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公开(公告)号：US07790736B2
公开(公告)日：2010-09-07
申请号：US10918317
申请日：2004-08-12
申请人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , A61K31/506 , A61P19/02
CPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
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公开(公告)号：US20110087022A1
公开(公告)日：2011-04-14
申请号：US12964410
申请日：2010-12-09
IPC分类号： C07D513/04 , C07D487/04 , C07D498/02
CPC分类号： C07D471/04 , C07D487/04 , C07D513/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a member selected from the group consisting of: wherein E is CH or N, Q is selected from the group consisting of CO, CS, SO, SO2, or C═NR4, and L, X, Z, R2 and R3 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含选自以下的成员：其中E是CH或N，Q选自CO，CS，SO ，SO 2或C≡NR4，并且L，X，Z，R 2和R 3如本文所定义。
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公开(公告)号：US07723344B2
公开(公告)日：2010-05-25
申请号：US10918327
申请日：2004-08-12
申请人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D239/47 , C07D239/48 , C07D403/12 , A61K31/505
CPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
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公开(公告)号：US07470700B2
公开(公告)日：2008-12-30
申请号：US10917955
申请日：2004-08-12
申请人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney, II , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D239/47 , C07D239/48 , C07D403/12 , A61K31/505 , A61K31/506 , A61P19/02
CPC分类号： C07D239/36 , C07D239/47 , C07D239/52 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/06 , C07D409/14 , C07D417/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于包含式I的DPP-IV抑制剂：其中取代基如本文所述。
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公开(公告)号：US07872124B2
公开(公告)日：2011-01-18
申请号：US11305818
申请日：2005-12-16
IPC分类号： C07D239/70
CPC分类号： C07D471/04 , C07D487/04 , C07D513/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a member selected from the group consisting of: wherein E is CH or N, Q is selected from the group consisting of CO, CS, SO, SO2, or C═NR4, and L, X, Z, R2 and R3 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含选自以下的成员：其中E是CH或N，Q选自CO，CS，SO ，SO 2或C≡NR4，并且L，X，Z，R 2和R 3如本文所定义。
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公开(公告)号：US08093382B2
公开(公告)日：2012-01-10
申请号：US12964410
申请日：2010-12-09
IPC分类号： C07D513/04
CPC分类号： C07D471/04 , C07D487/04 , C07D513/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a member selected from the group consisting of: wherein E is CH or N, Q is selected from the group consisting of CO, CS, SO, SO2, or C═NR4, and L, X, Z, R2 and R3 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含选自以下的成员：其中E是CH或N，Q选自CO，CS，SO ，SO 2或C≡NR4，并且L，X，Z，R 2和R 3如本文所定义。
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公开(公告)号：US07550590B2
公开(公告)日：2009-06-23
申请号：US10809635
申请日：2004-03-24
申请人： Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D285/16 , A61K31/5395
CPC分类号： C07D471/04 , C07D401/04 , C07D403/04 , C07D473/18 , C07D487/04
摘要： Compounds, pharmaceuticals, kits, and methods are provided for use with DPP-IV and other S9 protease that comprise a compound comprising the formula: wherein Q is selected from the group of CO, SO, SO2, or C═NR9; and R1, R2, R3 and R4 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含下式的化合物：其中Q选自CO，SO，SO 2或C-NR 9; 并且R 1，R 2，R 3和R 4如本文所定义。
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公开(公告)号：US07790734B2
公开(公告)日：2010-09-07
申请号：US10934326
申请日：2004-09-02
申请人： Sheldon X. Cao , Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
发明人： Sheldon X. Cao , Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
IPC分类号： C07D239/47 , C07D239/48 , C07D403/12 , A61K31/505
CPC分类号： C07D401/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于包含式I的DPP-IV抑制剂：其中取代基如本文所述。
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公开(公告)号：US07687625B2
公开(公告)日：2010-03-30
申请号：US10809637
申请日：2004-03-24
申请人： Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney , Stephen W. Kaldor , Jeffrey A. Stafford , Michael B. Wallace , Zhiyuan Zhang
IPC分类号： C07D285/16 , A61K31/5395
CPC分类号： C07D471/04 , C07D401/04 , C07D403/04 , C07D473/18 , C07D487/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 protease that comprise a compound comprising the formula: wherein Q is selected from the group of CO, SO, SO2, or C═NR9; and R1, R2, R3 and R4 are as defined herein.
摘要翻译： 提供化合物，药物，试剂盒和方法用于DPP-IV和其它包含下式的化合物的S9蛋白酶：其中Q选自CO，SO，SO 2或C = NR 9; 并且R 1，R 2，R 3和R 4如本文所定义。
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公开(公告)号：US07638638B2
公开(公告)日：2009-12-29
申请号：US10846348
申请日：2004-05-13
申请人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
发明人： Jun Feng , Stephen L. Gwaltney , Jeffrey A. Stafford , Michael B. Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
IPC分类号： C07D295/02 , A61K31/40
CPC分类号： C07K5/06026 , C07D207/16 , C07D277/04 , C07D401/12 , C07K5/06043
摘要： Pharmaceuticals, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound with the formula: where the labeled substituents are as described herein.
摘要翻译： 提供药物，试剂盒和方法用于DPP-IV和其它S9蛋白酶，其包含下式的化合物：其中标记的取代基如本文所述。
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