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1.发明授权Transdermal patch having a pressure-sensitive adhesive comprising (meth)acrylic acid alkyl ester, N-hydroxyalkyl(meth)acrylamide, and vinyl monomers 有权具有包含（甲基）丙烯酸烷基酯，N-羟烷基（甲基）丙烯酰胺和乙烯基单体的压敏粘合剂的透皮贴剂公开(公告)号：US08361493B2
公开(公告)日：2013-01-29
申请号：US12945198
申请日：2010-11-12
申请人： Jun Ishikura , Raito Funayama , Yu Tachikawa , Junichi Sekiya , Tsuyoshi Kasahara , Ryo Hashino , Satoshi Ameyama , Hidetoshi Kuroda
发明人： Jun Ishikura , Raito Funayama , Yu Tachikawa , Junichi Sekiya , Tsuyoshi Kasahara , Ryo Hashino , Satoshi Ameyama , Hidetoshi Kuroda
CPC分类号： A61L15/585 , C09J133/26 , Y10T428/2887 , Y10T428/2891
摘要： The patch according to an embodiment of the present invention includes: a support; and a pressure-sensitive adhesive layer on at least one surface of the support, wherein: the pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N-hydroxyalkyl(meth)acrylamide; a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 wt % to 90 wt % and a content of the N-hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 1 wt % to 20 wt %; and the monomer components are substantially free of a monomer having a carboxyl group.
摘要翻译： 根据本发明的实施例的贴片包括：支撑件; 和压敏粘合剂层，其中：所述压敏粘合剂层含有丙烯酸共聚物，所述丙烯酸共聚物通过共聚含有（a）至少一种（甲基）丙烯酸单体的单体成分而得到的丙烯酸共聚物 酸性烷基酯和（b）至少一种N-羟烷基（甲基）丙烯酰胺的单体; 相对于单体成分的总量，（甲基）丙烯酸烷基酯单体（a）的含量为50重量％〜90重量％，N-羟烷基（甲基）丙烯酰胺单体（b）的含量与 相对于总量为1重量％〜20重量％ 并且单体组分基本上不含具有羧基的单体。
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公开(公告)号：US20120225110A1
公开(公告)日：2012-09-06
申请号：US13399384
申请日：2012-02-17
申请人： Ryo Hashino , Hidetoshi Kuroda , Satoshi Ameyama , Shiro Satoda , Jun Ishikura
发明人： Ryo Hashino , Hidetoshi Kuroda , Satoshi Ameyama , Shiro Satoda , Jun Ishikura
CPC分类号： A61L15/58 , A61K9/7061 , A61L15/44 , Y10T428/2887 , Y10T428/2891 , C08L33/10
摘要： A patch according to an embodiment of the present invention includes a support and a pressure-sensitive adhesive layer provided on at least one surface of the support. The pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing a monomer mixture containing (a) a (meth)acrylic acid alkyl ester, (b) a hydroxyl group-containing monomer, and (c) a diketone group-containing monomer.
摘要翻译： 根据本发明的实施方式的贴片包括支撑体和设置在支撑体的至少一个表面上的压敏粘合剂层。 压敏粘合剂层含有通过共聚含有（a）（甲基）丙烯酸烷基酯，（b）含羟基单体和（c）含二酮基团的单体）的单体混合物而获得的丙烯酸共聚物。
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公开(公告)号：US20100260826A1
公开(公告)日：2010-10-14
申请号：US12662253
申请日：2010-04-07
申请人： Miki Makabe , Tsuyoshi Kasahara , Atsushi Hamada , Jun Ishikura
发明人： Miki Makabe , Tsuyoshi Kasahara , Atsushi Hamada , Jun Ishikura
CPC分类号： A61L15/44 , A61K9/7053 , A61L15/585 , A61L2300/606
摘要： Provided are a patch and a patch preparation having an adhesive layer on at least one surface of a support, and particularly, a patch and a patch preparation superior in skin adhesive force, and causing less adhesive residue on the skin surface. A patch having a support and an adhesive layer formed on at least one surface of the support, wherein the adhesive layer is obtained by crosslinking a first polymer having a butadiene skeleton portion and a second polymer different from the first polymer in the presence of an organic peroxide.
摘要翻译： 本发明提供一种贴片和贴片制剂，其在支持体的至少一个表面上具有粘合剂层，特别是在皮肤粘合力方面优异的贴剂和贴剂，并且在皮肤表面上引起较少的粘合剂残留。 具有支撑体和形成在支撑体的至少一个表面上的粘合层的贴剂，其中所述粘合剂层通过在有机物存在下交联具有丁二烯骨架部分的第一聚合物和不同于第一聚合物的第二聚合物而获得 过氧化物。
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公开(公告)号：US20080311178A1
公开(公告)日：2008-12-18
申请号：US12155449
申请日：2008-06-04
CPC分类号： C08K5/0016 , A61K9/7007 , C08K5/101 , C08L13/00 , C08L19/006
摘要： The present invention provides a composition for a medical material or a hygiene material, which contains a large amount of an organic liquid component, has sufficient flexibility and can retain shape. The present invention provides a gel composition for a medical material or a hygiene material, which contains a liquid rubber component having a functional group capable of crosslinking reaction in a molecule and 90 parts by weight or above and 1250 parts by weight or below of an organic liquid component relative to 100 parts by weight of the rubber component, which gel composition is crosslinked.
摘要翻译： 本发明提供一种含有大量有机液体成分的医疗用材料或卫生材料用组合物，具有充分的柔软性，能够保持形状。 本发明提供了一种医用材料或卫生材料用凝胶组合物，其含有具有能够在分子中交联反应的官能团的液态橡胶成分和90重量份以上且1250重量份以下的有机物 相对于100重量份的橡胶组分，该凝胶组合物是交联的。
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公开(公告)号：US20100255071A1
公开(公告)日：2010-10-07
申请号：US12662223
申请日：2010-04-06
申请人： Miki Makabe , Tsuyoshi Kasahara , Atsushi Hamada , Jun Ishikura
发明人： Miki Makabe , Tsuyoshi Kasahara , Atsushi Hamada , Jun Ishikura
IPC分类号： A61K9/70 , A61K31/405 , A61P17/02 , A61F13/02
CPC分类号： A61L15/58 , A61K9/7053 , C08L23/20
摘要： Provided are a patch and a patch preparation having an adhesive layer on at least one surface of a support, and particularly, a patch and a patch preparation superior in skin adhesive force, and causing less adhesive residue on the skin surface. A patch having a support and an adhesive layer formed on at least one surface of the support, wherein the adhesive layer contains an elastomer obtained by crosslinking a polymer having a butadiene skeleton in the presence of an organic peroxide, and the ratio of the weight of a toluene-insoluble component in the adhesive layer to the total weight of the adhesive layer is 5-32 wt %.
摘要翻译： 本发明提供一种贴片和贴片制剂，其在支持体的至少一个表面上具有粘合剂层，特别是在皮肤粘合力方面优异的贴剂和贴剂，并且在皮肤表面上引起较少的粘合剂残留。 一种具有支撑体的粘合剂层和形成在载体的至少一个表面上的粘合剂层，其中粘合剂层含有通过在有机过氧化物的存在下交联具有丁二烯骨架的聚合物而获得的弹性体， 粘合剂层中的甲苯不溶性成分相对于粘合剂层的总重量为5-32重量％。
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6.发明申请Gel composition for medical material or hygiene material, molded article thereof and adhesive material or adhesive preparation using same 审中-公开用于医疗材料或卫生材料的凝胶组合物，其模制品和粘合剂材料或使用其的粘合剂制剂公开(公告)号：US20100144901A1
公开(公告)日：2010-06-10
申请号：US12453909
申请日：2009-05-27
CPC分类号： A61Q19/00 , A61K8/042 , A61K8/72 , A61K9/7038 , A61L15/30 , A61L15/60 , C08K5/0016 , C08K5/101 , C08K5/1515 , C08L13/00 , C08L19/006 , C08L9/10
摘要： The present invention can provide a composition for a medical material or a hygiene material, which can retain a considerable amount of a chemical substance such as a drug and the like or an organic liquid component, is associated with less limitation on molding, does not easily drop off when adhered to the skin, provides a better feeling during adhesion to the skin, produces decreased adhesive residue when detached from the skin, and shows good followability to the skin. The present invention provides a gel composition obtained by crosslinking a composition for gel preparation comprising a liquid rubber having a crosslinkable functional group in a molecule and 34.6-64.6 wt % of an organic liquid component relative to the total weight of the composition for gel preparation.
摘要翻译： 本发明可以提供可以保持大量化学物质如药物等或有机液体成分的用于医疗材料或卫生材料的组合物与较少的模制限制相关联，不容易 粘附于皮肤时脱落，在与皮肤粘合时提供更好的感觉，与皮肤分离时会产生较少的粘合剂残留，并且对皮肤表现出良好的追随性。 本发明提供一种凝胶组合物，其通过将用于凝胶制剂的组合物交联，所述组合物包含分子中具有交联性官能团的液体橡胶和相对于凝胶制剂用组合物总重量为34.6-64.6重量％的有机液体组分。
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公开(公告)号：US20100068248A1
公开(公告)日：2010-03-18
申请号：US12585315
申请日：2009-09-11
IPC分类号： A61K9/70
CPC分类号： A61L15/585 , C08L21/00
摘要： The present invention provides a patch containing a support and an adhesive layer formed on at least one surface of the support, wherein the adhesive layer has a gel fraction of 50 wt %-75 wt %, and is comprised of a composition containing 33 wt %-65 wt % of a liquid rubber having a crosslinkable functional group in a molecule, which has an adhesive layer with a thickness sufficient for protection of a skin lesion and a wounded surface, which is flexible, adheres well to the skin, provides good feeling during adhesion, leaves less adhesive residue when removed from the skin, and shows good followability to skin deformation, as well as a patch preparation capable of sufficiently retaining a medicament and the like.
摘要翻译： 本发明提供了一种补片，其包含形成在支撑体的至少一个表面上的支撑体和粘合剂层，其中粘合剂层具有50重量％-75重量％的凝胶分数，并且由含有33重量％ -65重量％的分子中具有可交联官能团的液体橡胶，其具有足以保护皮肤损伤的厚度的粘合剂层和具有柔性的，适合于皮肤的受伤表面，具有良好的感觉 在粘合时，从皮肤上除去粘合剂残留物，并且对皮肤变形显示良好的追随性，以及能够充分保持药物等的贴片制剂。
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公开(公告)号：US20100015209A1
公开(公告)日：2010-01-21
申请号：US12458626
申请日：2009-07-17
CPC分类号： A61L15/58 , Y10T428/2852
摘要： Provided is a patch having good adhesion property, which stably maintains the quality for a long time.A patch containing a support and an adhesive layer formed on at least one surface of the support, wherein the adhesive layer contains an elastomer having a structure of the formula I: wherein P1 and P2 are each independently hydrogen, a hydroxy group or an organic group.
摘要翻译： 提供具有良好粘附性的贴剂，其长期稳定地保持质量。 一种在载体的至少一个表面上形成有载体和粘合层的贴剂，其中所述粘合剂层含有具有式I结构的弹性体：其中P1和P2各自独立地为氢，羟基或有机基团 。
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公开(公告)号：US20090028928A1
公开(公告)日：2009-01-29
申请号：US12216366
申请日：2008-07-02
CPC分类号： A61K9/7053 , A61L31/041 , Y10T428/2883 , C08L21/00
摘要： The present invention aims to provide a patch and a patch preparation that do not require an acrylic polymer, and are capable of maintaining a large amount of an organic liquid component in an adhesive layer.The present invention provides a patch containing a support and an adhesive layer provided on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber component other than polyisobutylene and solid at 25° C., a liquid rubber component having a crosslinkable functional group in a molecule, and an organic liquid component, the adhesive layer is crosslinked, and the liquid rubber component is contained in a proportion of less than 30 wt % relative to the total weight of the synthetic rubber component solid at 25° C. and the liquid rubber component.
摘要翻译： 本发明的目的在于提供一种不需要丙烯酸类聚合物并且能够在粘合剂层中保持大量有机液体成分的贴剂和贴片制剂。 本发明提供一种包含载体和粘合剂层的贴片，所述粘合剂层设置在所述载体的至少一个表面上，其中所述粘合层在25℃下包含除聚异丁烯和固体以外的合成橡胶组分，具有可交联的液体橡胶组分 分子中的官能团和有机液体组分，粘合剂层交联，并且液体橡胶组分的含量相对于合成橡胶组分固体在25℃下的总重量小于30重量％。 和液体橡胶组分。
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公开(公告)号：US08790690B2
公开(公告)日：2014-07-29
申请号：US12458627
申请日：2009-07-17
摘要： A patch containing a support and an adhesive layer formed on at least one surface of the support, wherein the adhesive layer contains an elastomer obtained by crosslinking a polymer having a butadiene skeleton in the presence of organic peroxide, wherein the patch has good adhesion property and maintain this quality for a long time.
摘要翻译： 一种在载体的至少一个表面上形成有支持体和粘合层的贴片，其中，所述粘合剂层含有通过在有机过氧化物的存在下交联具有丁二烯骨架的聚合物而获得的弹性体，其中所述贴片具有良好的粘合性， 保持这种质量很长一段时间。
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