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1.发明申请公开(公告)号：US20100106304A1
公开(公告)日：2010-04-29
申请号：US12605669
申请日：2009-10-26
CPC分类号： B60H1/0065
摘要： A control device of a blower and air conditioner module a for motor vehicle is disclosed with a blower controller and an air conditioner controller, which governs the refrigerating plant with a refrigerant condenser, as well as flaps and valves of the blower and air conditioner module, and processes information from sensors and a man-machine interface, with the blower controller and the air conditioner controller, together with a blower motor controller of a blower motor designed as a central control device and it is placed on the blower motor.
摘要翻译： 公开了一种用于机动车辆的鼓风机和空调模块a的控制装置，其具有用制冷剂冷凝器管理制冷设备的吹风机控制器和空调控制器以及鼓风机和空调模块的襟翼和阀， 并且与鼓风机控制器和空调控制器一起的传感器和人机界面的信息与设计为中央控制装置的鼓风机电动机的鼓风机电动机控制器一起处理，并且被放置在鼓风机电动机上。
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公开(公告)号：US20130187067A1
公开(公告)日：2013-07-25
申请号：US13812019
申请日：2011-07-25
申请人： Michael Weiss , Guido Mertens
发明人： Michael Weiss , Guido Mertens
IPC分类号： G01N21/59
CPC分类号： G01N21/59 , A61L2/081 , G01N21/05 , G01N2021/0367
摘要： An optical measuring system includes at least one radiation source, at least one radiation receiver, and at least one flow through cell. The radiation emitted by the at least one radiation source passes at least partially in an optical path between the radiation source and the radiation receiver through the flow through cell and then strikes the at least one radiation receiver. The radiation receiver is embodied to output a signal dependent on the intensity of the radiation striking the radiation receiver, wherein the flow through cell is arranged in a cell holder, which is connected via a first connection interface releasably with the radiation receiver and which is connected via a second connection interface releasably with the radiation source.
摘要翻译： 光学测量系统包括至少一个辐射源，至少一个辐射接收器和至少一个流通池。 由至少一个辐射源发射的辐射至少部分地在辐射源和辐射接收器之间的光路中穿过细胞通过，然后撞击至少一个辐射接收器。 辐射接收器被实现为输出取决于射入辐射接收器的辐射的强度的信号，其中流通池通过电池被布置在电池座中，电池座通过第一连接接口与放射线接收器可释放地连接并连接 经由可释放地与辐射源连接的第二连接接口。
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公开(公告)号：US20120316107A1
公开(公告)日：2012-12-13
申请号：US13472833
申请日：2012-05-16
申请人： Michael Weiss
发明人： Michael Weiss
摘要： A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue thereof connected by a polypeptide of 4-10 amino acids. The fibrillation-resistant insulin analogue preferably displays less than 1 percent fibrillation with incubation at 37° C. for at least 21 days. A single-chain insulin analogue displays greater in vitro insulin receptor binding than normal insulin while displaying less than or equal binding to IGFR than normal insulin. The fibrillation-resistant insulin may be used to treat a patient using an implantable or external insulin pump, due to its greater fibrillation resistance.
摘要翻译： 抗纤维化胰岛素类似物可以是单链胰岛素类似物或其生理上可接受的盐，其含有胰岛素A链序列或其类似物，以及通过4-10个氨基的多肽连接的胰岛素B链序列或其类似物 酸。 抗纤维化胰岛素类似物优选在37℃下孵育至少21天显示低于1％的纤颤。 单链胰岛素类似物显示比正常胰岛素更大的体外胰岛素受体结合，而与正常胰岛素显示小于或等于IGFR的结合。 抗纤维化胰岛素可以用于使用可植入或外用的胰岛素泵治疗患者，因为它具有更大的抗起伏性。
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公开(公告)号：US20120277148A1
公开(公告)日：2012-11-01
申请号：US13515192
申请日：2010-12-13
申请人： Michael Weiss
发明人： Michael Weiss
摘要： An insulin analogue comprises a B-chain polypeptide incorporating a chlorinated phenylalanine. The chlorinated phenylalanine may be located at position B24. The chlorinated phenylalanine may be para-monochloro-phenylalanine. The analogue may be of a mammalian insulin, such as human insulin. A nucleic acid encodes such an insulin analogue. The chlorinated insulin analogues retain significant activity. A method of treating a patient comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient. Chlorine substitution-based stabilization of insulin may reduce fibrillation and thereby enhance the treatment of diabetes mellitus in regions of the developing world lacking refrigeration.
摘要翻译： 胰岛素类似物包含掺入氯化苯丙氨酸的B链多肽。 氯代苯丙氨酸可以位于B24位。 氯化苯丙氨酸可以是对 - 一氯 - 苯丙氨酸。 类似物可以是哺乳动物胰岛素，例如人胰岛素。 核酸编码这样的胰岛素类似物。 氯化胰岛素类似物保留显着的活性。 治疗患者的方法包括向患者施用生理有效量的胰岛素类似物或其生理上可接受的盐。 基于氯取代的胰岛素稳定可能减少原纤维化，从而增强发展中国家缺乏制冷的地区的糖尿病治疗。
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公开(公告)号：US07987918B2
公开(公告)日：2011-08-02
申请号：US11351087
申请日：2006-02-09
IPC分类号： B25F5/02
CPC分类号： B25F5/02
摘要： An electric hand-held power tool has a housing, a double-shelled handle attached axially to the housing, a selector ring pivotably located in the housing, and an actuating element supported by the selector ring and swivelable manually. The housing and the handle have a line connecting domes oriented parallel to an axis of the housing and located in a parting plane region between the housing and the handle for receiving connecting units. The connecting domes include centering elements for guiding and exactly positioning the handle shells when the handle shells are attached individually to the housing.
摘要翻译： 电动手持式电动工具具有壳体，轴向安装于壳体的双壳手柄，可枢转地定位在壳体中的选择环，以及由选择环支撑并可手动旋转的致动元件。 壳体和手柄具有连接圆顶的线，平行于壳体的轴线定向并且位于壳体和手柄之间的分离平面区域中，用于接收连接单元。 连接圆顶包括定心元件，用于在把手壳单独地附接到壳体时引导和精确地定位手柄壳。
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公开(公告)号：US20100199936A1
公开(公告)日：2010-08-12
申请号：US12674496
申请日：2008-07-30
申请人： Michael Weiss , Rainer Ottersbach , Jochen Auchter , Rudolf Eydam
发明人： Michael Weiss , Rainer Ottersbach , Jochen Auchter , Rudolf Eydam
IPC分类号： F01L1/34
CPC分类号： F01L1/344 , F01L1/3442 , F01L2001/34483
摘要： A timing adjustment device with axially joined components, clamped by a camshaft central screw on a hub element which maintains the required peripheral position of these components relative to one another within a narrow tolerance range. On a disk element of the timing adjustment device an insert section is formed, which can be inserted into a recess formed in the hub element and, in the region of the insert section, at least one anchoring structure is formed, through which the insert section is anchored on a counter-structure, which is provided by the hub element.
摘要翻译： 一种具有轴向连接部件的定时调节装置，其由轮毂元件上的凸轮轴中心螺钉夹紧，所述轮毂元件在窄公差范围内保持这些部件相对于彼此的所需周边位置。 在定时调节装置的盘元件上，形成插入部分，该插入部分可插入到形成在轮毂元件中的凹部中，并且在插入部分的区域中形成至少一个锚固结构，插入部分 锚定在由轮毂元件提供的对抗结构上。
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公开(公告)号：US20090158723A1
公开(公告)日：2009-06-25
申请号：US12336956
申请日：2008-12-17
申请人： Ralf Riekers , Michael Weiss
发明人： Ralf Riekers , Michael Weiss
IPC分类号： F01N7/10
CPC分类号： F01N13/102 , F01N13/10 , F01N13/107 , F01N13/1827 , F01N13/1838 , F01N2450/24
摘要： The present invention relates to an exhaust manifold for an internal combustion engine, in particular in a motor vehicle, comprising a housing from which a plurality of inlet pipes emanate, which, in the built-in state, lead to cylinders of the internal combustion engine, and comprising a flange, which is welded to the inlet pipes and which, in the built-in state, is screwed to the cylinder head of the internal combustion engine by means of a screw connection. The fatigue strength of the exhaust manifold can be improved by subdividing the flange into at least two partial flanges in a longitudinal direction of the exhaust manifold.
摘要翻译： 本发明涉及一种用于内燃机，特别是机动车辆的排气歧管，其特征在于，包括一个外壳，多个入口管从该外壳排出，该外壳在内置状态下通向内燃机的气缸 并且包括法兰，其被焊接到入口管，并且在内置状态下，通过螺纹连接将其拧入内燃机的气缸盖。 可以通过将凸缘细分成排气歧管的纵向方向上的至少两个局部凸缘来提高排气歧管的疲劳强度。
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公开(公告)号：US07518281B2
公开(公告)日：2009-04-14
申请号：US10511286
申请日：2003-05-30
申请人： Winfried Habel , Otto Baumann , Siegfried Fehrle , Andre Ullrich , Michael Weiss , Hardy Schmid
发明人： Winfried Habel , Otto Baumann , Siegfried Fehrle , Andre Ullrich , Michael Weiss , Hardy Schmid
IPC分类号： H02K5/14
CPC分类号： H02K5/148 , H02K2205/06 , Y10T29/49009 , Y10T29/53143
摘要： An electric motor includes carbon brushes (5) disposed in a holder (6) that are pressed by means of a spring force (7) in a radial direction against a jacket face of a cylindrical collector (4) that is fixed to an armature shaft (2) of the motor. The holder (6) for the carbon brushes (5) can be removed from the motor with little effort as a result of a provision of covering means (11, 12) that cover a pivot bearing (3) of the armature shaft (2) to protect it against the entry of dirt on a side of the covering means (11, 12) facing the holder (6) for the carbon brushes (5), provided with one or more chamfers (14, 15) in such a way that the carbon brushes (5) slide over the covering means (11, 12) as the holder (6) is being pulled off and that the carbon brushes (5) thereby are thrust radially outward counter to the spring force (7).
摘要翻译： 电动机包括设置在保持器（6）中的碳刷（5），其通过弹簧力（7）沿径向压靠在圆柱形收集器（4）的护套面上，该圆柱形收集器（4）固定到电枢轴 （2）电机。 由于设置覆盖电枢轴（2）的枢轴承（3）的覆盖装置（11,12），用于碳刷（5）的保持器（6）可以很少地努力地从电动机中移除， 以防止在面向具有一个或多个倒角（14,15）的碳刷（5）的保持器（6）的覆盖装置（11,12）的一侧上的污物进入，以使得 当刷子（6）被拉出时，碳刷（5）在覆盖装置（11,12）上滑动，因此碳刷（5）相对于弹簧力（7）被径向向外推。
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公开(公告)号：US07397153B2
公开(公告)日：2008-07-08
申请号：US11195245
申请日：2005-08-02
申请人： Manfred Buck , Siegfried Fehrle , Uwe Engelfried , Michael Weiss
发明人： Manfred Buck , Siegfried Fehrle , Uwe Engelfried , Michael Weiss
IPC分类号： H02K7/14
CPC分类号： H01H9/063 , B25F5/001 , H01R39/415 , H02K23/18 , H02K23/66
摘要： A power tool has an electric motor, a brush element that is supported rotatably for switchover between clockwise operation and counterclockwise operation of the electric motor and includes a brush holder, and a switch unit, embodied separately from the brush element and connected in form-locking fashion to the brush element, which switch unit has an actuating element for actuation by a user, can be slipped in the axial direction onto the brush element, located on the electric motor, and is connected in the axial direction to the brush element.
摘要翻译： 电动工具具有电动马达，可旋转地支撑的电刷元件，用于在电动机的顺时针操作和逆时针操作之间进行切换，并且包括刷保持器和开关单元，其独立于刷元件并且以形状锁定 对于刷子元件，该开关单元具有用于由用户致动的致动元件，可以沿着轴向方向滑动到位于电动机上的刷元件上，并且在轴向方向上连接到刷元件。
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公开(公告)号：US07320991B2
公开(公告)日：2008-01-22
申请号：US10469359
申请日：2002-02-26
申请人： William D. Figg , Kurt Eger , Uwe Teubert , Michael Weiss , Michael Guetschow , Thomas Hecker , Sunna Hauschildt
发明人： William D. Figg , Kurt Eger , Uwe Teubert , Michael Weiss , Michael Guetschow , Thomas Hecker , Sunna Hauschildt
IPC分类号： A61K31/445
CPC分类号： C07D209/48 , A61K31/4035 , A61K31/454 , A61K31/506 , A61K31/513 , C07D401/04 , C07D403/04 , A61K2300/00
摘要： A number of thalidomide metabolites having superior anti-angiogenic properties have now been isolated and identified. In addition, thalidomide analogs that mimic the effects of the isolated and identified active thalidomide metabolites, and variations of such thalidomide analogs, have been developed. Such thalidomide analog compounds show enhanced potency in the inhibition of undesirable angiogenesis without the undesirable effects of administration of thalidomide.
摘要翻译： 已经分离和鉴定了许多具有优异抗血管生成特性的沙利度胺代谢物。 此外，已经开发了模拟分离和鉴定的活性沙利度胺代谢物的作用的沙利度胺类似物，以及这种沙利度胺类似物的变体。 这种沙利度胺类似物化合物在抑制不希望的血管发生中表现出增强的效力，而没有施用沙利度胺的不期望的作用。
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