公开(公告)号：US09988348B1

公开(公告)日：2018-06-05

申请号：US15615765

申请日：2017-06-06

Applicant: KING SAUD UNIVERSITY

Inventor： Yahia Nasser Mabkhot Gabr ,  Jamal Mohammed Ali Khaled ,  Mujeeb Abdullah Saeed Sultan ,  Salim S. Al-Showiman ,  Naiyf Sultan Helial Alaloi Alharbi ,  Hazem Ahmed Ghabbour

IPC: C07C329/00 ,  A61K31/265

CPC classification number: C07C329/00 ,  A61K31/265 ,  A61K2121/00

Abstract: A method for preparing a trithiocarbonate derivative compound includes reacting ethyl cyanoacetate, carbon disulfide (CS2) and ethyl chloroacetate in the presence of potassium carbonate (K2CO3) in an organic solvent to produce 2,2′-(thiocarbonylbis(sulfanediyl))diacetate compound, represented by the structural formula:

公开(公告)号：US12121504B1

公开(公告)日：2024-10-22

申请号：US18611026

申请日：2024-03-20

Applicant: KING SAUD UNIVERSITY

Inventor： Jamal Mohammed Ali Khaled ,  Naiyf Sultan Helial Alaloi Alharbi ,  Ramzi Ahmed Abdullah Mothana ,  Shine Moosa Kadaikunnan ,  Ahmed Saad Alobaidi

IPC: A61K31/231 ,  A61P31/10 ,  B01D15/42 ,  C11B1/10 ,  C12P7/6427

CPC classification number: A61K31/231 ,  A61P31/10 ,  B01D15/426 ,  C11B1/10 ,  C12P7/6427 ,  A61K2236/35

Abstract: A method of using a truffle-derived biomass for producing 1,3-diolein includes obtaining a mycelial biomass from truffles, preparing an extract from the mycelial biomass, and isolating the 1,3-diolein from the extract. In an embodiment, isolating the 1,3-diolein from the extract can include using column chromatography for eluting a portion of a first extract with a mixture including chloroform and methanol into a plurality of fractions, and using column chromatography for eluting at least one of the fractions with methanol to provide 1,3-diolein.

公开(公告)号：US10071960B1

公开(公告)日：2018-09-11

申请号：US15726263

申请日：2017-10-05

Applicant: KING SAUD UNIVERSITY

Inventor： Yahia Nasser Mabkhot ,  Jamal Mohammed Ali Khaled ,  Mujeeb Abdullah Sultan ,  Fahd Ali Nasr Mohammed ,  Naiyf Sultan Helial Alaloi Alharbi ,  Salim Showiman Al-Showiman ,  Hazem Ahmed Ghabbour

IPC: C07C329/06

CPC classification number: C07C329/06 ,  C07C329/00

Abstract: The present subject matter is directed to an enaminone-grafted trithiocarbonate compound having the structure: and the anticancer and antimicrobial activities exhibited by the compound.

公开(公告)号：US11806790B2

公开(公告)日：2023-11-07

申请号：US16716449

申请日：2019-12-16

Applicant: KING SAUD UNIVERSITY

Inventor： Naiyf Sultan Helial Alaloi Alharbi ,  Jamal Mohammed Ali Khaled ,  Mohamed Salah El-Din Hodhud ,  Shine Moosa Kadaikunnan ,  Ahmed Saad Alobaidi

IPC: A01N59/20 ,  A01N25/12 ,  B22F1/054 ,  B82Y40/00 ,  B22F9/24 ,  C12P3/00 ,  C01G3/10 ,  A01N63/30

CPC classification number: B22F9/24 ,  A01N25/12 ,  A01N59/20 ,  B22F1/054 ,  C01G3/10 ,  C12P3/00 ,  B82Y40/00 ,  C01P2002/01 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2002/84 ,  C01P2004/64 ,  A01N59/02 ,  A01N25/12 ,  A01N63/30

Abstract: A method of preparing metal nanoparticles using a fungal extract includes providing an aqueous solution including a metal salt; and combining the fungal extract with the aqueous metal salt solution to produce the metal nanoparticles. The fungal extract can be an aqueous extract of the manglicolous fungi The metal salt can be copper sulfate (CuSO4) and the metal nanoparticles can be copper nanoparticles. The metal nanoparticles can have a mean diameter in the range of from about 5 nm to about 100 nm. The copper nanoparticles can be used as an antimicrobial agent.

公开(公告)号：US10590438B1

公开(公告)日：2020-03-17

申请号：US16423532

申请日：2019-05-28

Applicant: KING SAUD UNIVERSITY

Inventor： Naiyf Sultan Helial Alaloi Alharbi ,  Jamal Mohammed Ali Khaled ,  Mohamed Salah El-Din Hodhod ,  Shine Moosa Kadaikunnan ,  Ahmed Saad Alobaidi

IPC: C12P3/00 ,  A01N59/20 ,  A01N25/12 ,  C01G3/10 ,  B82Y40/00

Abstract: A method of preparing metal nanoparticles using a fungal extract includes providing an aqueous solution including a metal salt; and combining the fungal extract with the aqueous metal salt solution to produce the metal nanoparticles. The fungal extract can be an aqueous extract of the manglicolous fungi The metal salt can be copper sulfate (CuSO4) and the metal nanoparticles can be copper nanoparticles. The metal nanoparticles can have a mean diameter in the range of from about 5 nm to about 100 nm. The copper nanoparticles can be used as an antimicrobial agent.