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    Lead and delivery system to detect and treat a myocardial infarction region
    1.
    发明申请
    Lead and delivery system to detect and treat a myocardial infarction region 审中-公开
    用于检测和治疗心肌梗死区域的牵引和传递系统

    公开(公告)号：US20070100383A1

    公开(公告)日：2007-05-03

    申请号：US11261202

    申请日：2005-10-28

    申请人： Joseph Pastore ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    发明人： Joseph Pastore ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    IPC分类号： A61N1/36

    CPC分类号： A61N1/0587 ,  A61N1/059 ,  A61N1/3627

    摘要： A method includes mounting an anchor member to a surface of a heart, the anchor member having a tension member coupled to the anchor member, advancing a lead body along the tension member, the lead body including a plurality of electrodes disposed along the lead body, identifying an MI region of the heart, positioning the plurality of electrodes at or near the MI region, affixing the tension member to the lead body to hold the electrodes in position, and delivering pulses through the plurality of electrodes to the heart.

    摘要翻译： 一种方法包括将锚定构件安装到心脏的表面，所述锚定构件具有联接到所述锚定构件的张紧构件，使所述引线体沿着所述张紧构件前进，所述引线主体包括沿着所述引线主体设置的多个电极， 识别心脏的MI区域，将多个电极定位在MI区域处或附近，将张紧构件固定到引线体以将电极保持在适当位置，并且将脉冲通过多个电极传递到心脏。

    Epicardial patch including isolated extracellular matrix with pacing electrodes
    2.
    发明申请
    Epicardial patch including isolated extracellular matrix with pacing electrodes 失效
    心外膜包括分离的细胞外基质与起搏电极

    公开(公告)号：US20060136028A1

    公开(公告)日：2006-06-22

    申请号：US11017627

    申请日：2004-12-20

    申请人： Jeffrey Ross ,  John Kim ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    发明人： Jeffrey Ross ,  John Kim ,  Rodney Salo ,  Ronald Heil ,  Randy Westlund

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587 ,  A61N1/0568 ,  A61N1/059

    摘要： An epicardial patch includes an extracellular matrix (ECM) and a plurality of electrodes. The isolated ECM is configured for epicardial attachment over a myocardial region including an injured area to control post-injury remodeling of the myocardial region. The plurality of electrodes is configured for delivering electrical stimulation to enhance the effect of the isolated ECM in remodeling control by altering workload and stress on the myocardial region.

    摘要翻译： 心外膜贴片包括细胞外基质（ECM）和多个电极。 分离的ECM被配置用于在包括受伤区域的心肌区域上的心外膜附着以控制心肌区域的损伤后重建。 多个电极被配置为通过改变心肌区域上的工作负荷和压力来传递电刺激以增强孤立的ECM在重塑控制中的作用。

    Adhesive elements and methods for accessing the pericardial space
    6.
    发明申请
    Adhesive elements and methods for accessing the pericardial space 审中-公开
    用于进入心包空间的粘合元件和方法

    公开(公告)号：US20060259017A1

    公开(公告)日：2006-11-16

    申请号：US11115647

    申请日：2005-04-27

    申请人： Ronald Heil ,  Randy Westlund ,  Peter Callas

    发明人： Ronald Heil ,  Randy Westlund ,  Peter Callas

    IPC分类号： A61B17/00

    CPC分类号： A61B17/00491 ,  A61B17/3478 ,  A61B2017/00247 ,  A61B2017/005 ,  A61B2018/00392

    摘要： A technique for accessing a pericardial space of a heart includes attaching a grip to a pericardium with adhesive, grasping the grip, drawing the pericardium away from the heart, and perforating the pericardium. The grip may consist solely of an adhesive. In other embodiments, other structures for the grip are used, including anchors, suture loops, and gripping tubes.

    摘要翻译： 用于进入心脏心包空间的技术包括用粘合剂将手柄附接到心包，抓握手柄，将心包牵离心脏，以及穿透心包。 把手可以仅由粘合剂组成。 在其他实施例中，使用用于把手的其他结构，包括锚固件，缝线环和夹紧管。

    Expandable seal for use with medical device and system
    8.
    发明申请
    Expandable seal for use with medical device and system 失效
    用于医疗设备和系统的可扩展密封件

    公开(公告)号：US20050085885A1

    公开(公告)日：2005-04-21

    申请号：US10968305

    申请日：2004-10-20

    申请人： Aaron Janke ,  Larry Hum ,  Randy Westlund ,  Ronald Heil ,  Bruce Tockman

    发明人： Aaron Janke ,  Larry Hum ,  Randy Westlund ,  Ronald Heil ,  Bruce Tockman

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0573 ,  A61N1/0565

    摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.

    摘要翻译： 适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。 引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 引线可以包括用于将电极固定到心脏组织的固定螺旋。 导线组件可以替代地包括开放的管腔引线端头。 在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。 密封件包括可膨胀基质，例如水凝胶。 当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。 密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。 结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

    Distal or proximal fixation of over-the-tether myocardial leads
    9.
    发明申请
    Distal or proximal fixation of over-the-tether myocardial leads 有权
    远端或近端固定超过系绳心肌引线

    公开(公告)号：US20050137674A1

    公开(公告)日：2005-06-23

    申请号：US10972298

    申请日：2004-10-22

    申请人： M. Coe ,  Ronald Heil ,  Peter Kelley ,  Jason Shiroff ,  Randy Westlund ,  Donald Palme

    发明人： M. Coe ,  Ronald Heil ,  Peter Kelley ,  Jason Shiroff ,  Randy Westlund ,  Donald Palme

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587 ,  A61N2001/0578

    摘要： The present invention is a myocardial lead attachment system for securing a lead within the myocardium. The attachment system includes an anchor configured to engage the heart, a tether coupled to the anchor and a lead body. The lead body has a proximal end, a distal end, a lumen for accepting the tether and a lock housing in the lumen. A lock structure is on the tether and mates with the lock housing and restrains motion of the lead with respect to the tether in either of a proximal or a distal direction.

    摘要翻译： 本发明是用于将铅固定在心肌内的心肌引导附着系统。 附接系统包括构造成接合心脏的锚，连接到锚固体的系绳和引导体。 引线体具有近端，远端，用于接纳系绳的内腔和在内腔中的锁定壳体。 锁定结构位于系绳上并且与锁定壳体配合并且在近端或远端方向中抑制引线相对于系绳的运动。