in a swimming pool due to water currents is disclosed which uses a tether to place the feeder in a central location in the swimming pool. A retainer is attachable to a floating feeder, and a retainer hook is attached to the edge of the pool furthest away from the location to which the feeder is drawn by water currents. A tether cord between the hook and the retainer keeps the feeder in the central location in the pool, where it is maintained by the currents in the pool.

    摘要翻译： 公开了一种用于游泳池的设备，用于防止漂浮的氯气给水器由于水流而在游泳池中的单个位置附近花费过多的时间，其使用系绳将给料器放置在游泳池的中心位置 游泳池 保持器可附接到浮动进料器，并且保持器钩连接到最远离供水器通过水流吸入的位置的池的边缘。 钩和保持器之间的绳索将进料器保持在池中的中心位置，在那里它通过池中的电流来维持。

    Swimming pool chemical dispenser and method of making same
    8.
    发明授权
    Swimming pool chemical dispenser and method of making same 失效
    游泳池化学分配器及其制作方法

    公开(公告)号：US4828803A

    公开(公告)日：1989-05-09

    申请号：US104501

    申请日：1987-10-05

    申请人： Donald Nicholson ,  Robert Nordmyer

    发明人： Donald Nicholson ,  Robert Nordmyer

    IPC分类号： B01F1/00 ,  C02F1/68

    CPC分类号： C02F1/688 ,  B01F1/0027 ,  C02F2103/42 ,  Y10T137/4891

    摘要： A device for use in a swimming pool to continuously dispense chlorine for sanitizing the water is disclosed which is advantageously made of five main segments which may be molded using only simple and inexpensive molds. The device is for the most part snapped together in a manner preventing relative rotation of the various components, with only a single adhesive operation required to seal the waterproof float assembly. The device is manufactured in a sturdy fashion, with all the parts being held firmly together in a unit not dependent on single axis connecting hardware.

    摘要翻译： 公开了一种用于游泳池连续分配用于消毒水的氯的装置，其有利地由可以仅使用简单和便宜的模具模制的五个主要部分制成。 该装置以防止各种部件的相对旋转的方式大部分地卡在一起，只需要密封防水浮子组件所需的单一粘合操作。 该设备以坚固的方式制造，所有部件都牢固地固定在不依赖于单轴连接硬件的单元中。

    Adapter and pole assembly
    9.
    发明授权
    Adapter and pole assembly 失效
    适配器和电极组件

    公开(公告)号：US4819293A

    公开(公告)日：1989-04-11

    申请号：US142175

    申请日：1988-01-11

    申请人： Donald Nicholson

    发明人： Donald Nicholson

    IPC分类号： A46B5/00 ,  A47L13/24 ,  B25G3/18 ,  B25G3/38 ,  E04H4/16 ,  F16D1/10 ,  F16B7/10

    CPC分类号： A46B5/0083 ,  A46B5/0075 ,  A47L13/24 ,  B25G3/18 ,  B25G3/38 ,  E04H4/1609 ,  A46B2200/3073 ,  Y10T16/473 ,  Y10T403/32483

    摘要： The pool cleaning pole assembly includes an elongated cleaning pole having an improved adapter releasably connected to the bottom cleaning end thereof, and a cleaning accessory releasably connected to the adapter. The adapter includes(a) a first member having an upper hollow tubular portion releasably connected in the pole lower end by spring biased pins and bearing a base below the pole, and(b) a second member rotatably secured to the underside of the base for limited rotation. The second member has a bracket to which a pool cleaning accessory such as a brush, vacuum head, etc., is releasably connected. The adapter also includes a pin or the like inserted in aligned openings in the base and second member and connected to a Bowden wire or push rod passing up through the hollow tubular member and pole to the pole's upper end where it can be easily moved up and down by the operator to lock the second member against rotation or free it to rotate. Alternatively, the locking device may be clamp operated by the wire or rod. The adapter and assembly are efficient, inexpensive and durable.

    摘要翻译： 池清洁杆组件包括细长的清洁杆，其具有可释放地连接到其底部清洁端的改进的适配器，以及可拆卸地连接到适配器的清洁附件。 适配器包括（a）第一构件，其具有上部中空管状部分，该中空管状部分通过弹簧偏置的销可释放地连接在杆下端，并且在杆下方支撑底座，以及（b）第二构件，其可旋转地固定到底座的下侧， 限制旋转 第二构件具有可拆卸地连接诸如刷子，真空头等的池清洁附件的支架。 适配器还包括插入基座和第二构件中的对准的开口中的销或类似物，并且连接到通过中空管状构件和杆的鲍登线或推杆，杆至杆的上端，其可以容易地向上移动， 由操作者向下以锁定第二构件以避免旋转或使其旋转。 或者，锁定装置可以由线或杆夹紧操作。 适配器和组件是高效，廉价和耐用的。