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公开(公告)号：US11337619B2
公开(公告)日：2022-05-24
申请号：US16319966
申请日：2017-08-02
发明人： Willem Potze , Petrus Carolus Maria Frissen , Aditya Mehendale , Jacek Lukasz Kustra , Peter Prinsen , Guillaume Leopold Theodorus Frederik Hautvast
摘要： A device (10) configured to detect the presence of metal artifacts in a patient's eye includes a head mount (14) configured to receive at least a portion of the patient's head. At least one inductor coil (12) is disposed on or in the head mount and positioned to inductively couple with at least one eye of the patient's head received into the head mount. An inductance meter (18) is operably connected to the at least one inductor coil to measure an inductance as a change of frequency of the at least one inductor coil. A processor (22) is programmed to: determine whether the inductance is greater than an inductance threshold value; and generate an indication of at least one metal artifact when the inductance is greater than the inductance threshold value. A display component (24) is configured to display the indication.
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公开(公告)号：US20180153619A1
公开(公告)日：2018-06-07
申请号：US15572840
申请日：2016-06-10
IPC分类号： A61B34/10 , A61N5/10 , A61B18/02 , A61B18/12 , A61B18/20 , A61N7/02 , A61B8/08 , A61B10/04 , G16H20/10
摘要： It is an object of the invention to improve treatment planning. This object is achieved by a dose planning system comprising a biopsy map creation module configured for receiving biopsy information for an organ of interest regarding biopsy locations and tissue characteristics of tissue found at the biopsy locations, wherein the biopsy map creation module is further configured for creating a spatially annotated biopsy map for the organ, by linking the spatial information on the biopsy locations to the tissue characteristics of tissue found at the corresponding biopsy locations. The dose planning system further comprises a probability map calculation module configured for creating a tumour probability map by calculating a tumour probability for locations in the organ from which no biopsy was taken by using the tumour and/or tissue characteristics from the biopsy locations and a dose planning module configured for creating a dose plan based on the tumour probability map, wherein planning constraints are such that on average a higher tumour probability results in a higher planned dose and a lower tumour probability results in a lower planned dose.
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公开(公告)号：US11423553B2
公开(公告)日：2022-08-23
申请号：US16763124
申请日：2018-11-05
摘要： The invention relates to a system and method for tracking at least one anatomic structure by means of an image-registration based tracking procedure using at least one parameter, where the anatomic structure includes a plurality of implanted markers. A parameter setting (6, 7) unit is configured to determine measured positions of the implanted markers in each image of a series of images acquired using an imaging unit (1), and to perform an optimization procedure to determine an optimized value of the at least one parameter on the basis of deviations between the measured and calculated positions. Then, the position of the anatomic structure is tracked in further images by means of the tracking procedure using the optimized value of the at least one parameter.
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公开(公告)号：US20200219627A1
公开(公告)日：2020-07-09
申请号：US16648797
申请日：2018-09-18
发明人： Sergio Consoli , Monique Hendriks , Pieter Christiaan Vos , Jacek Lukasz Kustra , Ralf Dieter Hoffmann , Dimitrios Mavroeidis
摘要： A method of clustering or grouping subjects that are similar to one another. A dataset contains, for each subject, a set of quantitative values which each represent a respective clinical or pathological feature of that subject. A principle component analysis, PCA, is performed on the dataset. Loadings of one of the first two principle components identified by the PCA are used to generate a respective dataset of weighting values. These weighting values are used to weigh or modify each set of quantitative values in the dataset. A clustering algorithm is performed on the weighted sets of subject data. The process may be iterated until user-defined stopping conditions are satisfied.
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公开(公告)号：US20200176130A1
公开(公告)日：2020-06-04
申请号：US16615165
申请日：2018-05-16
发明人： Jacek Lukasz Kustra , Monique Hendriks , Pieter Christiaan Vos , Sergio Consoli , Dimitrios Mavroeidis , Arlette van Wissen , Aart Tijmen van Halteren
摘要： There is provided an apparatus and a method of operating the apparatus for providing feedback to a participant directing a communication to one or more other participants. The apparatus (100) comprises a processor (102) configured to acquire, from one or more physiological characteristic sensors (104), one or more physiological characteristic signals from at least one participant to which the communication is directed as the communication is received by the at least one participant. The processor (102) is also configured to determine a measure of the quality of the communication based on a comparison of the one or more physiological characteristic signals acquired from the at least one participant with one or more expected physiological characteristic signals and control a user interface (108) to provide feedback of the determined quality measure of the communication to the participant directing the communication to the at least one participant.
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公开(公告)号：US11410780B2
公开(公告)日：2022-08-09
申请号：US16615165
申请日：2018-05-16
发明人： Jacek Lukasz Kustra , Monique Hendriks , Pieter Christiaan Vos , Sergio Consoli , Dimitrios Mavroeidis , Arlette van Wissen , Aart Tijmen van Halteren
摘要： There is provided an apparatus and a method of operating the apparatus for providing feedback to a participant directing a communication to one or more other participants. The apparatus (100) comprises a processor (102) configured to acquire, from one or more physiological characteristic sensors (104), one or more physiological characteristic signals from at least one participant to which the communication is directed as the communication is received by the at least one participant. The processor (102) is also configured to determine a measure of the quality of the communication based on a comparison of the one or more physiological characteristic signals acquired from the at least one participant with one or more expected physiological characteristic signals and control a user interface (108) to provide feedback of the determined quality measure of the communication to the participant directing the communication to the at least one participant.
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公开(公告)号：US20200251224A1
公开(公告)日：2020-08-06
申请号：US16648719
申请日：2018-09-10
发明人： Dimitrios Mavroeidis , Monique Hendriks , Pieter Christiaan Vos , Sergio Consoli , Jacek Lukasz Kustra , Johan Janssen , Ralf Dieter Hoffmann
摘要： The invention provides a method for evaluating a set of input data, the input data comprising at least one of: clinical data of a subject; genomic data of a subject; clinical data of a plurality of subjects; and genomic data of a plurality of subjects, using a deep learning algorithm. The method includes obtaining a set of input data, wherein the set of input data comprises raw data arranged into a plurality of data clusters and tuning the deep learning algorithm based on the plurality of data clusters. The deep learning algorithm comprises: an input layer; an output layer; and a plurality of hidden layers. The method further includes performing stabstical clustering on the raw data using the deep learning algorithm, thereby generating statistical clusters and obtaining a marker from each statistical cluster. Finally, the set of input data is evaluated based on the markers to derive data of medical relevance in respect of the subject or subjects.
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公开(公告)号：US20180140869A1
公开(公告)日：2018-05-24
申请号：US15571938
申请日：2016-05-30
发明人： Petrus Carolus Maria Frissen , Willem Potze , Aditya Mehendale , Jacek Lukasz Kustra , Peter Prinsen , Andreas Goedicke
IPC分类号： A61N5/10
CPC分类号： A61N5/1027 , A61B2090/3958 , A61N5/1007 , A61N5/1049 , A61N2005/1024 , A61N2005/1051
摘要： The invention relates to a device for determining positions of objects (1i) positioned in a measurement area, wherein the objects (1i) are capable of at least temporarily generating a magnetic field. The device comprises magnetometers (3i) arranged at a plurality of locations in a vicinity of the measurement area for locally measuring the magnetic field generated by the objects (1i), and an evaluation unit (5) coupled to the magnetometers (3i), the evaluation unit (5) being configured to determine the positions of the objects (1i) on the basis of the magnetic field measurements by the magnetometers (3i). The objects (1i) may be included in a human or animal body and may particularly be brachytherapy seeds.
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公开(公告)号：US11842268B2
公开(公告)日：2023-12-12
申请号：US16648719
申请日：2018-09-10
发明人： Dimitrios Mavroeidis , Monique Hendriks , Pieter Christiaan Vos , Sergio Consoli , Jacek Lukasz Kustra , Johan Janssen , Ralf Dieter Hoffmann
IPC分类号： G06N3/08 , G16H10/60 , G16H50/70 , G06N20/00 , G06F17/18 , G06F18/214 , G06F18/23213
CPC分类号： G06N3/08 , G06F17/18 , G06F18/214 , G06F18/23213 , G06N20/00 , G16H10/60 , G16H50/70
摘要： The invention provides a method for evaluating a set of input data, the input data comprising at least one of: clinical data of a subject; genomic data of a subject; clinical data of a plurality of subjects; and genomic data of a plurality of subjects, using a deep learning algorithm. The method includes obtaining a set of input data, wherein the set of input data comprises raw data arranged into a plurality of data clusters and tuning the deep learning algorithm based on the plurality of data clusters. The deep learning algorithm comprises: an input layer; an output layer; and a plurality of hidden layers. The method further includes performing statistical clustering on the raw data using the deep learning algorithm, thereby generating statistical clusters and obtaining a marker from each statistical cluster. Finally, the set of input data is evaluated based on the markers to derive data of medical relevance in respect of the subject or subjects.
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公开(公告)号：US20190336110A1
公开(公告)日：2019-11-07
申请号：US16349447
申请日：2017-11-24
发明人： Jacek Lukasz Kustra , Edmond van Dijk , Guillaume Leopold Theodorus Frederik Hautvast , Dave Senden , Dirk Binnekamp
摘要： The present invention relates to an ultrasound imaging system (100) for producing spatially compounded 3D ultrasound image data, comprising: —an ultrasound acquisition unit (16) for acquiring a plurality of 3D ultrasound image data having different but at least partially overlapping field of views, —a tracking unit (62) adapted to determine a relative spatial position of each of 5 the plurality of 3D ultrasound image data with respect to each other, and —a stitching unit (64) adapted to compound the plurality of 3D ultrasound image data by stitching them to each other in order to generate compounded 3D ultrasound image data, wherein the stitching unit (64) is adapted to calculate a stitching order of the plurality of 3D ultrasound image data based on the determined relative spatial position of the 3D 10 ultrasound image data by minimizing an overlapping area of the different field of views of the plurality of 3D ultrasound image data, and wherein stitching unit (64) is adapted to stitch the plurality of 3D ultrasound image data according to said stitching order.
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