公开(公告)号：US20150141733A1

公开(公告)日：2015-05-21

申请号：US14600474

申请日：2015-01-20

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Prashant KUMAR ,  Karl Antonin BZDUSEK ,  Vaitheeswaran RANGANATHAN ,  Matthew PALMER ,  Michael KANTOR

IPC: A61N5/10

CPC classification number: A61N5/1039 ,  A61N5/1031 ,  A61N5/1038 ,  A61N5/1042 ,  A61N5/1045 ,  A61N5/1047 ,  G06F19/3481 ,  G16H20/40

Abstract: A therapy planning system and method generate an optimal treatment plan accounting for changes in anatomy. Therapy is delivered to the subject according to a first auto-planned optimal treatment plan based on a first image of a subject. A second image of the subject is received after a period of time. The second image is registered with the first image to generate a deformation map accounting for physiological changes. The second image is segmented into regions of interest using the deformation map. A mapped delivered dose is computed for each region of interest using the dose delivery goals and the deformation map. The first treatment plan is merged with the segmented regions of the second image and the mapped delivered dose during optimization.

Abstract translation: 治疗计划系统和方法产生解释解剖变化的最佳治疗方案。 根据受试者的第一个图像，根据第一个自动计划的最佳治疗计划，将治疗传递给该受试者。 在一段时间后收到主题的第二张图像。 将第二图像与第一图像一起登记，以生成考虑生理变化的变形图。 使用变形图将第二图像分割成感兴趣区域。 使用剂量递送目标和变形图计算每个感兴趣区域的映射递送剂量。 在优化过程中，第一个处理计划与第二个图像的分割区域和映射的递送剂量合并。