摘要:
The invention provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
摘要:
A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
摘要:
A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
摘要翻译:一种生物可降解的透明质酸衍生物,其包含由式(HA) - [O(CO)NH-M] p H表示的改性透明质酸重复单元,其中HA是包含N-乙酰基-D- 葡萄糖胺和D-葡萄糖醛酸,M是含有C 2-16烃基或预聚物的改性部分,p是1至4的整数。当生物降解的透明质酸衍生物溶于 亲水介质可以形成胶束并且可以用于捕获药物活性或生物活性分子。
摘要:
The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
摘要:
The invention provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
摘要:
The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
摘要:
A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.
摘要:
A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.
摘要:
The present invention relates to a method for encapsulating a substrate, which comprises:(a1) providing a substrate with a plurality of chips mounted on a top side of the substrate;(b1) compressing a dry film photoresist on the top side of the substrate to form a photoresist layer;(c1) exposing the photoresist layer to a light source through a mask to form unexposed photoresist regions and exposed photoresist regions;(d1) developing the photoresist layer to uncover underlying portions of the unexposed photoresist regions;(e1) molding the top side of the substrate with a molding material;(f1) curing the molding material; and(g1) removing the unexposed photoresist regions from the substrate with a photoresist-removing agent.
摘要:
The present invention relates to a method for encapsulating a substrate, which comprises: (a1) providing a substrate with a plurality of chips mounted on a top of the substrate; (b1) compressing a dry film photoresist on the top side of the substrate to form a photoresist layer; (c1) exposing the photoresist layer to a light source through a mask to form unexposed photoresist regions and exposed photoresist regions; (d1) developing the photoresist layer to uncover underlying portions of the unexposed photoresist regions; (e1) molding the top side of the substrate with a molding material; (f1) curing the molding material; and (g1) removing the unexposed photoresist regions from the substrate with a photoresist-removing agent.