公开(公告)号：US08202486B2

公开(公告)日：2012-06-19

申请号：US12843557

申请日：2010-07-26

申请人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

发明人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

IPC分类号： C12M1/36 ,  C12M1/34

CPC分类号： B01L3/502776 ,  B01L3/502738 ,  B01L3/502753 ,  B01L2200/0636 ,  B01L2400/0421 ,  G01N27/44717 ,  G01N27/44791 ,  G01N30/84 ,  Y10T137/0318 ,  Y10T137/877 ,  Y10T137/87788

摘要： The invention provides a device, system, and method for isolating one or more sample components of a sample material following separation of the sample material into a plurality of sample components. The device includes first and second pinching channels, a separation channel extending between the first and second pinching channels, a collection leg that includes a collection well, and a waste leg, all of which are in fluid communication with a switching region. In the method, a sample material is separated into a plurality of separated components in the device. and one or more of the separated components are isolated in the collection well. The separated components are constrained and elongated in the switching region by first and second buffer streams.

摘要翻译： 本发明提供一种用于在将样品材料分离成多个样品组分之后分离样品材料的一个或多个样品组分的装置，系统和方法。 该装置包括第一和第二夹持通道，在第一和第二夹持通道之间延伸的分离通道，包括收集井的收集支路和与切换区域流体连通的废料支路。 在该方法中，将样品材料分离成多个分离的部件。 并且一个或多个分离的组分在收集井中分离。 分离的组件在开关区域中受到第一和第二缓冲流的限制和拉长。

公开(公告)号：US20120222959A1

公开(公告)日：2012-09-06

申请号：US13471300

申请日：2012-05-14

申请人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

发明人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

IPC分类号： G01N27/447 ,  G01N33/559

CPC分类号： B01L3/502776 ,  B01L3/502738 ,  B01L3/502753 ,  B01L2200/0636 ,  B01L2400/0421 ,  G01N27/44717 ,  G01N27/44791 ,  G01N30/84 ,  Y10T137/0318 ,  Y10T137/877 ,  Y10T137/87788

摘要： The invention provides a device, system, and method for isolating one or more sample components of a sample material following separation of the sample material into a plurality of sample components. The device includes first and second pinching channels, a separation channel extending between the first and second pinching channels, a collection leg that includes a collection well between first and second ends of the collection leg, and a waste leg, all of which are in fluid communication with a switching region. In the method, a sample material is separated into a plurality of separated components in the device and one or more of the separated components are isolated in the collection well. The separated components are constrained and elongated in the switching region by first and second buffer streams.

摘要翻译： 本发明提供一种用于在将样品材料分离成多个样品组分之后分离样品材料的一个或多个样品组分的装置，系统和方法。 该装置包括第一和第二夹持通道，在第一和第二夹持通道之间延伸的分离通道，收集腿，其包括在收集腿的第一和第二端之间的收集井，以及废物腿，所有这些都处于流体 与切换区域的通信。 在该方法中，将样品材料分离成装置中的多个分离的组分，并将一个或多个分离的组分隔离在收集阱中。 分离的组件在开关区域中受到第一和第二缓冲流的限制和拉长。

公开(公告)号：US08277744B2

公开(公告)日：2012-10-02

申请号：US13471300

申请日：2012-05-14

申请人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

发明人： Josh Molho ,  Hui Xu ,  Jorge J. Zaninovich

IPC分类号： C12M1/36 ,  C12M1/34

CPC分类号： B01L3/502776 ,  B01L3/502738 ,  B01L3/502753 ,  B01L2200/0636 ,  B01L2400/0421 ,  G01N27/44717 ,  G01N27/44791 ,  G01N30/84 ,  Y10T137/0318 ,  Y10T137/877 ,  Y10T137/87788

摘要： The invention provides a device, system, and method for isolating one or more sample components of a sample material following separation of the sample material into a plurality of sample components. The device includes first and second pinching channels, a separation channel extending between the first and second pinching channels, a collection leg that includes a collection well between first and second ends of the collection leg, and a waste leg, all of which are in fluid communication with a switching region. In the method, a sample material is separated into a plurality of separated components in the device and one or more of the separated components are isolated in the collection well. The separated components are constrained and elongated in the switching region by first and second buffer streams.

摘要翻译： 本发明提供一种用于在将样品材料分离成多个样品组分之后分离样品材料的一个或多个样品组分的装置，系统和方法。 该装置包括第一和第二夹持通道，在第一和第二夹持通道之间延伸的分离通道，收集腿，其包括在收集腿的第一和第二端之间的收集井，以及废物腿，所有这些都处于流体 与切换区域的通信。 在该方法中，将样品材料分离成装置中的多个分离的组分，并将一个或多个分离的组分隔离在收集阱中。 分离的组件在开关区域中受到第一和第二缓冲流的限制和拉长。